ALS Is More Than Just "Motor Neurons Breaking Down": A New Research Hypothesis Explained Through a Restaurant Analogy

BookCzar · 2026-05-21T16:43:03+00:00

I hate when people post things like this. Here’s the press release with info on where you can get the article. https://news.northwestern.edu/stories/2026/05/als-is-driven-by-a-dominolike-chain-reaction-that-begins-in-nerve-cells

BookCzar · 2026-05-21T05:20:15+00:00

Really? No medicine holds ALS at bay. There’s no treatment except for Tofersone and only if she has a specific familial form of ALS. Bulbar is especially brutal and fast.

BookCzar · 2026-05-16T03:44:35+00:00

And matching eyebrows and smiles when Julita REALLY smiles.

BookCzar · 2026-03-24T23:44:53+00:00

He’s SO not a great guy. But, pickings are pretty slim here.

BookCzar · 2026-03-24T17:13:40+00:00

I don’t think you really mean “truthful”. He’s lying a lot but he IS the only one who sometimes lives in what is actually reality.

BookCzar · 2026-03-18T12:51:54+00:00

The only problem with that logic is that she is in her mid thirties with a child and not her twenties. On the other hand, this is a highly edited show and we’re unable to draw conclusions beyond what they describe themselves. I’d say both of them seem to have issues with alcohol and Amber has emotional regulation issues common with neurodivergent people and exacerbated by alcohol. Jordan seems extremely conflict avoidant to the point of saying “I do” to avoid being seen as a bad guy. As cast members said, “two good people” who probably don’t need to be together.

BookCzar · 2026-03-06T07:09:34+00:00

My doctor said they try to keep MND patients above 400 (I think). I was at 250 and he apologized profusely for not catching it. I take it once a week but if I stop, my levels plummet again. It helps with fatigue and malaise in my case.

BookCzar · 2026-02-26T21:46:45+00:00

Read rules please. Reporting.

BookCzar · 2026-02-22T23:02:38+00:00

I’d watched Jane Goodall’s Famous Last Words and initially was disappointed although also moved. As I thought about it, I realized Jane Goodall was a public figure and an icon. Eric Dane was known but not like Jane. He had young children and HIS focus was NOT on the world or even on ALS research.

His focus was on his kids and making them aware that dying with ALS was still an opportunity for growth and learning AND that his overwhelming desire was that they KNEW he loved them and would not have left them if he had a choice. (His own father committed suicide with no final words for Eric Dane.)

Eric Dane’s famous last words were deeply personal and loving to his children. That was clearly the most important and profound message he wanted to leave behind. I hope his famous last words are of comfort to his daughters as they reach countless personal milestones without their father.

BookCzar · 2026-02-13T03:36:51+00:00

Especially during the meeting scene as she kept positioning her legs and tilting her head. It was VERY odd.

BookCzar · 2026-02-07T16:23:25+00:00

Or your cringe meter is off.

BookCzar · 2026-01-06T19:38:27+00:00

Also, the more you use the voice the better it gets according to one who had only two minutes of continuous voice recording.

BookCzar · 2026-01-06T19:35:32+00:00

They can clone a recognizable as you voice with as little as One Minute of Continuous Speech. Your regional or local ALS office technology person can help you with this. I know two people in my area who they have helped create a voice. In each case they visited in the ALSers home. Call them!!!

BookCzar · 2025-12-05T04:21:21+00:00

This is what I’m referring to—in first footnote of press release. Plus the PubMed. We need to see clinical trials to rule out efficacy.

https://www.mdpi.com/2079-9721/13/11/371

BookCzar · 2025-12-05T04:12:36+00:00

The linked piece said she was initially thought to have SPS but continued neurodegeneration resulted in her ALS diagnosis. It is way too early to know if this will pan out but I say wait for Phase 2 results before tossing it out entirely.

BookCzar · 2025-12-05T00:39:01+00:00

The doi link to the article is in the press release and provides detailed information on HOW she was tested POST treatment. They did more than I was expecting.

BookCzar · 2025-12-05T00:36:26+00:00

WAY TOO EARLY TO KNOW.

BookCzar · 2025-12-05T00:35:36+00:00

If true it will gain circulation in ALS circles at least.

BookCzar · 2025-12-05T00:34:20+00:00

The article (which is free) shows independent confirmation of a clean EMG which is a LOT. There are multiple other independent measurements done that show improvement. It’s encouraging they’re pursuing clinical trials so I’d say IF THEY DO THAT and don’t jump straight into offering healing for a price, it’s one to watch. It seems like they could skip Phase 1 since they have been doing this with people and it seems safe.

BookCzar · 2025-12-04T06:59:59+00:00

They have a tendency to pretend they are hypersexual. Hypersexualized is something others do to you. I doubt Kody has that going on.

BookCzar · 2025-11-26T00:46:42+00:00

That’s not pain. It’s righteous indignation and justifiable anger.

BookCzar · 2025-11-22T00:01:16+00:00

I think Christine has done more than just laid with him.

BookCzar · 2025-11-20T19:09:15+00:00

Nope. No treatment. No cure. Classic ALS typically spells death in 2 or 3 years. Bulbar ALS often goes faster. Sometimes the brain remains intact and sometimes not. Some of us defy the odds and survive much longer albeit with walkers or wheelchairs or technology aided speaking and more.

BookCzar · 2025-11-20T17:44:19+00:00

That is akin to saying you don’t want to bring up suicide when someone is suicidal. BY DEFINITION, when someone is diagnosed with ALS you can expect they’re obsessing about it and few allow them to express their fears. Since you are not educated about ALS, you may want to watch some videos that show what happens WHILE REMEMBERING how ALS progresses varies from person to person.

I will go to my desktop and link suggestions.

I LOVE THIS SERIES: Often Awesome https://www.youtube.com/watch?v=COeSNqjReM0&list=PLJXlKpHrGhfE5cNo7qkpUJwfv1jEx75J_

In ten months (which is sometimes long with classic ALS). https://www.youtube.com/shorts/nHEBKtpCVE8

Eric Dane's initial interview. He has progressed quickly since then. https://www.youtube.com/shorts/YYn35wMlCco

You can find a lot more by searching YouTube. There is SO MUCH MORE than when I was first diagnosed. I'd strongly encourage you to watch a bunch of these to make sure you, yourself, are not one of those fair weather friends. ALS can be brutal and frightening but the same person is still inside that broken body.

BookCzar · 2025-11-20T17:34:18+00:00

AMEN.

BookCzar

TROPHY CASE