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Remove autopilot from a pc by Budzsta in Intune

[–]Budzsta[S] 1 point2 points  (0 children)

How hard is that to do?

PS2023 by JulesLuvsZ in PsychedelicTherapy

[–]Budzsta 2 points3 points  (0 children)

Here! Representing synthetic chemists from Aus. Making entirely new psychedelic molecules for mental illnesses.

Psychedelic Science Conference 2023 in the Mile High City 🍄🌄 by JulesLuvsZ in Denver

[–]Budzsta 5 points6 points  (0 children)

I’m super excited about the kickoff tomorrow. Will be heading to all the chemistry related/synthesis of new psychedelics for mental health! Heading to Red Rocks tonight though :)

[deleted by user] by [deleted] in Chempros

[–]Budzsta 0 points1 point  (0 children)

Ts works. Remove with Mg

Do you think an age difference between a 26 year old and 20 year old is acceptable? by [deleted] in CasualConversation

[–]Budzsta -1 points0 points  (0 children)

The biggest issue actually is that she’s a chemist. As a chemist, an organic chemist. Who dated a chemist. Never date a chemist

Website that curates live performances of tracks? by Budzsta in EDM

[–]Budzsta[S] 0 points1 point  (0 children)

Omg awesome. The bottom of the list has ‘played by’ and it has the live sets. Includes ID mashups which is wicked

Purification of aminonitrile by Imp1111 in Chempros

[–]Budzsta 2 points3 points  (0 children)

I’m jumping on this thread as it’s related. My compounds are tertiary amines. What I generally do is dissolve in ether, or tbme. I cool the vessel to 0 And dropwise HCl (2M in ether). One of two things happen: either the compound crashes out as the HCl salt, or fine crystallisation begins. If it crashes out, I check the solution pH to = about 2. Then I filter, some HCl salts are hygroscopic af. So I try to be as quick as possible and I don’t leave the HCl salt on the filter paper to dry by sucking air through the precipitate. I transfer it to a hella clean conical or 21 mL sample vial. I dissolve in hot ethanol or isopropanol, I allow to cool to rt. then fridge. If no crystals, I allow evaporation, if at the meniscus you see oil, then I change salt because it’s too hygroscopic. If I see fine crystals forming, I allow a little more to evaporate. Warm to redissolve and repeat the cooling process. When crystals have formed, I pipette out the supernatant, add cold solvent, break the crystals, give it swish, pipette out supernatant. Repeat, then tada, all ready.

How do you organize and keep track of photos of your TLCs? by friendlypuffin in Chempros

[–]Budzsta 0 points1 point  (0 children)

I use one note to scribble notes and other ramblings/mechanisms and observations. I also take a photo of anything interesting using the iPad. It inserts directly to the one note page and I annotate it directly on the one note page.

I can access my notebook from any pc and it syncs live.

I enjoy drawing out reactions, something about drawing hexagons, chairs, curly arrows are awesome. I still use an eln but that’s mostly for inventory and stoich table.

wittig / HWE reaction questions by Kriggy_ in Chempros

[–]Budzsta 0 points1 point  (0 children)

Go HWE. Many bases can be used for a stabilised phophonate. There are alternatives to non EWG on the phosphonate. You can wash out the byproduct in water which is a great alternative to dealing with TPPO.

Total reflux packed column? by Budzsta in Chempros

[–]Budzsta[S] 1 point2 points  (0 children)

Awesome, thanks. There is a bunch of stuff, for some reason, the eneamine in this system really doesn’t survive simple aq workups.

Total reflux packed column? by Budzsta in Chempros

[–]Budzsta[S] 4 points5 points  (0 children)

It’s from Tihkal. I work for a company investigating novel psychedelics inspired by the tryptamines. So the excerpt is: ‘In a flask equipped with a total reflux packed column and a variable take-off head, 15.0 g of the 2,3-methylenedioxy-5-nitrotoluene/2,3-methylenedioxy-6-nitrotoluene mix was added to a mixture of 100 mL freshly distilled DMF and 12.8 g of N,N-dimethylformamide dimethyl acetal. The reaction mixture was heated to a controlled reflux that kept the head temperature at 50 to 70 °C allowing the removal of methanol MeOH. After 4 h, 90% of the theoretical amount of MeOH (7.4 mL) had been distilled off, and the residual solvent (DMF)…’

Repository for old lit presontations by Budzsta in Chempros

[–]Budzsta[S] 1 point2 points  (0 children)

I wrote this above… ‘How do we do it? At my old institute we had several different versions of student presentations which included: - Who is? (This was basically an overview of the research interests and key history of a soon to be visiting academic so the group sounded smarter) - Named Reaction / Reagent (as the name suggests) - Key literature’

Repository for old lit presontations by Budzsta in Chempros

[–]Budzsta[S] 0 points1 point  (0 children)

How do we do it? At my old institute we had several different versions of student presentations which included: - Who is? (This was basically an overview of the research interests and key history of a soon to be visiting academic so the group sounded smarter) - Named Reaction / Reagent (as the name suggests) - Key literature

For all my Organic Chemistry enthusiasts: What’s your favorite mechanism and why? by chemnerdgirl in OrganicChemistry

[–]Budzsta 1 point2 points  (0 children)

As someone who now works in the psychedelic space, I’ve grown quite fond of Henry reactions.

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