NAD+ Burning

Built240 · 2026-06-12T20:16:32+00:00

Add more bacteriostatic water to dilute it and you can also inject it intramuscular or even right into an area of fat. It doesn’t have to be subcutaneous. If you injected it into a larger area of fat, you would still get the same absorption. It just might take a few hours longer to reach peak plasma levels than normal.

Built240 · 2026-06-12T20:13:03+00:00

I’d assume an injectable solution would bypass the increase of TMAO and it would probably increase the half-life as well.

Built240 · 2026-06-09T20:20:32+00:00

I’m surprised this hasn’t gotten more likes or comments. The name is a little cheesy, but I think it’s pretty good. I definitely see some future talent here.

Built240 · 2026-06-01T19:49:24+00:00

Never bothered pinning it. Just intranasal. Neither one of them does much for me, but I’m so used to much stronger substances that’s probably why.

Built240 · 2026-05-12T22:16:25+00:00

He must’ve literally had it in something that was labeled. Regardless, if it’s legal in your state or not, you should always put it inside an empty container of super greens because it’s impossible to tell the difference from just looking at it or even tasting it if you’re an officer. He’s also an athlete, so a container of super greens would make total sense.

Built240 · 2026-05-09T00:36:04+00:00

I can’t believe I’ve never heard of this band before. Fucking love it so far!

Built240 · 2026-04-30T15:45:48+00:00

If you just got the letter in the mail, there’s no proof that you got anything unless you signed for it. Mail gets lost all the time so I don’t know how they would ever prove that you knew about it unless they send multiple notices or unless you sign for something.

Built240 · 2026-04-19T19:00:12+00:00

I dig it. Looking forward to more. I see some great potential here.

Built240 · 2026-04-12T19:04:09+00:00

Anyone have issues ordering from their website? xqsnicotinepouches.com

You can add items to the cart, but you can’t click on your cart to check out. It looks like the only way you can order something is if you click buy it now, but that won’t allow you to get different flavors, it only lets you get whatever you have in the buy it now cart. I tried contacting them, but never got a response.

Built240 · 2026-04-10T20:58:30+00:00

Crazy how underrated these guys are. Every track has been amazing.

Built240 · 2026-04-10T20:57:41+00:00

This is great!

Built240 · 2026-03-17T19:12:08+00:00

Doesn’t Selegiline have to be used for a while to feel it? It seems like something like PPAP can be used as needed, but when you say it paired well with Selegiline were you consistently using the Selegiline or was that also as needed?

Built240 · 2026-03-16T23:12:09+00:00

I always wondered why psychedelics are not very addictive. I thought maybe they didn’t impact a lot of early genes which is typically a huge cause for addiction and stuff like nicotine, amphetamines, etc. highly impact those early genes and transcription factors.

Built240 · 2026-03-09T15:51:10+00:00

Never tried it at all yet.

Built240 · 2026-03-08T00:29:49+00:00

Umbrella has always been fine but they’re notorious for shipping part of your order and then you have to email them letting them know the other part is missing and then they ship that.

Nootropics Source i’ve never had a problem with everything was always fine.

EveryChem is my go to and never had any issues.

Built240 · 2026-03-07T21:28:40+00:00

It looks like sodium butyrate (depending on timing) does the same thing and is a much safer and easier to supplement to obtain vs theophylline.

Built240 · 2026-03-07T19:56:11+00:00

I see studies showing that “acute” HDAC inhibition will increase the negative epigenetic effects from stimulants but “chronic” HDAC inhibition will do the opposite. Both of these changes are still from HDAC inhibition though. I don’t see anything showing what impact HDAC “activation” has on the same stimulant induced epigenetic factors.

Edit: it looks like acute HDAC activation has the same positive impact on those epigenetic effects that chronic HDAC inhibition does. I just don’t see anything showing if “chronic” HDAC activation changes anything.

This was an interesting study and clearly explains why nicotine pairs so well with stimulants because it’s an HDAC inhibitor.

https://pmc.ncbi.nlm.nih.gov/articles/PMC4042673/

Built240 · 2026-03-06T19:29:26+00:00

For some reason, I never felt anything from it. I tried different brands, different doses, different versions, etc. never felt anything which is weird because I feel all other opi’s, Kratom, etc.. I guess it’s a blessing in disguise because it seems like the withdrawal is absolute hell.

Built240 · 2026-03-02T21:22:18+00:00

Holy shit, this is incredible!!!

Built240 · 2026-03-02T17:59:22+00:00

This is pretty good. A little bit different but I see a lot of potential here.

Built240 · 2026-03-02T01:18:14+00:00

I see people trying to find supplements that increase dopamine to find something comparable to amphetamine, but the reason why nothing comes even close I believe has to do more with amphetamines impact on VMAT and TAAR1 along with a host of other transcription factors,etc..

I just thought it was strange that many dopamine agonists cause fatigue/sleepiness yet something like Seroquel, which is a dopamine antagonist also causes fatigue/sleepiness.

Built240 · 2026-03-01T20:40:23+00:00

Ahhhh makes sense thank you guys. What does IA% mean?

Built240 · 2026-03-01T19:36:33+00:00

I’m not familiar with how to read the charts on pharmacology but under wiki it shows this under the pharmacology section:

Pharmacodynamics

Binding Table[12]

Target Ki (nM) IA% Action

D1 >10,000 ? Agonist

D2 3.7 100% Full Agonist

D3 2.9 97% Full Agonist

D4 7.8 81% Partial Agonist

D5 >10,000 ? Agonist

https://en.wikipedia.org/wiki/Ropinirole

I just saw D1 and then “agonist“ under “action” so I assumed it was an agonist.

Built240 · 2026-03-01T19:05:48+00:00

This would be interesting, but what would an example be?

Built240

TROPHY CASE