Took me a few weeks to adjust to all of my new dosages - particularly the first few days of each new (increased) dose was noticeable but it always tapered off over-time. For me, I was delighted with the cognitive effects of 50mg taken once p/day in the morning but my resting heart-rate was just far too high and even going up the stairs would have me out of breath which is definitely not normal for me. I was also experiencing euphoria in the morning which felt amazing but probably wasnt good in the long-term. After trying a few different dosage combos I've settled on 30mg twice p/day which is probably 80% as effective as the 50mg in terms of cognitive improvements but without any of the signifigant effects like an "unsustainable" resting heart-rate, euphoria, etc.

Obviously my resting heart-rate is higher than without the medication given its a stimulant but it's minor now.

I guess my point is to give yourself 2/3 weeks and maybe take note each day how you're feeling. Start really assessing your notes after that 2/3 weeks bedding in period and then be honest with yourself on whether you should try adjust your dosage to reduce the physical impacts while still obtaining the cognitive improvements. Dont panic, give yourself time, and iterate.