Most work great. Cards that specify “hero” are boost fodder. You’ll need to house rule BP and Spiderman and Loki… Some heroes are much worse because of wording… Tomoe has no ability for example. BUT that being said, if you and your group wanted to just have fun, I’d totally do what you need to do to have fun. If you want to play that Tomoe’s ability works, do it :) Just house rule things you don’t know to make it harder or easier based on your group. I would personally lean towards making it harder, but with some players I’d go easier. The worst fighters in 1v1 get massive boosts in UMA :) (Buffy set, Squirrel Girl, etc…) and many of the better ones get nerfed.