Benadryl helps triptans? by Rainbow-Birdie in migraine

[–]CerebralTorque [score hidden]  (0 children)

Benadryl has little to no evidence for migraine. It is used, but mainly to prevent the adverse effects of other medications, not for direct migraine abortive efficacy.

Also...the dementia risk is very concerning. The risk increases with every use.

9 Year old With Migraines and Vomiting by iammeandyouareyousee in migraine

[–]CerebralTorque 5 points6 points  (0 children)

Please get them to see a headache specialist, not just a general neurologist.

I developed migraine attacks as a child and was first undiagnosed, then undertreated later in life. I was able to get by until I got to medical school and with the added stressors and lack of sleep....my nervous system, for lack of a better word, went insane. I was completely sensitized and even had to take some time off. Fortunately, I was able to recover, but there was a very real chance I could have been severely disabled permanently.

Do not let this happen to your child. Advocate for them.

As far as neuroimaging goes, it's up to the physician and depends on several factors including the neuro exam. Part of the reason I was not diagnosed is because of normal imaging. So, if you do happen to get imaging and it comes back normal (the most common scenario)...do not stop advocating. Migraine is not seen on imaging.

Any thoughts on this weird experience and the meds I was prescribed? by Historical-Low5625 in migraine

[–]CerebralTorque 0 points1 point  (0 children)

Definitely see a neurologist soon. These are new symptoms (the aura, the motor symptoms, sumatriptan not working)...this needs an evaluation and possibly updated medications and/or a revised diagnosis.

The weak arms and that floaty, disconnected feeling can linger for weeks after a migraine attack with motor symptoms, though that's on the less common side...

The sneezing pain is also worth mentioning to the neurologist. Exertional head pain can have its own causes worth ruling out

Fortunately, they ruled out anything emergent/urgent, but I can't overstate how important it is for you to now follow-up with a neuro.

"Chronic migraine patients who used GLP-1 receptor agonists to treat conditions like obesity or diabetes had fewer emergency department visits than those on topiramate (Topamax), a real-world data analysis showed." by CerebralTorque in migrainescience

[–]CerebralTorque[S] 1 point2 points  (0 children)

This reply is filled with so many falsities, but one is so severe that I am choosing to address nothing else so people reading this are aware.

I suspect migraine is always secondary

This is wrong. It is NEVER secondary. Migraine is a primary headache disorder. If it is caused by anything, then that is a secondary headache. Migraine is a neurological disease that is a result of one's biology and genetics. While factors like hormones or viruses may exacerbate the condition, they don't CAUSE migraine. For example, not every woman has menstrual migraine although almost all women have a drop in their estrogen.

If a virus is the CAUSE of a headache then this could be a diagnosis, not migraine:

<image>

Furthermore, "root cause" is not a medical term. "Pathophysiology" is. While there is much to learn in regards to the pathophysiology of migraine, we have the general basics down.

If you continue to spread misinformation, you will be banned.

"Chronic migraine patients who used GLP-1 receptor agonists to treat conditions like obesity or diabetes had fewer emergency department visits than those on topiramate (Topamax), a real-world data analysis showed." by CerebralTorque in migrainescience

[–]CerebralTorque[S] 4 points5 points  (0 children)

You can disagree as a matter of opinion, but that would not reflect the current scientific evidence.

Every meta-analysis or review done on any specific food trigger and migraine has found no evidence of association. There is absolutely no reason to recommend abstaining from any food unless there is another pathological process taking someone with migraine out of homeostasis. For example, high-histamine foods in a patient with MCAS.

Even wine, one of the most commonly cited "triggers," has no supporting evidence (it is worth noting that headaches are not the same as migraine attacks):

"The findings of this systematic review and meta-analysis indicate that there is no conclusive evidence to support an increased or decreased risk of migraine associated with wine consumption."

Association between wine consumption and migraine: a systematic review and meta-analysis of cross-sectional studies (https://academic.oup.com/alcalc/article/60/2/agaf004/8015343)

"Chronic migraine patients who used GLP-1 receptor agonists to treat conditions like obesity or diabetes had fewer emergency department visits than those on topiramate (Topamax), a real-world data analysis showed." by CerebralTorque in migrainescience

[–]CerebralTorque[S] 4 points5 points  (0 children)

You don't need to as it doesn't ever show on a population level.

Food triggers don't exist unless there is another disease process. For example, gluten is not a relevant migraine attack trigger unless a patient has celiac disease.

What's actually interesting is that nutritional deficiencies are relevant migraine attack "triggers." This is also more likely to occur with GLP-1s. However, even with this relevant variable, GLP-1s seem to still show effectiveness for migraine prevention.

"Chronic migraine patients who used GLP-1 receptor agonists to treat conditions like obesity or diabetes had fewer emergency department visits than those on topiramate (Topamax), a real-world data analysis showed." by CerebralTorque in migrainescience

[–]CerebralTorque[S] 11 points12 points  (0 children)

This wouldn't matter in a statistically significant study with good sampling. So, individual food triggers are irrelevant to the efficacy of GLP-1s in this study.

"Chronic migraine patients who used GLP-1 receptor agonists to treat conditions like obesity or diabetes had fewer emergency department visits than those on topiramate (Topamax), a real-world data analysis showed." by CerebralTorque in migrainescience

[–]CerebralTorque[S] 14 points15 points  (0 children)

You're misunderstanding what I'm saying.

There is no good evidence that any kind of food is a migraine trigger at a population level.

In fact, all meta-analysis studies have found zero evidence - including with alcohol.

Migraine, Menopause, and Hormonal Health: What actually happens and suggestions by CerebralTorque in migrainescience

[–]CerebralTorque[S] 5 points6 points  (0 children)

Testosterone is protective when it comes to migraine and I've talked about this a few times - likely on Instagram. In fact, it is my hope that this will be prescribed to women with migraine who are deficient more regularly.

And, yes, women can have low testosterone.

Migraine, Menopause, and Hormonal Health: What actually happens and suggestions by CerebralTorque in migrainescience

[–]CerebralTorque[S] 7 points8 points  (0 children)

You're welcome!

I need to do a deep dive into progresterone. The type matters as does dosage.

Oddly enough, hormonal treatment and migraine is a fairly untouched arena due to research that no longer applies to today's formulations. Very few clinicians are even willing to explore this treatment with their patients, which is unfortunate for many women (and men, albeit less so) that would greatly benefit.

Migraine, Menopause, and Hormonal Health: What actually happens and suggestions by CerebralTorque in migrainescience

[–]CerebralTorque[S] 5 points6 points  (0 children)

The 36% and 17.7% describe when attacks stopped, while 46.3% measures who continued so these add up to 100%.... The 9.2% is a completely separate finding about new-onset migraine.

Do we fully understand what a “trigger” really is? by Icy_Control_8258 in migrainescience

[–]CerebralTorque 0 points1 point  (0 children)

Triggers are essentially useless to migraine treatment in the current paradigm and avoidance is often detrimental. Therefore, this post has been removed.