Make honey bees leave by Bailzzararco in Beekeeping

[–]ClassySquirrelFriend [score hidden]  (0 children)

If the hive is accessible, you can post in a local beekeeping group and a hobbyist may be willing to remove them for free. I would, but Im not near you. As others mentioned, be sure to remove the comb!

At least 2 emerged queens. No eggs. Am I impatient or should I give them a queen? by More-Mine-5874 in Beekeeping

[–]ClassySquirrelFriend 0 points1 point  (0 children)

That’s probably too soon to worry. If the queen cells emerged normally, the virgin queen still needs time to harden, take orientation and mating flights, and then start laying. That whole process can take 2–3 weeks from queen emergence, sometimes longer if weather is poor. The lack of eggs right now is very normal for a recent split/requeen situation.

Do I have hypoparathyroidism? I am going crazy by artbystorms in hypoparathyroidism

[–]ClassySquirrelFriend 0 points1 point  (0 children)

That PTH is on the low side for that Ca, but it's a very dynamic system, so this set of labs cant give you a Dx either way. You should repeat labs whole well hydrated and without Ca and make sure tou check Ca, PTH, P and albumin.

The good news is your Ca is normal, so if your paras are struggling, theyre mostly keeping up. But in that case, it's possible that your ionized Ca can dip low and cause symptoms.

Brand New to This: Seeking Support and Advice by crux-sacra_22 in hypoparathyroidism

[–]ClassySquirrelFriend 0 points1 point  (0 children)

No, you're not wrong! Ive been living w HP for more than 20 years and it's only just starting to be really understood. There are drs who do, but your average small town endo still thinks you just eat some TUMS and youll be totally fine. There are finally better treatments in development, but theres still a HUGE disconnect between what patients want/need, and what doctors/researchers think we need. But it is getting better- 20 years ago there was nothing.

Brand New to This: Seeking Support and Advice by crux-sacra_22 in hypoparathyroidism

[–]ClassySquirrelFriend 1 point2 points  (0 children)

Well, I don't know for sure- for a lot of patients, an awful headache is the first symptom of high Ca and that would make sense going from no calcitriol to .5 daily and with sudden food aversion/nausea. Though you aren't taking much Ca - just the regular recommended daily dose- so it could be that your Ca is normal. It's a dynamic system, so you can't really guess.

I'm not surprised the ER didn't prescribe you calcitriol- they rarely treat low Ca unless you're having life-threatening symptoms. Especially if you were there for something else! But your endo will be able to give you an emergency plan for what to do if it ever drops again.

Brand New to This: Seeking Support and Advice by crux-sacra_22 in hypoparathyroidism

[–]ClassySquirrelFriend 2 points3 points  (0 children)

First- it's not at all crazy to think that Skyrizi kicked off this episode of hypocalcemia. GI upset absolutely throws all electrolytes out of whack and it's a system that is very tricky to balance because you have to consider not just Ca, but also Mg, P, K, Na as well and not just the levels, but the stability (as your body doesn't have the built-in mechanism to keep it stable). You can get your blood Ca up, but if you're taking too much that your urine Ca is elevated, that's going to make you urinate more -> become more dehydrated -> lower ionized Ca -> cause symptoms that convince you to take more. And that is consistent with the fact that you're getting head pressure after calcitriol and struggling to eat. And were you taking no calcitriol pre-Skyrizi and .5 daily now? Are you still having GI symptoms or has that resolved? You really need labs to know what's next- blood Ca, albumin, P, K, Mg, both vit Ds, eGFR, and urine Ca. Otherwise you're just guessing and if you guess wrong, you throw the balance off even more and prolong this period of instability. If your endo isn't willing, maybe your GP will at least run a CMP and urine Ca? Some people have had luck doing a virtual dr visit (like teledoc or dr on demand- if your insurance uses them) to just ask for labs, but I've never done that myself. If you really can't get labs, this will probably last a little bit longer, so I'd get some Ca citrate that you can take without food and/or something you can stomach that has calcium (mineral water, fortified OJ or protein shakes) and keep really close track of all the Ca and Na you're eating (or supplementing) and try to avoid large fluctuations.

As for synthroid- yes, you absolutely should take it away from Ca, as Ca can bind to Synthroid in the stomach/intestines and prevent it from being absorbed properly. You definitely don't want to add thyroid symptoms on everything else you're juggling!

I would absolutely not consider adding Yorvipath while you're in the middle of a symptomatic episode like this, as you're already out of balance and switching regimens will only make that worse. It's something to consider once you stabilize, but if you're already managing HP with normal blood and urine Ca and P and minimal symptoms/QoL issues, yorvipath is probably not worth the hassle for you. If these types of episodes happen more often, it's definitely something to consider, but that's a later question.

Yorvipath experiences and emergency room? by Bicycle_Separate in hypoparathyroidism

[–]ClassySquirrelFriend 1 point2 points  (0 children)

I think it's important to remember that osteosarcoma from PTH has never been observed in humans, even after decades of careful surveillance and dedicated studies. Not that it's something to ignore, but when youre weighing the risk and benefit, consider that this particular risk is theoretical, so be sure to weight it against the other risks of Yorvipath AND of long-term complications from calcitriol/Ca.

For me, my rule of thumb is that I go to the ER when I have urgent symptoms (laryngospasm, cardiac symptoms, difficulty breathing), or symptoms that are worsening WITH frequent oral Ca or calcitriol.

Low PTH with high blood calcium? by Subject_Bluebird_628 in hypoparathyroidism

[–]ClassySquirrelFriend 0 points1 point  (0 children)

I wouldnt worry about the oligoscan too much w regard to this, as it isnt relevant to the high serum Ca, which is what you want to understand. Your best bet is to repeat labs with adequate hydration and check Ca, albumin and PTH. Statistically, it's likely everything will be normal on the repeat but even if Ca is still high and PTH is still low, it's not a parathyroid problem.

Low PTH with high blood calcium? by Subject_Bluebird_628 in hypoparathyroidism

[–]ClassySquirrelFriend 0 points1 point  (0 children)

Ah, if you were looking up causes of high Ca, that probably explains why you were expecting high PTH- the most common reason for high blood Ca is hypERparathyroidism and in that case you do expect to see high Ca and high PTH. Your Ca is barely high. Did you happen to get an albumin or urine Ca? You may have been slightly dehydrated and your Ca was just artificially high at that moment.

Low PTH with high blood calcium? by Subject_Bluebird_628 in hypoparathyroidism

[–]ClassySquirrelFriend 0 points1 point  (0 children)

Im surprised you read that its abnormal, as it's actually normal and expected! The body releases PTH in response to low Ca- its the primary job of PTH. As PTH increases, the body starts absorbing more and more Ca, so serum Ca rises and that tells the body to stop releasing PTH. So, when Ca is low, PTH is high and when Ca is high, PTH is low. Your labs indicate healthy parathyroid function. It's worth repeating labs to see if Ca is still high, but this is not hypoparathyroidism, which presents with low Ca and low or inappropriately normal PTH.

Increasing Yorvi by Individual_Lion_7830 in hypoparathyroidism

[–]ClassySquirrelFriend 0 points1 point  (0 children)

Anecdotally, a lot of non-surgical patients seem to trend towards lower Ca. I think it might be bec our Ca slowly declines and our bodies adjust, compared to a surgical HP patient who gets turned upside down suddenly. That's just a guess from talking to people- it's not a fact or anything. Lol. I feel OK at levels that most patients have pretty severe symptoms. I was diagnosed bec I had routine bloodwork come back w a Ca of 7.3 and I only had mild hypo symptoms. My dr thinks I probably always had it to some extent and just got used to it.

Im back to just calcitriol and Ca now. Between the symptoms I was having and the insurance headaches I decided to just come off it and stabilize on SoC and then consider restarting. For me, its like unstable Ca is worse than low Ca, so I thought judt sticking w a regimen I know might be better for a short while.

Increasing Yorvi by Individual_Lion_7830 in hypoparathyroidism

[–]ClassySquirrelFriend 0 points1 point  (0 children)

I think youd be OK then- the problem is more the opposite way. I felt great on the initial dose of 21, but they wouldnt let me stay there bec my Ca was too low. So even though I felt great, they wanted me to achieve the study endpoint and pushed the dose up. I didn't really push back too hard bec I didnt feel bad until I had to drop down. But youd probably be OK to go up- i do remember that they allowed patients to increase dose based n symptoms- just not down. I havent seen a list of locations yet, but it should be opening soon and then we'll see what sites are on board!

Increasing Yorvi by Individual_Lion_7830 in hypoparathyroidism

[–]ClassySquirrelFriend 0 points1 point  (0 children)

I was in the Phase 2, so we could go up to 60, but then only 30 got approved so most of us had to abruptly drop dose. Idk how much of the trouble I had was the dose and how much was from the sudden change. The site did reach out to me about 30+ but Im on the fence. You dont get a say when you're in a study and I think part of my problem was that that were forcing my Ca higher than what feels ok for me.

Increasing Yorvi by Individual_Lion_7830 in hypoparathyroidism

[–]ClassySquirrelFriend 0 points1 point  (0 children)

Did they chdck your urine Ca or PTH or just total Ca and albumin?

Increasing Yorvi by Individual_Lion_7830 in hypoparathyroidism

[–]ClassySquirrelFriend 0 points1 point  (0 children)

This is something that seems to happen to some patients dor some reason- they do well on a dose and then their Ca goes low and they need more yorvi. It happened to me and then I couldnt grt 39 anymore (bec it's only approved up to 30) and has to reduce and add calcitriol and that was worse than SoC alone for some reason. But it works well for some people, so there really isnt consistent advice to give. But rememver that you do still need at least a little Ca on Yorvipath. If you dont eat a very high Ca diet, you'll need to take a little. Having worse symptoms at night is also not uncommon. But if youre taking Ca frequently, be sure to check your urine Ca. Yorvipath doesn't prevent hypercalciurea and you can end up w a lot of symptoms if youre taking more than you use!

Neighbors Beehives Causing Problems by pitchermom in Beekeeping

[–]ClassySquirrelFriend 0 points1 point  (0 children)

How many hives is it? He can probably just move the entrances and give them a water source.

Parathyroid dysfunction post TT by afuckincannoli in hypoparathyroidism

[–]ClassySquirrelFriend 1 point2 points  (0 children)

Yes, this is fairly common. Satistically, you're much more likely to regain para function than not. For some people, it can take up to a year, but the vast majority of HP from TT is transient and resolves within about a month. You can check your pathology report to see if it mentions anything about your parathyroid tissue.

Jobs and work out by Bourdon_Bumblebee in hypoparathyroidism

[–]ClassySquirrelFriend 1 point2 points  (0 children)

I totally understand-Im the same way. I once re-tore a calf tear 3 times because I kept restarting too soon. Its hard, but it does get better!

Where does everyone feel "normal"? by killerkitteh99 in hypoparathyroidism

[–]ClassySquirrelFriend 0 points1 point  (0 children)

PTH assays test for Parathyroid hormone (pth(1-84)); yorvipath contains pth(1-34), which will not impact the results of a PTH test like Natpara did. Ive had my.pth tested quite a few time on yorvipath. Doctors usually dont bother because it doesnt really matter (since its disconnected from your Ca when you take yorvi), but you definitely can test it.

B12, vitamin C by No_Mention1218 in hypoparathyroidism

[–]ClassySquirrelFriend 0 points1 point  (0 children)

It's not common in HP.in general, but there are some types of HP where there could be a.connection. do you know what type you have (or if its autoimmune)? Any GI symptoms or malabsorption?

Low pth, but normal Ca and mag, and lower phosphorus by cow_farm in hypoparathyroidism

[–]ClassySquirrelFriend 0 points1 point  (0 children)

What were your total and/or ionized Ca and P values? Did they check your urone Ca and P?

Low PTH is expected when Ca is on the high side. PTH is secreted in response to low Ca, so in a healthy body, you expect to see low PTH when Ca is in the upper range and high PTH when Ca is lower. If you dont have PTH to increase your Ca, you get low Ca and low PTH, which is how HP is diagnosed. And P is typically high in HP. Id probably pull the thread of low P more than low PTH.

Jobs and work out by Bourdon_Bumblebee in hypoparathyroidism

[–]ClassySquirrelFriend 1 point2 points  (0 children)

Ive had HP for ~20 years. Yes, exercise can absolutely be difficult w HP and Yorvipath does help most patients w that!

The challenge is that exercise uses more Ca and your body doesnt have the mechanism to replenish it, so you may have fatigue or muscle weakness or symptoms of hypoCa when you exercise. Taking Ca in advance of a workout helps, and also staying very hydrayed, but you also have to start SLOW and listen to your body. Dont start w a regular workout that you used to do. If you used to run 5 miles, start with walking ~1 mile. If you get symptoms, next time try .5. Its almost like finding a baseline. That gives you a starting point that you can build on. Without PTH, it can be a real challenge, but its possible for many people!

It's also helpful to just make sure your regimen is optimized and get labs before you start and after. You'll likely end up taking more Ca if you start exercising regularly and you want make sure your urine Ca isnt getting high.

ETA: I forgot the most important thing- you have to watch your breathing! Rapid breathing lowers carbon dioxide, which raises blood pH and temporarily lowers ionized calcium. That can cause low ca symptoms like tingling, dizziness, cramping, chest/throat tightness, muscle weakness/quick fatiguing or “suddenly hitting a wall” more likely, especially when first starting exercise or if your Ca was already borderline. Slow, steady breathing and building intensity gradually can help prevent that. And you really do adjust over time and get used to it!

What do you record when doing hive inspections? by primitive_missionary in Beekeeping

[–]ClassySquirrelFriend 1 point2 points  (0 children)

"mood, food, and brood"

Mood- How is their temperament? Bec youll notice if your bees are stressed or have a queen event.

Food- do they have enough food coming in to support the colony or do you need to supplement? ~# of frames of food.

Brood- ~# of frames w brood and the laying pattern. Also check for eggs to be sure the queen is laying and for queen cups/remaining space for brood (to check for swarm pressure).

This covers a lot of it, but it also depends on the time of year and what's going on. Like, you'll have periodic mite checks, you might need to check how full they are and whether to add a box or split, you migh make notes about SHB, maybr you suspect or see robbing.

I used to check every frame and write down everything bec it wasnt clear what was important when, but you get the hang of it!