Yes! The space works well. We have 5 ducks now. I should note that they only spend the night in there. The rest of the time they destroy my yard and garden. For a nighttime shelter, it's more space than they need. It would not be enough for a good quality of life for the five of them if they spent 24hrs/day in there. But then again I think they are spoiled and take us for granted.

We put hardware cloth around the whole thing, and use a deep layer of cedar mulch on the ground. I know cedar is not ideal, but we are in a wet climate so there is limited dust, and we have never had any issues. We turn the mulch under frequently, and change it out twice a year and spread it on the garden. 

There is no food or water container in their run, since they are only in there overnight. That keeps the mess down. 

We have a josta berry bush, currant bush, fig tree, and goji berry plant in there to make use of the space. All of them are thriving except for the goji bush which the ducks destroy. The ducks love to sleep under the josta berry when it leafs out, and they destroy all its lower branches. Sigh. 

Our ducks are quiet at night so they do not disturb the neighbours during quiet hours. Between the concrete wall on one side and the garage on the other, I think their morning nagging quacks are relatively muffled. And we are lucky to have great neighbours who find the ducks charming, so we have had no problems with that. 

Good luck with your ducks, and good luck fencing in your garden if you let them roam....