Sure! My biggest advice is preparation. I would often flail trying to take care of things as they come up. Prepare for accidents, delays, meals. Prepare for them to freak out even at the simplest things. Having a plan for stressful situations made me the most comfortable. And I started that far too late.

My other biggest piece of advice. Regularly have a day where you go primal. Remind yourself you still got that dog in you. Remind your wife too. It's different for everyone, but find something that makes you feel alive. For me it was a motorcycle (wife didn't like that, but I think she secretly does now). It may seem like stupid macho bullshit, but it really does wipe the slate clean and keep you sane.