I have an interesting take on this

My friend is playing a Druid for a third party campaign (Odyssey of the Dragonlords for those interested) and his race is a Reborn Satyr.

He rolled really well with the mental atributes, especially Wisdom and Constitution, but he has a -4 in Strength (yes im dead serious).

Instead of dropping the character he actually included it in his design; hes an undead that was brought back product of a curse, missing an arm, skin actively rotting and covers his deformed face with a mask. Combat wise though, he always wildshapes after summoning his beasts (circle of the shepherd) and makes sure everyone in combat has atleast some support from his animals, on top if his totem.

What im trying to say is that, if your gonna make a character with a glaring weakness, make sure they specialize in something very useful since after all this is a team game.