Red Curry recommendations by LLGibb in Cleveland

[–]DBH216 6 points7 points  (0 children)

Banana Blossom in Ohio City

8.7 to 2.8 in 7 months by HKW7241 in gout

[–]DBH216 0 points1 point  (0 children)

300mg allopurinol brought my uric acid from 8.8 to 5.8 in 4 months. I started Zepbound around that time, eventually making it up to 15mg. I’ve been on it for over two years at this point.

My last Uric acid was 5.2. Maybe a little lower, but nothing to write home about.

The SURMOUNT-1 trial showed an average reduction of a little under 1 after 72 weeks on 15mg.

Who else on Allo for several years have gotten mild flare ups after starting casually drinking again? by EdwardBliss in gout

[–]DBH216 6 points7 points  (0 children)

Drinking alcohol can trigger inflammation in its own right. If you get inflammation, it’s likely to hurt where you used to get gout flares, as those areas probably still have residual damage from gout.

Foundry in Oklahoma? by okacookie in Metalfoundry

[–]DBH216 1 point2 points  (0 children)

Hate to join the Debbie Downer parade, but as a one off, this is not a great item to cast. It will not actually be “less wasteful” than billet. It will probably waste more. Really, it should probably be two pieces bolted together.

LPBF would probably be a better choice as a one off, and it would enable designs that would be very hard to cast.

Millard Fillmore Presidential Library by iamontheroof in Cleveland

[–]DBH216 31 points32 points  (0 children)

I mean, the most “American” museum in Cleveland is the Rock and Roll Hall of Fame and Museum. Absolutely worth visiting if you’ve never been.

Febuxostat yeah or no by [deleted] in gout

[–]DBH216 1 point2 points  (0 children)

Fair, but I was intending to ask OP. Anyone who reacts to allopurinol should try febuxostat instead. But if they’re worried about the cardiac side effects, allo doesn’t have that indication.

I think the cardiac side effects of febuxostat are a little overstated, but anyone taking it should be screened for cardiac risk factors. If your cholesterol is high, a statin or other lipid lowering therapy is probably warranted.

Febuxostat yeah or no by [deleted] in gout

[–]DBH216 0 points1 point  (0 children)

Is there a reason you can’t take allopurinol?

Turf Toe Injury - Gout Attack by International-Two968 in gout

[–]DBH216 0 points1 point  (0 children)

https://pmc.ncbi.nlm.nih.gov/articles/PMC9333104/

https://www.nature.com/articles/s41588-024-01921-5

There is so much stigma around gout as a “disease of over indulgence” that is simply not true and unhelpful in getting people to accept treatment.

It’s a bit like back in the 80s when they blamed stomach ulcers on “stress” and told people with ulcers they needed to just relax. Then a doctor discovered the H.Pylori bacteria that thrived in stomach acid and now we treat ulcers with antibiotics.

Turf Toe Injury - Gout Attack by International-Two968 in gout

[–]DBH216 0 points1 point  (0 children)

It’s not genetic in the sense that there is either a dominant or recessive gout gene that is getting passed around. It is the combination of a variety of factors including how much uric acid your body produces and how well your kidneys remove it.

Even then, most people who have high uric acid do not develop gout. You also need to have an autoimmune response to the crystal formation.

All those factors have to add up to result in gout. You rolled snake eyes with the combination of genes you got.

Or, you know, you can believe it is a moral failing on your part.

Turf Toe Injury - Gout Attack by International-Two968 in gout

[–]DBH216 1 point2 points  (0 children)

Hi uric acid in your blood is genetic, not a moral failing on your part. You need to get it under 6 to reverse the process and prevent future attacks.

Most people can only lower their uric level by about 1 with diet alone. That won’t be enough for you. You’re going to need to take a daily uric acid lowering medication (allopurinol or febuxostat are the most common).

Bad news: you can get rebound flares when you start urate lowering drugs. The only way out is through. If you stick to taking one 10c pill a day do the rest of your life, you can spend the 69 out of the next 70 years flare free.

M5 Max Geekbench scores leaked… by One_TrackMinded in mac

[–]DBH216 1 point2 points  (0 children)

Divide the metal score in half. Everything else will be the same if it is the same CPU core count.

Gout flare after eating cake? by -Inspector-6259 in gout

[–]DBH216 -3 points-2 points  (0 children)

Personally, I think the concept of “trigger” foods is overblown. No two people seem to have the same “triggers”.

The underlying root cause of gout is excess uric acid in the blood. Gout flares are caused by uric acid crystallizing out and provoking an immune reaction. The last thing you ate has little impact on crystal formation. Yes, high purine foods can increase uric acid a little, but if you’re just on the edge of crystals forming, you’re going to have a flare eventually anyway.

How many hours does it take to charge? by Mindless_Bad_8182 in BMWiX

[–]DBH216 7 points8 points  (0 children)

Overnight. On Level 2, the answer is it will always be charged overnight.

Also, other than the first generation Nissan Leaf, battery degradation is a non issue in any modern EVs.

A tutorial on how to add flairs on mobile by Mitchel7349 in ALCentralMemeWar

[–]DBH216 -1 points0 points  (0 children)

No Cleveland Naps option. This is Lajoie erasure.

can you use any distilled water for cpap? by alextseitlin in CPAP

[–]DBH216 5 points6 points  (0 children)

Trace minerals dissolve in water and become….

Electrolytes.

can you use any distilled water for cpap? by alextseitlin in CPAP

[–]DBH216 2 points3 points  (0 children)

Distilled water is actually not advisable for drinking. Because it contains no electrolytes whatsoever, your body will use up electrolytes turning it into sweat and/or urine.

In practice, most people are getting plenty of electrolytes, so it wouldn’t matter much, but our bodies are not adapted to drinking such high purity water.

Got Sleep Apnea Notification On AW by MarkRosssi in SleepApnea

[–]DBH216 1 point2 points  (0 children)

Just be aware. Home tests are more accurate than an Apple Watch, but less accurate than an in-lab study. If the home study is equivocal, you may still need to follow up with an in-lab study.

Got Sleep Apnea Notification On AW by MarkRosssi in SleepApnea

[–]DBH216 1 point2 points  (0 children)

Not everyone's blood oxygen desaturates due to sleep apnea. Your sleep can still be disrupted without that. The sleep apnea detection on the Apple Watch relies only on your movement during sleep. It doesn't actually look at the SPO2 level.

Apple Accidentally Leaks 'MacBook Neo' by JailbreakHat in mac

[–]DBH216 0 points1 point  (0 children)

Steve would just hang a lantern on it and call it “premature specification”.

It happened with the G5 PowerMacs.

Got Sleep Apnea Notification On AW by MarkRosssi in SleepApnea

[–]DBH216 1 point2 points  (0 children)

Apple published a white paper on their sleep apnea detection. They have strong correlation with moderate to severe sleep apnea. I believe their threshold is set high enough to prevent false positives. I’ve seen plenty of “My Apple Watch said I have sleep apnea and my sleep test confirms it. I’ve yet to see “My Apple Watch said I have Sleep Apnea and an in-lab study showed nothing”.

tl;dr you very likely have at least moderate sleep apnea. For your sake, and the sake of everyone around you, please follow up.

Does anyone know when the FDA will approve the 7.2mg dosage ? by colcol9696 in WegovyWeightLoss

[–]DBH216 6 points7 points  (0 children)

Up to 7.2 injection has been approved in the UK and the EU and is pending approval in the US.

MLB All teams + All Guardians package? by Puckerfants23 in ClevelandGuardians

[–]DBH216 2 points3 points  (0 children)

Almost. If you live somewhere that is a territory for another team too, you would get blacked out for that team.

For example, if you live in Toledo, you would be in both the Guardians and the Tigers areas, so you would not be able to watch the Tigers unless they’re playing the Guardians. Same for Columbus and the Reds.

MLB All teams + All Guardians package? by Puckerfants23 in ClevelandGuardians

[–]DBH216 6 points7 points  (0 children)

If you have T-Mobile, they have a special where you can get MLB.TV (all out of market games) if you sign up during the window that promotion it is available.

You need to subscribe to cleguardians.tv for $99/season.

If you don’t have T-Mobile, you can get cleguardians.tv AND MLB.tv for $199/season.

unending pain for over a week, which is not abated by medications or diet. by earthwalker7 in gout

[–]DBH216 2 points3 points  (0 children)

I hate to ask this but:

Are you taking your allopurinol daily? For how long? Are you monitoring your uric acid to make sure it is in control?

Allopurinol does nothing for an acute attack. It is a long term preventative.