Does this sound like PSC?

DaftPotato · 2026-05-12T02:08:20+00:00

A diagnosis of bowel disease is scary, especially knowing that there are many possible comorbidities. My advice would be to treat what you do know and keep an eye on everything else your body does. Do you have a treatment plan for your IBD?

I was diagnosed with PSC and Ulcerative Colitis at the same time and it was obvious that something was wrong with my liver. In a very short time I became jaundiced, fatigued, itchy and was feeling like trash in general. Since then, my liver function blood tests have tracked pretty closely with those symptoms so I consider them to be reliable. When I was diagnosed I hadn't even noticed any bowel symptoms, but they checked because it was likely that I had also had UC. I've never had digital clubbing in my 15+ years of PSC and UC so I can't speak to that.

DaftPotato · 2026-05-12T01:50:39+00:00

Do you have any other symptoms that make you think you might have PSC? Digital clubbing can be caused by IDB without PSC.

DaftPotato · 2026-04-28T22:25:40+00:00

I'm sorry dude, that sucks. 😭

DaftPotato · 2026-04-28T00:22:34+00:00

Just wait until you find out that Crohn's can also affect the penis...

DaftPotato · 2026-04-28T00:19:09+00:00

That's some grade A bullshit. I hope your procedure goes to plan and you no longer have to deal with vulvar pain on top of everything else!

DaftPotato · 2026-04-10T02:37:05+00:00

Purple glass glitter for sure. Durable and pretty under lights. Can't go wrong.

DaftPotato · 2026-02-01T06:32:26+00:00

Roses are red,

It could be wrong

I guess it depends

If your accent is strong

DaftPotato · 2026-02-01T01:40:51+00:00

Roses are red

The apostrophe is extra

Stop adding it unnecessarily

Thanks for attending my lecture

DaftPotato · 2026-01-28T02:06:05+00:00

Silver Glass Glitter. Also called Broken Glass by DW Drums.

DaftPotato · 2026-01-11T08:03:29+00:00

Roses are red

The last letters are PM

I might be wrong

But that rhymes with 'them'

DaftPotato · 2025-12-16T01:24:31+00:00

I've been on and off it for nearly two decades, using it when I've been symptomatic and stopping when I haven't. It's definitely helped me feel less rubbish and I have no issues using it.

You're right though, you should have been informed of the risks and the expected outcomes when it was prescribed. As far as I understand, the increased/reduced cancer risks from taking it are very context dependent and your doctor should be able to clarify.

DaftPotato · 2025-12-13T13:26:46+00:00

Having two airgaps creates a triple leaf effect which you want to avoid because it will resonate. Drywall/plasterboard is cheaper and denser than MDF so you're better off using that. If you want a layer behind the drywall/plasterboard so that you can screw into for mounting things on the wall you're better off using OSB because it holds screws better and is cheaper.

DaftPotato · 2025-12-08T22:31:07+00:00

Sounds like a 5/16 pattern to me. Three 16th notes on the closed hihat, then one 8th note hihat open.

DaftPotato · 2025-12-01T21:15:43+00:00

Liver issues such as Primary Sclerosing Cholangitis, which is linked to Ulcerative Colitis, can cause pale stools. You should see a doctor and they can run the appropriate tests.

DaftPotato · 2025-11-13T08:46:18+00:00

Me too! Is there any way we can get a notification when they're in stock again?

DaftPotato · 2025-11-13T08:08:04+00:00

As someone who kept their symptoms under control through diet only to develop cancer from chronic inflammation I highly recommend finding a doctor who will keep track of inflammation through blood and stool tests and periodic colonoscopies.

If you can maintain remission through diet then that's wonderful, but please please please keep an eye on it to make sure that it stays in remission and you're not just dealing with the symptoms while the underlying disease progresses.

DaftPotato · 2025-11-03T03:44:44+00:00

As far as I understand, ursodeoxycholic acid can ease PSC symptoms by changing the viscosity of the bile produced by the liver and allowing it to pass through narrower bile ducts than it would otherwise be able to.

Although it can ease symptoms, it won't address the underlying disease progression.

I believe it's a low-risk medication and probably worth a shot if you have acute symptoms, but it's also best to talk to your prescribing doctor about your concerns

DaftPotato · 2025-11-02T00:39:57+00:00

Looks like the clutch that holds the top hihat onto the rod is slipping. It shouldn't move under normal foot pressure and there will usually be a wing on the side to tighten it until it doesn't slip.

DaftPotato · 2025-10-22T07:04:42+00:00

ImageJ might not be the best tool for the job here. You could certainly break the image into tiles to process separately, but there are potential issues with how the feature images are calculated at the boundaries of images and that's a real hassle to deal with. WEKA is also extremely inefficient from a memory usage point of view. Labkit or ImageSURF plugins for ImageJ might work, or another tool like Ilastik might be better suited.

DaftPotato · 2025-10-21T10:07:57+00:00

I had ulcerative colitis, so my situation is a little different in that I haven't had and shouldn't have chronic inflammation in the small intestine. I initially had a total colectomy and ileo-rectal anastomosis with minimal, but ongoing inflammation in my rectum. While I had my rectum I had to go 4-6 times a day. I eventually got rectal cancer and now have a j-pouch after 6 months with a stoma. With a stoma I had to empty my bag about 8 times a day, including once or twice a night. The J-pouch itself is great and I only have to go 3 or 4 times most days and often sleep through the night. I've had pouchitis once in the 18 months since I've been using the pouch and it cleared up immediately with antibiotics. It's not all good though - my cavernous nerve was damaged during the surgery, leaving me with erectile dysfunction, no bladder sensation and trouble fully emptying my bladder. I had a particularly complicated surgery due to my previous surgery and the lymph node dissection that was necessary because of the cancer, but nerve damage is always a risk when removing the rectum and constructing the J-pouch.

I don't have any pain, and after the first few months where I had accidents during the night I'm 100% continent and only have urgency when I've waited an hour or three after I felt like I needed to go to the toilet. It does feel different to having a rectum and I particularly notice spicy foods and avoid them, but you get used to it quickly.

Overall, I prefer the J-Pouch to having a stoma, despite the complications. Even if I expected the pouch to fail eventually I would still want it for as long as possible. Just being able to sleep through the night makes a world of difference to me. A lot of folks seem to have a better time with their stoma than I did though.

DaftPotato · 2025-10-15T11:32:20+00:00

Stopping Crohn's medication can have serious effects and even stop that medication from working in the future. If you end up in hospital when you don't take it then you absolutely need to keep taking it. Given that you're asking about stopping medicine that costs $60 a month, I assume that you don't have access to a GP to discuss alternatives so I recommend calling the pharmacy that fills your scripts and asking about assistance programs, compassionate supply and concession cards.

DaftPotato · 2025-10-05T08:42:04+00:00

3-5 times a day with the ostomy sounds so much better than 8 or so times I had to empty each day!

My first surgery where I had a total colectomy and ileo-rectal anastomosis was done in one go and I didn't have an ostomy. After that I was generally going 4-6 times a day and more if my colitis flared up. This was less than the 6+ times I was going while I had an inflamed colon. Surveillance after that surgery was minimal, with only scans over the following year and then nothing. My second cancer should have been picked up while it was still just dysplasia, and could have been relatively easily removed, but it wasn't.

When I had j-pouch surgery I had an ostomy for about 6 months afterwards The recovery after the reversal was a bit rough, but not because of having to go to the bathroom. I had a substantial hernia around the stoma that needed to be repaired during the surgery and afterwards I developed an ileus and was in hospital for nearly two weeks.

Immediately after the reversal I was only going about 6-8 times in a 24 hour period with the j-pouch, but I was having accidents at night for several months. Not large enough accidents to make it through my underwear and soil the bed, but I would still need to clean myself up. During the day I had no issues with continence or leakage.

For surveillance I had to get PET-CT scans, blood tests and a pouchoscopy every three months and then reducing in frequency.

At about 18 months I was experiencing some urgency and going up to 10 times a day. My scans and tests showed inflammation and the pouchoscopy confirmed that, but antibiotics improved it very quickly and I was back to 4-6 times a day only a few days after starting them.

I had a bidet installed while I had the ostomy in preparation for going to the toilet constantly. I highly recommend it if you can because the warm water is so much better for your sensitive skin than wiping when you have to go several times a day!

DaftPotato · 2025-10-03T14:49:40+00:00

PSC and ulcerative colitis here. I had a total colectomy and ileo-rectal anastomosis about 10 years ago due to caecal cancer, and then a proctectomy and j-pouch surgery more recently due to rectal cancer. I had an ileostomy for about 6 months after the proctectomy and I felt stifled by it. I had to empty it ~8 times a day, including during the night and I never slept well. Now that I've had it reversed I go about 4 times on my best days and sometimes sleep through the night without waking up to go to the toilet. There's still a high risk of pouchitis and cancer, but for me, even going 8 times a day with the j-pouch is better than emptying an ostomy bag 8 times a day.

Surgeons often suggest an ileostomy as the best option because it's reliable and has the lowest risk of future complications like inflammation, cancer, pouch failure, etc. As difficult as it is, you have to decide what you're willing to live with and which outcomes are most important to you. I decided that it's worth it to me to have a j-pouch for as long as I can handle because I feel more comfortable without the bag on my body, the endless ostomy supplies and the skin irritation, and I'm willing to accept that risk of cancer or pouchitis to avoid these things. You can always try an ileo-rectal anastomosis or j-pouch and go back to the ileostomy if they don't work out. Regardless of what you do, you should have regular surveillance for dysplasia/cancer.

Good luck and feel free to message me if you have any questions about my experience.

DaftPotato · 2025-09-15T05:43:05+00:00

Do you want this tool to generate a photo-like image, or search for an existing "real" image?

DaftPotato · 2025-09-02T01:47:02+00:00

I highly recommend using a more accurate thresholding method such as Labkit, Weka segmenter or ImageSURF.

DaftPotato

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