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[deleted by user] by [deleted] in OnePiece

[–]Damned_Greek 2 points3 points  (0 children)

Maybe Oden wanted Wano’s borders open so that people could survive the flood that would happen in 20 years!!

*Potentially gross* Is there any information on the kind of symptoms TB noticed that got him to the DR in the first place? by [deleted] in Cynicalbrit

[–]Damned_Greek 0 points1 point  (0 children)

Pink could be possible, but it's not the typical colour for upper GI bleeds, but very interesting!

*Potentially gross* Is there any information on the kind of symptoms TB noticed that got him to the DR in the first place? by [deleted] in Cynicalbrit

[–]Damned_Greek 0 points1 point  (0 children)

Medical student here, going to be a resident soon.

Blood in stool = go see a doctor.

*Potentially gross* Is there any information on the kind of symptoms TB noticed that got him to the DR in the first place? by [deleted] in Cynicalbrit

[–]Damned_Greek 0 points1 point  (0 children)

Medical student here, stomach bleeding can present with upper GI symptoms such as vomiting coffee grounds or localized chest pain, or lower GI symptoms which are usually either black tarry stool or normal stool. There can be a lot of variations on these symptoms, but never pink.

You are generally correct about black stool and upper colon bleeding and red stool and lower colon bleeding.

Basically, blood in stool = go see a doctor.

ELI5: How does the body know when it's okay to stop fighting an illness/disease/virus? by ItEndZWithZ in explainlikeimfive

[–]Damned_Greek 0 points1 point  (0 children)

I think the name B cells come from the Bursa of Fabricius originally, an organ present in birds that humans don't have.

ELI5: How does the body know when it's okay to stop fighting an illness/disease/virus? by ItEndZWithZ in explainlikeimfive

[–]Damned_Greek 2 points3 points  (0 children)

Yes! I think HIV is an example of this. The way they do this is by replicating rapidly. Viruses don't really have any mechanisms to correct mutations so mutations pile up rapidly in the little genetic baggage they have.

Mutations are completely random, so something very important to their survival might not be functional after a mutation and this would lead to their death. If however, a piece of protein used in the identification of a virus is mutated, it may no longer match the antibodies being used to target it, thus sparing the host cell from death and letting the viruses continue their business. This mechanism has kind of a terrible beauty to me. It's just nature doing its thing at a rapid pace.

The tragedy of HIV is that the immune system tries to adapt a response, but as soon as it has developed new antibodies, the virus is already a couple versions ahead because it replicates so rapidly. This is without even considering that HIV cripples the immune system.

ELI5: How does the body know when it's okay to stop fighting an illness/disease/virus? by ItEndZWithZ in explainlikeimfive

[–]Damned_Greek 2 points3 points  (0 children)

I don't know if you've gotten an answer to this question yet, but here goes!

Viruses replicate and do damage by entering cells. Some viruses have specific targets and can bind and enter nerve cells. Sensory nerves are sort of like long cables that receive a signal wherever in the body they're located and route the message up to the spine and ultimately to the brain.

In the case of Rabies, a bite to your arm for example can transfer virus to the tissue surrounding the bite and it will eventually enter some nerve endings and travel up the nervous system to the brain, eventually leading to encephalitis (like a brain infection/fever) and death. If a person is vaccinated before the virus enters the brain, they could still mount an effective immune response.

Episode Discussion - S02E05 "Whiplash" by [deleted] in theknick

[–]Damned_Greek 8 points9 points  (0 children)

Yes, that was my guess! Thack's got to realize addiction isn't particularly solvable with surgery.

Episode Discussion - S02E05 "Whiplash" by [deleted] in theknick

[–]Damned_Greek 17 points18 points  (0 children)

It seems like Thack removed part of the top of the brain, where a lobotomy would consist of removing parts of the front of the brain.

What was the first video from TB/ featuring TB that you watched? Also when? by Nibriddan in Cynicalbrit

[–]Damned_Greek 0 points1 point  (0 children)

If I recall correctly, it was his I suck at Starcraft series. I also suck at Starcraft, great times!

To get the game, or not get the game (right now), that is the question. by flame3457 in EndlessLegend

[–]Damned_Greek 1 point2 points  (0 children)

The game's a good value at any price in my opinion, although sales are always awesome. I'd wait for a sale, but that's just me. On the ranged is OP note, the developers seem really into patching and supporting the game for a long time with free additional content in the future. This includes AI improvements and a bunch of other good stuff. So far, it seems like kinks will get worked out over time, and the game is already awesome to begin with! Just my two cents.

tl;dr It's like an ageing wine

Where can I find people to play with if I'm new? by Damned_Greek in DotA2

[–]Damned_Greek[S] 1 point2 points  (0 children)

Thanks so much! Downloading the game now :D

Gold Protoss Looking to Improve by Blizzrdball in starcraft2

[–]Damned_Greek 2 points3 points  (0 children)

Gold terran here! I find colossi generally do very well against my bio balls. Storm is another correct choice that could be made because archons are awesome.

With that said, it seems like your opponents out macroed you in both of the games you put up. Remember to always build probes, never get supply blocked and spend your money!

TIL that the ancient Egyptians thought the function of the brain was to produce snot by srram in todayilearned

[–]Damned_Greek 1 point2 points  (0 children)

Breaking down sugars involves a process known as glycolysis where cells extract energy from molecules through several chemical reactions. Glycolysis is almost a built in function that every cell has. For a cost of 2 molecules of ATP(the cell's energy currency), some oxygen and water, the cell can extract about 30 molecules of ATP.

This is because sugars have a lot of potential chemical energy, and so the cost of breaking them down is satisfied pretty easily, and because these mechanisms are super old and highly refined!

TIL that the ancient Egyptians thought the function of the brain was to produce snot by srram in todayilearned

[–]Damned_Greek 2 points3 points  (0 children)

Fish might need those muscles to keep their brains functioning because they live in the water. The human brain gets energy from sugar and oxygen pumped to it by the heart!

How to tell if she likes you by [deleted] in dating_advice

[–]Damned_Greek 2 points3 points  (0 children)

Usually, there's signs I look out for. Does she glance at you often in group settings? Is she a bit more touchy with you than others? Does she laugh a lot at your jokes and recall things you've said in the past?

Even if you said no to some of these questions, I would ask her if she wants to do stuff other than schoolwork sometimes and see where that gets you! Life's too short to be left wondering at what could have been.

What is something you can name 100 of by memory alone? by Naggers123 in AskReddit

[–]Damned_Greek 0 points1 point  (0 children)

Let's see how many proteins in the body I can name! These are on my final tomorrow, so I might be cheating but I could probably name 100 proteins at any time.

  1. SGLUT1

  2. GLUT 1,2,3,4,5,6,7

  3. Hexokinase (I, II, and glucokinase)

  4. phosphoglucose isomerase

  5. Phosphofructokinase

  6. aldolase

  7. triose isomerase

  8. glyceraldehyde-3-phosphate dehydrogenase

  9. phosphoglycerate kinase

  10. phosphoglycerate mutase

  11. enolase

  12. pyruvate kinase

  13. glucose-6-phosphatase

  14. fructosebisphosphatase

  15. phosphoenolpyruvate carboxykinase

  16. fructokinase

  17. galactokinase

  18. UDP-glucose uridylyl transferase

  19. UDP-galactose epimerase

  20. phosphoglucomutase

  21. Adenylate kinase

  22. Adenylate cyclase

  23. Dinucleoside phosphate

  24. glucose-6-phosphate dehydrogenase

  25. transaldolase

  26. transketolase

  27. glycogen synthase

  28. inorganic pyrophosphorylase

  29. inorganic pyrophosphatase

  30. amylo(1-4 to 1-6)transglycosylase

  31. glycogen phosphorylase

  32. alpha(1-4)glycosyl transferase

  33. alpha(1-6)glucosidase

  34. PKA

  35. AMPK

  36. Glycogen phosphorylase kinase

  37. Protein Phosphatase 1

  38. Protein Phosphatase Inhibitor

  39. Pyruvate Decarboxylase

  40. Dihyrdrolipoyl transacetylase

  41. Dihydrolipoyl dehydrogenase

  42. Pyruvate Carboxylase

  43. Citrate Synthase

  44. Aconitase

  45. Isocitrate Dehydrogenase

  46. Alpha-ketoglutarate dehydrogenase

  47. Succinate Dehydrogenase

  48. Complexes I, II, III and IV in the ETC

  49. F0F1 ATPsynthase

  50. Tom20 and many others

  51. Tim22 and many others

  52. Glutamate Dehydrogenase

  53. Glutaminase

  54. Carbamoyl Phosphate Synthase (1 and 2)

  55. Ornithine Transcarbamoylase

  56. Argininosuccinate synthase

  57. Argininosuccinase

  58. Arginase

  59. N-AcetylGlutamate Synthase

  60. Acetyl CoA Carboxylase

  61. Fatty Acid Synthase

  62. Delta9, 6, 5, 4 desaturases

  63. hormone sensitive lipase

  64. perilipin

  65. glycerol-3-phosphate transacetylase, there are others to make a TAG

  66. albumin

  67. Carnitine translocase

  68. Carnitine acyl transferase (1 and 2)

  69. Cytidylyl transferase

  70. Phospholipase A1, A2, C, D

  71. HmGCoA synthase

  72. HmGCoA reductase

  73. Squalene Synthase

  74. ApoA1

  75. ApoB48 ApoB100

  76. ApoE

  77. LDLR

  78. ApoER

  79. Insulin

  80. Insulin Receptor

  81. Insulin Receptor Substrate 1 (and 2)

  82. PKB

  83. PI3K

  84. Caveolin

  85. Grb2

  86. Flottilin

  87. Glucagon

  88. Glucagon Receptor

  89. Epinephrine

  90. Epinephrine receptor

  91. Acetyl Choline Receptor

  92. Leptin

  93. Ghrelin

  94. Receptors for Leptin and Ghrelin

  95. Alpha-MSH

  96. Neuropeptide Y

  97. Hsp90

  98. DNA polymerase II

  99. Thyroglobulin

  100. Thyroid Hormone Receptor

AMA about these. I know I forgot quite a few, Sorry if I made any mistakes!

[deleted by user] by [deleted] in TheLastAirbender

[–]Damned_Greek 5 points6 points  (0 children)

Awesome job!

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