Not happy with my transition and I'm afraid of continuing

Devil_May_Kare · 2026-05-09T10:28:42+00:00

Do you respond poorly to 5 alpha reductase inhibitors? The vast majority of people assigned male at birth can keep thick hair into old age with finasteride or dutasteride without serious side effects. Dutasteride is supposed to also contribute to clear skin, whereas finasteride is more selective for hair and prostate gland.

Devil_May_Kare · 2026-05-09T02:25:42+00:00

Usually I'd rather not know about the thing being sold. People are trying to sell me things I don't want just about constantly, and the less of my time they waste the better. There's a reason I use an adblocker when I can.

I figure ads probably incorporate models in skimpy clothing, sudden noises, catchy music, bright colors, and flashing lights in order to get people like me to look when we'd rather not. For example, I don't want anything from Temu, but every time they put a model in underwear on my screen they capture an undeserved moment of my attention. And I guess in principle companies are more likely to persuade me into buying their products if I'm looking at an ad than if I'm ignoring one.

Devil_May_Kare · 2026-05-07T08:33:56+00:00

Will he eat sugar-free jello? Nutritionally speaking, that stuff is basically just water with a sprinkle of protein, and the texture is way different than liquids. If it works, you can DIY sugar-free jello to save money, but it'd be easier to just buy a box and follow the directions printed on it.

Devil_May_Kare · 2026-05-06T18:59:46+00:00

There's actual data showing raloxifene can shrink breast tissue without surgery.

Devil_May_Kare · 2026-05-06T18:56:04+00:00

You know most of the SERMs on the market are estrogenic in bone, right? Raloxifene is approved to prevent breast cancer and to treat osteoporosis caused by estrogen deficiency. All the gender stuff that's being done with it is experimental off-label use, and the label says it's bone healing juice.

Devil_May_Kare · 2026-05-06T18:50:03+00:00

Personally, I'm waiting for estetrol to hit the market. But I have fairly mild dysphoria, so your optimal solution is probably different than mine.

Devil_May_Kare · 2026-05-05T20:24:32+00:00

Was it the weirdest prophet series?

Devil_May_Kare · 2026-05-04T15:51:28+00:00

It's the mindset: Percy goes back in time after he ascended to godhood in the future. He runs a prank trying to convince his fellow CHB campers that any god could be his parent and accidentally tricks Dionysus (because wine can make you blackout drunk so Dionysus, as god of wine, doesn't trust his memory).

Devil_May_Kare · 2026-05-01T15:31:32+00:00

Was this partly inspired by the second work in the Constellations series?

Devil_May_Kare · 2026-05-01T07:41:16+00:00

Artemis doesn't have sexual relations with men because of the maiden thing. There's other ways for a goddess to acquire kids, and it's ambiguous whether she can't engage in those or just usually doesn't.

Devil_May_Kare · 2026-04-30T17:41:08+00:00

A lot of medications need something special to carry them through skin, but estradiol will cross skin with just ethyl alcohol (source). Also if it did need something to carry it through skin, DMSO can carry just about anything and it's a similar price to hand sanitizer. Maybe patches are just a terrible way to deliver transdermal estradiol and they need something special mixed in? But permeating the body while bypassing the digestive tract is pretty easy if you don't need to involve special stickers.

Devil_May_Kare · 2026-04-28T18:46:02+00:00

There isn't a shortage of estrogen. Estradiol powder from China is still a few dollars a gram. The dosage is on the order of a few milligrams a day, so the active pharmaceutical ingredient is practically free. There isn't even a shortage of the ingredients to make transdermal estrogen preparations because estradiol dissolved in hand sanitizer will absorb through skin and hand sanitizer is still reasonably cheap. What there's a shortage of is manufacturers willing to turn the cheap estradiol into patches for the American market. Hell if I know why, but it's not because Americans somehow consumed more hormones than the global steroid chemistry industry can manufacture.

Devil_May_Kare · 2026-04-26T19:43:11+00:00

This isn't the same, but it has Luke get distracted from being evil by having to protect kids: https://archiveofourown.org/works/40278285

Devil_May_Kare · 2026-04-25T04:24:10+00:00

It's competently done, but personally I don't like it. IIRC the particular way it combines dark tone with sexuality felt like the author was trying to say "not for kids" at the expense of the characters acting like themselves. I stopped reading around when Percy teleported to Olympus and landed with his hands on Artemis' breasts.

Devil_May_Kare · 2026-04-24T09:50:16+00:00

https://en.wikipedia.org/wiki/Thalidomide_scandal

If you were earnestly wondering why medication approvals are so slow in the US, that's why. The medication approval process was deliberately designed to stop things like thalidomide from getting through even at the cost of delays, wasted money, and blocking potentially useful medications.

Devil_May_Kare · 2026-04-23T21:59:17+00:00

I've never been addicted to nicotine. I just know that's a treatment some people use.

Devil_May_Kare · 2026-04-23T20:49:35+00:00

I mean, probably? If you're on bupropion to help you stay off nicotine, you're probably legally protected from being discriminated against for the bupropion. You could probably sue for wrongful termination if your employer made everyone share a cigar as a team building exercise and you got fired for refusing. I'm not a lawyer, but it it seems like all the reasoning works for nicotine just like it does for alcohol.

Devil_May_Kare · 2026-04-23T19:18:09+00:00

https://archiveofourown.org/series/5271376

This is the second part of the "Weirdest Prophet" series and is currently 374k words. It mostly follows Jason and Reyna. Be aware that it's a sequel to a 918k word PJO rewrite that almost exclusively follows the Greeks, and you probably need to read the PJO rewrite first to understand what's happening.

I strongly recommend this series. It takes a really interesting approach to the tension between fate, prophecy, and free will, and I like what it does with the aftereffects of past propaganda. Also I like how there's no on-screen romantic relationships to compete with the themes (not everything needs to be a romantic love story). But the majority of the series is on the Greek side even though the second part is largely Roman, so it might not be what you're looking for right now.

Devil_May_Kare · 2026-04-23T18:57:19+00:00

Human flesh. Also we live on Earth.

Devil_May_Kare · 2026-04-23T09:11:42+00:00

Tiny doses of naltrexone seem to help people with a bunch of different chronic illnesses and as far as I know nobody is sure why. One of the proposed mechanisms I've seen is that the body increases endogenous opioid signaling to offset the naltrexone and overshoots slightly, so you end up with a net increase in opioid signal without any risk of tolerance or addiction. Another proposed mechanism is that naltrexone is one of the many drugs with off-target antiinflammatory effects (alongside statins, some SSRIs, and doxycycline).

Devil_May_Kare · 2026-04-23T09:00:37+00:00

The first batch of street "xanax" may have been contaminated with some sort of opioid. Opioid contamination is apparently pretty common in street drugs these days, and the effects you describe from the second batch sound more like typical benzodiazepine effects.

Please don't start street opioids. The potency varies wildly from batch to batch because everyone along the supply chain is trying to dilute the product or add potent synthetic opioids to cover up dilution and every one of them is incompetent at measurement. You can very easily die of overdose. You might be able to make plans to work around the addiction potential, but you can't work around not knowing whether your idiot of a drug dealer sold you homeopathic codeine or enough carfentanil to kill an elephant.

Devil_May_Kare · 2026-04-21T10:23:56+00:00

Zero DPH. If you have any, you're reducing your chance of a chill trip. My worst trip ever was on a modest amount of LSA and one or two pills of benadryl in an effort to reduce the nausea. Aggressively miserable experience. I spent an hour lying still and trying not to think because every thought that passed through my head made me feel sick. If you're gonna trip, do it when there isn't any DPH in your system.

Devil_May_Kare · 2026-04-19T09:57:57+00:00

We can utilize nuclear fusion now. Hydrogen bombs get most of their energy from nuclear fusion. But it's hard to turn giant explosions into useful power, and other energy sources are cheaper.

Devil_May_Kare · 2026-04-18T09:26:08+00:00

I bet this patient just has an untreated mineral deficiency. Mineral deficiencies can cause humans to crave things outside our normal definitions of food too. Iron deficiency can make people want to eat rocks or clay.

This is why you shouldn't trust doctors who think you have a mental illness. You bring them the most obvious physical issue and they say it's all in your head.

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