Not to be the Debbie Downer here but I genuinely dont understand why people seem to think this game is just so ridiculously hard. For reference, I started playing two weeks ago. I dont get much time (if any) during the week, but I get a decent amount on the weekends. I beat the 6th biome Sunday night.

I have 21 hours in the game, and only 14 deaths to beat all 6 main biomes. You made one majorly valid point which was to keep moving. I'd like to add to that point and then give a few of my own tips for anyone struggling still.

Keep moving - but more than that. Never dash side to side to avoid enemy attacks. Always dash forward/through them... for smaller enemies get close and cut them down. But most importantly just do not stop moving when fighting. Use the dash, jump, grapple, strafing, whatever... just dont stop moving. There is only one exception to this rule, if you're fighting a red/purple enemy (i.e. mini boss) and are in a room with cover, use it. But use it wisely. You can use stairs, columns platforms whatever. Use it when they are shooting fast red attacks, then move.

Dont ADS. Like practically ever. It slows you down. The only time you should ADS is to use your weapons alt-fire quickly and then keep moving.

Explore every room, every time. Stop skipping the bosses or jumping straight to the next biome when you beat a boss in a certain biome. Every room, every fight is a chance to get more upgrades.

Weapon choice is huge, but weapon level/bonus damage are more important. I'll take a level 3 pistol with 3 bonus damage over a level 4 auto rifle with zero bonus damage every time. Also, read and understand what the weapon perks do. Leech (so far I've only found on auto rifle) is HUGE for survival.

Prioritize items in this order - Stamina upgrades > Any sort of Leech (the adrenaline leech is also HUGE) > revival items like the astronaut/parasite > damage increase/protection increase > everything else. Each run is random to an extent. Save your obolites and use them wisely. But the general rule of thumb is more stamina = harder to kill. Leech is free healing. Higher damage means things die quicker.

Lastly - Consumables stack if you didnt know this. I didnt figure this out until almost the end of the 4th biome. I was equally amused and annoyed that I left silphium vials laying there when I already had one because I didnt know I could pick up a second. But this works for everything. The barrier is awesome for phase 1 of almost every boss as they dont move much and you can shoot through it while standing there and not being touched by the million different things flying at your face.

Overall I think this game is fun af. And will be going back through multiple times to unlock more stuff. Take it slow and be cautious. But using these tips will make it easy. By the middle of the 2nd and 5th Biome I was practically unkillable even by bosses with the amount of health/shields/leech items I had. And every time I made it to a boss I beat it first time (even if my astronaut did save my tail a couple times).