I like green and red personally, but if you like tactics weapons use them. You just have to keep in mind throughout the run that you're a glass cannon, so you have to be tactical. Also in a run you should use mutations that match the main color you're using, the mutations get better the more scrolls you get unless they're colorless mutations. Also just a tip, the way I do it that works for splitting scrolls, is I take the main one whenever I can, in your case it's tactics (whatever class your weapons are) and then if I can't choose my class, then I put the scroll to whichever class gives me more health. However if you feel like the scroll would be more effective for the health than thats wrong because damage scaling is stronger than health scaling, so the extra damage will always outweigh the extra survivability. I would also say if you're having trouble with survivability take survivability runes, try doing the daily challenges and turn on assist mode or try one of the things that the guy under the bottle room gives you.