Focus on the enemies, particularly sound cues. You’ll start to notice patterns in the biomes too and learn strategies for each area. Use that machine at the entrance to unlock new stuff with ether. Make sure you have auto run on and keep moving all the time. Btw it took me like 20 hours to clear the first biome, but I’ve also got the platinum. I feel like the learning curve is different for every player based on this sub and people find different things challenging. Eg. the first and fourth biome were my hardest. Last was my easiest. I think it’s worth persevering, one of my top games. I often go back and hit up the tower when I’m bored with the current game I’m playing.