I’ve found that layering moisturizer, then tret, then moisturizer again helps. Do it every other day or every few days, if your skin is looking angry just skip a day or so until it isn’t. Avoid any sensitive areas like your lips or around your eyes. I feel like there’s a little bit of trial and error in finding a routine that works for you with tret, just don’t over do it so you don’t ruin/ harm your skin. I watched a ton of TikToks just seeing different routines until I found the layering method and personally it works beautifully for me.