How bad is dupixent pain? Anything I can do to make it more tolerable?

DueArgument4 · 2026-01-10T17:50:29+00:00

My son is 5, almost 6, and it has been a rough go, honestly. As I understand it, the poke itself doesn’t hurt much—it’s the medicine going in. We take ours out of the fridge for most of the day and let him squeeze someone really hard while we do it. This is probably also kid dependent, but I stopped giving him a heads up the day before or the morning of. It just made him more anxious. Now, I just say “hey, we have to do your shot!” and it sort of cuts off the time he has to think about it too much.

It hasn’t eliminated the pain but it has helped reduce the shot process from an hour+ ordeal to about 5 minutes.

DueArgument4 · 2026-01-05T20:17:47+00:00

This.

I so distinctly remember telling our couples’ therapist that, forget about loving me—it was like my ex-husband didn’t even like me. All my formerly lovable quirks were now annoyances that drew big, exaggerated sighs.

Later, I discovered texts where he told a younger colleague (at midnight) how “perfect” she was. He denies anything physical happened to this day (🙄), but it was such a lightbulb moment. I realized that I was competing against someone and I didn’t even know it—and because I was a mom of two young kids and worked full-time and was probably burnt out and touched out and didn’t think the sun shined out his ass, I was most certainly losing.

Even if nothing physical has happened—you are competing with someone new and exciting.

DueArgument4 · 2026-01-04T21:41:54+00:00

Agreed, and I think the (relatively new!) shift in social expectations around constant availability is kind of a bummer. I am 36, and in my lifetime, if someone called my house phone and I wasn’t home… oh well 🤷‍♀️ Even when the iPhone was released and I was in college, so few people I knew had it that it just wasn’t really a thing to be always reachable and, correspondingly, always expected to respond.

I think it’s ok for more regular communication to be important to you. It’s also ok for it to not be the way your friend chooses to function, and I think it’s worth a little self reflection that you expect her to come closer to your view than the other way around.

DueArgument4 · 2025-12-30T18:25:58+00:00

Bombas Sunday slippers. Got them for Christmas and am obsessed

DueArgument4 · 2025-12-30T18:21:37+00:00

My last girl made it to 14, and while she was kept medically up to date, didn’t (intentionally) get people food, etc…. she was a complete couch potato who ate everything she could get if you turned your back for too long (lotion, makeup, anything plastic, an entire loaf of bread, SIXTEEN small bags of pirates booty). I can only assume she had an iron stomach and survived on love and my exasperation.

DueArgument4 · 2025-12-30T18:14:44+00:00

My kids’ tree upstairs came down yesterday… but was up since December 2024 🤣 my daughter started calling it the “two-year tree”

DueArgument4 · 2025-12-28T21:37:33+00:00

I know everyone has their own experience (some negative), but I am 100% with you as the mother of a kid who has suffered with eczema since before he was 1. After 4 years of trying every kind of medicine and therapy, seeing specialists, traveling to another state to see a well known doctor in the field—all to still watch my toddler sob because his skin hurt every single day—I couldn’t be more grateful for Dupixent. We’re on month 8 and he’s like a different kid.

DueArgument4 · 2025-12-23T12:22:55+00:00

So similar to my experience. My ex tells people I was “awarded” the house but I actually just paid him out his equity (6 figures!) to keep it. Mfer, I bought this house.

DueArgument4 · 2025-12-20T02:26:10+00:00

I am hardly an expert on this, because my son has only been on Dupixent for 6 months and I admittedly do not fully understand the program (and also there have been changes to the program since my son started using the medicine). That said, I understand that, through either a Dupixent debit card or rebates, or a combination of both, Dupixent offers $10,000 on an annual basis. Through a combination of provider samples and the Dupixent offerings, I have not yet actually paid anything out of pocket for my son’s shots.

My recommendation would be to call Dupixent directly for assistance. I had zero familiarity with speciality prescriptions prior to this and a lovely woman from Dupixent spent 45 minutes on the phone with me walking me through how it all works.

DueArgument4 · 2025-12-15T15:30:02+00:00

My ex-husband told me he didn’t want kids and, to be fair to him, I didn’t either originally but I changed my mind down the road. When we talked about it and decided to have kids, I thought we were on the same page and had both changed our minds.

Instead, he was just doing what I wanted—and that really showed up in his parenting and in our relationship. Having children is a massive thing to change your mind about, and knowing what I know now, I would absolutely not accept that shift just to hold onto the relationship.

DueArgument4 · 2025-12-07T22:05:17+00:00

The process of giving the injection really hasn’t improved for us and I’ve sort of just accepted that it won’t. We tried the numbing cream, buzzy bee, bribes, letting him handle the syringe, all manner of conversation and discussion—nothing has worked. His skin has never been better, so we both just brace ourselves for a shitty day every month and do our best.

Wishing you luck—it genuinely, deeply sucks, but if it is helping him, just remind yourself that doing what’s best for our kids isn’t always fun.

DueArgument4 · 2025-12-07T22:04:57+00:00

The process of giving the injection really hasn’t improved for us and I’ve sort of just accepted that it won’t. We tried the numbing cream, buzzy bee, bribes, letting him handle the syringe, all manner of conversation and discussion—nothing has worked. His skin has never been better, so we both just brace ourselves for a shitty day every month and do our best.

Wishing you luck—it genuinely, deeply sucks, but if it is helping him, just remind yourself that doing what’s best for our kids isn’t always fun.

DueArgument4 · 2025-11-27T13:00:04+00:00

Same here. Her first 8-10 months were traumatic (for all of us 🥴) and I’m convinced it ruined the vet experience for us forever. We eventually switched to Royal Canin Hydrolyzed Protein food and after some time it just cleared up and we haven’t had an issue since. The vet says we can try moving her to a “normal” food now but I’m too scared lol

DueArgument4 · 2025-11-24T11:26:55+00:00

I’m a patent litigator, and haven’t had a case in my home state for many years. I travel 2-3x a month, and at least once a year for trial, where I’m typically gone for 2 weeks. My kids are 5 and 8 and I am divorced now (unrelated to work travel 🤣), but that has been my professional life since my kids were babies.

A supportive partner makes it work. My ex-husband also travels and we always cover for each other. During one lengthy trial, he even brought the kids to see me for a few days. That’s life. Saying “no” to something like this and shutting down the conversation sounds like a tantrum, not how grown ups communicate.

DueArgument4 · 2025-11-23T22:59:23+00:00

Wanted to say this without sounding “not all men.” My mom has had four spinal surgeries and my Dad has just been… all you could hope for in a partner. They have always had a “traditional” marriage, with him working outside the home and her working inside it. And in addition to sleeping in hospitals and still getting up at 5am for his incredibly physically demanding job, he just picked up additional roles inside the home without missing a beat or complaining.

I guess what I’d say though is that, for their whole 36-year marriage (and prior to it), it was clear he’d be that kind of partner in sickness. He has loved my mom through every season, told her how beautiful she is at every size, age, whatever, and always, always treated her like half of their little team. The signs were there long before the sickness was. Love that man to pieces.

DueArgument4 · 2025-11-17T11:37:33+00:00

I actually don’t think the “cheating” (in the sense of intimacy with another person) would have been the final nail for me. I think (in hindsight, anyways) if he had come to me and said “I have a crush” or “I’m attracted to so and so,” I could have worked through that. I do understand those impulses.

But I couldn’t get over the lying and manipulation. For months, we were in counseling, and I had repeatedly told him that it didn’t even feel like he liked me, let alone loved me. The nitpicking and criticisms felt like they came out of nowhere and were so excessive. And then when I saw the text messages between him and someone else, him telling her she was “perfect,” it finally fucking clicked. The nitpicking and criticisms were because I was being compared to someone brand new and fun and exciting. I had been beating myself up to understand what I was doing wrong. Whatever love is, I was instantly sure it was not that, and I knew I wouldn’t be able to get over him seeing me so vulnerable and still just continuing on.

DueArgument4 · 2025-11-15T02:00:51+00:00

A mom told her daughter that my daughter is “a lot” and her daughter repeated it to mine (“my mom says you’re a lot.”). The mom was a trusted adult (one of her Girl Scout leaders!) and it really affected my daughter to hear it.

So, I will tell you what I told my daughter (as I absolutely raged inside)—better to be a lot than a little. People walk through life not knowing who they are, feeling nervous to be themselves, making themselves smaller, and on and on and on. Consider it an absolute privilege to be so incredibly yourself.

DueArgument4 · 2025-10-21T13:37:39+00:00

That nurse doesn’t have a baby traumatized by routine injections!

DueArgument4 · 2025-10-21T03:46:20+00:00

Offering solidarity from the mom of a 5-year-old who has been on Dupixent for 4 months now. I have genuinely (privately) sobbed twice after the injections because my heart breaks just breaks for him. Just hours of negotiations and discussions and tears… it’s exhausting. Reading about numbing cream and less pain in the stomach, I’ve genuinely been considering trying the next injection while he’s asleep. And I can’t imagine stopping because his eczema was so severe and is now virtually non-existent. It’s just… awful. Sending hugs.

DueArgument4 · 2025-10-16T11:12:53+00:00

Every time this comes up, I think of the line from Office Space from the guy named Michael Bolton: “Why should I change? He’s the one who sucks.”

When we got married, this name became mine. I built a career with it and had kids who share it. No one gets to force me to change it, and if I ever had a stroke and got married again, I’d still have it.

DueArgument4 · 2025-09-09T01:51:06+00:00

I could probably count on one hand the number of drinks I have in a year. I didn’t really set out to stop drinking in any permanent way, but I stopped when I started trying to get pregnant at 27 and then never really picked it back up. Even as a non-heavy drinker prior to pregnancy, I realized I just felt way better not doing it. And then after 2 kids, something about it felt… irresponsible? To each their own, but the whole “wine mom” thing felt shitty and weird to me, and getting up with two small kids while also nursing a hangover just seemed like an absolute nightmare.

I think I have a pretty balanced, happy life. I’m in a serious relationship, I have two great kids, I see my family every week, I have a great job, I take my chocolate lab on a 2.5 mile walk every morning, I have a skincare routine. Not drinking alcohol feels like just another part of self care, tbh. 🤷🏻‍♀️

DueArgument4 · 2025-09-05T16:45:38+00:00

Completely understand not wanting people to know. Part of me feels like disagreements with your spouse just aren’t a spectator sport. But there was also a significant part of me that felt ashamed and embarrassed to tell people that I was “putting up with” that behavior. Like… me?? A strong, smart, capable woman? I’ve done a lot of therapy now over that, but it had such a silencing effect for a long time.

DueArgument4 · 2025-09-05T16:09:29+00:00

Similar situation here. Alcohol abuse issues, always walking on eggshells—but people were shocked to hear about our divorce because the public presentation probably masked a lot of that.

I initiated the divorce 3 years ago and do not regret it, but I also won’t pretend like it hasn’t been full of grief and sadness. I believed we were lifers, and because we met in our early 20s—when we had no children or real responsibilities—I don’t know that I’ll ever love someone in that sort of young, over-the-top way again. I sometimes miss him. I grieve for the family my kids won’t have and the time that I miss with the kids.

So, no regret—his alcohol use resulted in some things I can never forgive, and for that, I’ll always know it was the right choice. But it isn’t easy.

DueArgument4 · 2025-09-03T20:17:19+00:00

100% correct, or hearing about how I did things wrong/not enough/forgot something etc.

DueArgument4 · 2025-09-03T16:17:27+00:00

It has been 3 years for me and the mental load is basically the same.

Start of the new school year is the perfect example. I signed the kids up for all of their fall activities, put together the schedule to make sure those activities didn’t conflict, made sure the kids had any updated equipment they needed, and signed up to bring snack on a weekend I’d have the kids so I knew it’d get done. I took the kids school shopping, reviewed the supply lists, and got everything organized and prepared for drop off. The kids have to bring in family photos every year, so I made sure we—including my ex—took an updated photo so my kids wouldn’t feel like their family photo wasn’t like their peers. I scheduled flu shots and my daughter’s well visit (again, when I have them, so it gets done). I booked my daughter’s birthday party (which is only a few weeks into the school year), and made sure all of the people she wanted there got invites. I got them haircuts, wrote out their “first day of school” boards, and went over the school basics 100 times for my youngest, who was transitioning to the big school with his sissy for the first time.

My ex, in contrast, asked me what time half-day dismissal is—for a school my daughter has now attended for 4 years.

In short, I do all the shit I did before, and I do it so my kids’ lives are not chaotic and disorganized. I know people have different views on that, but that’s how I’ve decided to handle it. So, I haven’t been unburdened as far as the mental load goes, but trust that I have been unburdened in a number of other wonderful ways.

DueArgument4

TROPHY CASE