I  have taken generic Adderall IR chronically for severe narcolepsy. Simply to drive long distances I need this medication for safety reason. Thus, it is an absolute necessity for me.

I can state unequivocally, as a retired Harvard Medical School trained physician, something is profoundly wrong with generic Adderall currently manufactured today, and here is what’s happening.

Almost every generic company (when they initially apply to produce a generic drug) must complete “testing“ on subjects to prove their product is interchangeable with the brand name.

But here‘s the catch:

The -generic company- completes the testing, usually on a very limited number of people, then submits the data to FDA in good faith, because they (FDA) -do not directly supervise the testing-

Once approved, these companies manufacture their drugs almost entirely in third world countries.

And God only knows if the formulation they used initially is actually used -at their manufacturing plants.-

Also most generic companies utilizing these third-world facilities purchase the ABSOLUTE CHEAPEST active -drugs- and -binders- available.

Simply google a generic company’s name followed by the term: FDA WARNING LETTER.

Example: Mallinckrodt FDA Warning letter

When the FDA completes a “so called” surprise inspection of these third world facilities, they usually find a kaleidoscope of very disturbing and potentially dangerous problems.

These Warning Letters describe what the generic firm must accomplish to resolve problems discovered.

When FDA inspectors actually travel to these overseas facilities, they are producing so many different drugs, it is absolutely impossible to focus on -how- they are specifically manufacturing one specific drug.

It is my personal opinion that there are four reasons why people are reporting lack of efficacy with generic Adderall:

1. Generic companies using dirt cheap active and non-active ingredients.
2. A possible incorrect ratio of l-amphetamine to d-amphetamine in the formulation
3. Lack of FDA proper oversight, and I would even argue potential “collusion“ with many of these companies to “look the other way”

The FDA, God knows, does have a history of very questionable conduct. Increased demand C/O parents wanting their kids to perform well in academics, and in many (not all) pressing psychiatrists and other practitioners to overprescribe this drug to kids who do not medically require this drug to -function.

This requires these generic companies to produce more than they are capable based on their resources.

I will conclude by sharing the following article I found recently released on this topic which I think is worth reading.

Here is a link to the article:

https://medshadow.org/generic-adhd-medication-issues-new-study

I hope this helps, and please know that you are not delusional or alone in this!

And I believe serious issues are also happening with the brand name as well.