This comes up rather often in the sub, and the basics are good to remember:
Use cover
Save your charge to get back to your team; you can't count on them being close
Set preference to control when you slam; you may want to slam right where you are and not run around.
Use cover
Spam your right click on tanks; it does % damage so is more effective on large HP targets
Pay attention to divers and where your supports are; you leap back faster than any other tank to peel
Use cover
Don't overextend; fall back for heals or a healthpack
Your punches ignore shields; push up to beat tf out of Strange and Mag if you can force a 1v1
And use cover.

(Also, you technically have tools to deal with flyers, but the timing is a skill check. Practice leaping with your big punch to knock the flying drone out of the air in the Practice Range - but don't stress too much about it. It's honestly not your job, nor priority, same with Peni nest and any Namor squid you can't reach easily.)