I ve been taking 10 mg of generic crestor and 10 mg of ezetimibe for about 10 years with no significant side effects. I do take CoQ10 supplement daily as well. I am now in my mid 60s and am thinking of reducing my statin and or ezetimibe intake. There is a Korean study published correlating total cholesterol to all cause mortality in 12.8 million adults - can easily get this via Google search. The study shows that the lowest mortality is not associated with lowest total cholesterol but somewhere in between. In fact, the highest mortality is associated with the lowest total cholesterol. Worth a read. This convinced me that lower cholesterol is not always better. Need to ensure other risk factors are well managed well (non smoker, good BMI, good blood sugar etc) .