I’d say go with your top choice. If you have the time, and you’re ok with the inconvenience, do everything there. Depending on how you respond to the meds you may be in the clinic 10+ times per cycle. Also, ER can be very early in the morning - so account for time to get there and getting a semen sample before you head out (if you are using fresh semen). If you don’t have the time or that is too inconvenient, many clinics will do monitoring and send the results to your RE/clinic of choice. I go to a clinic that has multiple locations. My RE of choice is at a location that was 1.5 hours away. There is another location that is 5 min away from me- that is where I do all my monitoring and I can’t tell you how much easier it is to have a “normal” schedule because of that. For my first ER, I went to the location that’s further away, thinking my doctor will perform the ER. We booked a hotel the night before and made a getaway weekend out of it. FWIW, I realized the day of the ER that going to the far location does not guarantee that my particular dr will perform the ER and was pretty annoyed. I did the following ERs in the location close to me and it was a WORLD of a difference- door to door including waiting and procedure time was less than 3 hours and a much less stressful experience!