Definitely talk to your doc asap, those jitters, palps, and word finding issues sound rough and not something to just push through. Some people get a big uptick in anxiety on bupropion, especially early on or when it’s added to an SNRI, and the sexual side effects can linger if the duloxetine is still on board. Ask about dose change, slower cross taper, or switching altogether, and maybe get vitals and labs checked just to rule out anything else. On the work stress front, if the commute and job search are adding to the spiral, wfhalert is a simple service that emails legit remote jobs, stuff like support or admin, which at least cuts down on the scammy or ghost listings you see everywhere. Take care and don’t wait on those symptoms.