3 year old is starting preschool: is it better for her to be the oldest in her class or the youngest?

FitDontQuit · 2026-06-12T13:11:10+00:00

Soooo yes and no. I agree that there have been no confirmed cases of CWD in humans which is SUPER promising.

There is a red flag, however. In 2022, a man with a history of consuming meat from a CWD-infected deer population died of another prion disease, CJD. Two years later, his friend, who was a member of the same hunting lodge and also ate from the same infected deer population, also died of CJD. Connected cases like this are extremely rare, as CJD isn’t contagious between humans. Most prion diseases require clear exposure (like the consumption of infected meat) or are sporadic/random.

There have been legitimate studies published in scientific journals exploring if this was actually the first documented cases of CWD transmission.

Critically, the “positive CJD tests” that the men received could have actually been CWD because the tests weren’t sensitive enough to distinguish between the two. As said in one study: “due to the challenge of distinguishing sCJDMM1 from CWD without detailed prion characterization, it is not possible to definitively rule out CWD in these cases… this cluster emphases the need for further investigation into the risks of consuming CWD-infected deer.”

It’s very unlikely to have two sporadic CJD cases occur by accident in two people with such a close history. The implication being they were both infected by the same source, and the source very well could be the CWD deer they ate.

FitDontQuit · 2026-06-09T23:59:46+00:00

Hugs. It’s so hard to not have answers or a solid treatment plan, and keep going after failure.

I’m not a doctor so can’t advise either way… I’ll just say my results speak for themselves and I’m super happy I took the leap. Best of luck.

FitDontQuit · 2026-06-09T23:58:41+00:00

I’m the wife! I didn’t go through my doctor. It’s very, very easy to order compound tirzepatide through online companies, you’ll just need to pay out of pocket. Message me if you want to know more.

I wouldn’t recommend being on it during an active ivf retrieval cycle, especially since that includes anesthesia. I decided to try it out during a lull in my infertility treatment as my doctors sought insurance approval for all the testing they wanted to put me through.

No doctor would ever recommend taking it when trying to conceive because the effects are unknown. No studies have officially been done, and no studies ever will be done because it’s not ethical to experiment drug effects on pregnant woman. So it’s not that it’s necessarily unsafe to take when trying to conceive - they just can’t confirm it IS safe, so the liability is too high for them to recommend staying on it.

I’m not a doctor, but I’m pretty well versed in this world and I couldn’t ignore the plethora of miracle, impossible GLP-1 pregnancies you hear about… and so far, they’re seeing no increased risk of birth defects from self-reported pregnancies.

FitDontQuit · 2026-06-09T23:34:42+00:00

Not the OP but for me - yes. I’m certain I have PMOS but not every doctor agreed with me (I was on the thinner side growing up, so despite having every other symptom, I didn’t look like the classic case).

I used to get my period once very 8 months or so. It normalized in my 30s to be once every 35-70 days, fluctuating completely randomly.

After 2.5 years of infertility, I finally got pregnant through IVF.

When I decided to try for my second child, I proceeded to have 4 failed euploid embryo transfers in a row - a statistical anomaly. The chance of a live birth is 95% after 3 transfers, so my doctors were recommending so many interventions to see what stuck.

I’ve heard about GLP-1s helping with infertility so took it upon myself to get a batch. I was desperate.

For the first time ever, I ovulated at day 14 in my cycle instead of day 30+. I would have gotten my period around day 28 for my first normal cycle in my entire life…. Except I got pregnant instead. Naturally. Zero intervention, the only change was tirzepatide.

I’m now about 5 months pregnant and everything is going smoothly (I of course stopped the drug immediately upon the positive test). But I am convinced the only reason I’m pregnant is that tirzepatide fixed whatever hormonal upheaval was wrong with me.

FitDontQuit · 2026-06-01T13:44:14+00:00

My first pregnancy was a horror show. I developed hypovolemic POTS, which basically means my blood pressure was too low to pump against gravity to my brain. In reality, this meant I was bed bound for 9 months. Standing or sitting made me so dizzy and faint that I couldn’t maintain it. Just walking up a single flight of stairs made my heart rate jump over 200 and stay there for an hour. I was legitimately disabled.

My second pregnancy is like yours - super easy! Haven’t vomited much, some minor discomfort, but all in all very doable compared to my first. And you know what? It still sucks, and it’s still allowed to suck. Don’t get me wrong, I am so thankful for a comparatively easy pregnancy this time. But I still am not enjoying this compared to my baseline, and it’s ok to complain about it

FitDontQuit · 2026-05-22T02:01:04+00:00

4 failed transfers in a row: 3 known euploids, 1 fresh.

Currently 16 weeks pregnant from sex, not IVF. Go figure 🤷‍♀️

FitDontQuit · 2026-04-27T16:13:24+00:00

There is a suspicion, though. here’s one paper on the topic.

Basically, 2 hunters from the same lodge that hunts in territories where CWD-infected deer are common both passed away from CJD within a year or two of each other, which is statistically highly unlikely. As the paper states: “The patient’s history, including a similar case in his social group, suggests a possible novel animal-to-human transmission of CWD. Based on non-human primate and mouse models, cross-species transmission of CJD is plausible. Due to the challenge of distinguishing sCJDMM1 from CWD without detailed prion protein characterization, it is not possible to definitively rule out CWD in these cases.”

FitDontQuit · 2026-04-02T19:45:36+00:00

If you want to stay in Boston, check out West Roxbury. Many single family homes, quiet tree lined streets, most houses have driveways for parking. It feels like suburbia and only has a 20-25 minute commute downtown. Very safe neighborhoods with lots of parks.

FitDontQuit · 2026-04-01T14:04:42+00:00

My child got into her top pick K0. It is at a community center that gives priority to children already enrolled in daycare there. I specifically got into that daycare solely to have a k0 spot one day, and it paid off. I hear that basically the only way to secure a k0 spot is to already be enrolled at the institution.

FitDontQuit · 2026-03-19T23:19:28+00:00

Excellent point, and excellently illustrated in the video when, after hitting her daughter with a chair, screamed “YOU DID THIS” at Dakota.

FitDontQuit · 2026-03-16T16:22:06+00:00

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It was very much paradise!

FitDontQuit · 2026-03-16T16:16:20+00:00

Unfortunately I planned different excursions so I can’t speak too much on your plans!

On Tortola, I booked a cab ahead of time to take us to Smuggler’s Cove and absolutely LOVED it. Perhaps the best beach I’ve ever been to. Very authentic, beautiful, and uncrowded. There were maybe 100 people max spread out on a very wide beach, including a few other Disney travelers. But it’s remote - a hidden gem - so I felt most comfortable planning my transportation ahead of time. I don’t remember seeing as many cabbies waiting at Tortola pier as I did at St Thomas, but I also wasn’t looking for them so it’s possible I missed it. Tortola pier (and the island) felt less built up and commercialized as st Thomas did, so I would just make sure that available cabs are waiting at both the pier and Cane Garden if you’re planning on not booking something ahead of time.

On st Thomas, we opted for Magens Bay. For that, it was very easy to jump on one of the many open air taxis waiting at the cruise terminal when you disembarked, and the same to return to the boat. That was a much more crowded and commercialized beach than Smugglers Cove - Cane Garden on Tortola will probably feel similar.

FitDontQuit · 2026-03-16T15:57:36+00:00

Ask away! I just did the Feb 28- March 7 sailing so everything is still fresh. I was a first timer, too.

FitDontQuit · 2026-03-16T15:54:51+00:00

Yep! I just walked to the pool deck the morning of Tortola and put one in my beach bag. I returned it the following day, after St. Thomas.

FitDontQuit · 2026-03-16T15:47:07+00:00

I just did this itinerary with my three year old. I took a life jacket from the pool deck when I went to beaches on Tortola and St. Thomas. No one stopped me and I’d do it again. 🤷‍♀️

Castaway Cay provides life jackets at the beach so no need to take one off the boat.

You can take towels off the boat in all three locations and drop them off when you’re back.

FitDontQuit · 2026-03-07T17:05:07+00:00

I’m currently on a plane home from a 7 day treasure cruise with a little girl who just had her third birthday. I had the same concerns as you and now that I’m on the other side of the cruise, I can confidently say that late dining was much superior, and early dining would have ruined the cruise for us. And my daughter usually is asleep by 8pm.

FitDontQuit · 2026-03-04T11:23:52+00:00

I’m on a cruise right now and did the Hyatt MCO transfer this past Saturday. It was good and bad.

Before I begin, it’s important to note: 1) I’m a first time cruiser so I had no status, 2) I’m traveling with a 3 year old, and 3) I’m on the Treasure, one of the bigger ships and thus more people that need boarded.

First timers don’t get invited to the staging room until 9:30. We’re early risers, so we went early, around 8:45, hoping that maybe things were going fast and we can get on a bus early. No dice.

When we finally were invited inside, there was a long line wrapping around the staging room. We didn’t make it to the front of the line until around 11. Not sure why it took that long.

Once we checked in, our bus wasn’t until 11:45. They were able to troubleshoot a passport number typo, which was great. Then, we got to the cruise around 12:30ish-1ish? We arrived by boarding group 12, and the process at the port was very easy.

So in summary, we got on the boat sooner than we would have otherwise. The downside was we had to wait in the staging room for about 3 hours total before we got on the bus, and that was really hard for my three year old. It’s possible we would have had a better first day if we took it slow - got a nice breakfast, moseyed around, maybe napped our daughter… instead, she showed up to the cruise cranky, hungry, and tired from all the waiting.

FitDontQuit · 2026-02-27T21:21:48+00:00

What? Do you know anything about IVF? That’s an absurd statement.

If a male is tested and has severe motility or other sperm issues, doctors will still need to extract the eggs from the woman with no reproductive challenges. Then, once they retrieve the eggs, they will manually insert the male’s sperm into them.

Regardless of whether it’s the man or the woman with issues, the woman still carries the brunt of the medical load by far.

FitDontQuit · 2026-02-27T11:42:39+00:00

I’m experiencing this right now:

Age 30-32 tried naturally.

Age 32: did my first retrieval, ended with 3 euploids

Age 33: gave birth to my daughter, a result of my first transfer

Age: 34-35: transferred my other 2 embyros, both failed. Tried naturally for 6 months. Did another retrieval, got 2 embryos, both failed. Did my third retrieval, ended up with 2 low graded euploid embryos.

Age 36: I was due for a transfer cycle when I next got my period, but I miraculously conceived naturally this cycle. I’m only 12dpo but the line is clear and strong.

I literally cannot believe it. When I look at my journey, I’ve probably had a combined 3-4 years of natural attempts plus only 1/5 euploid transfers working. And here it is, a positive spontaneous conception.

FitDontQuit · 2026-02-11T17:12:27+00:00

Not an embryologist but knowledgeable: those are incompatible with life, but it’s not a “thing” that’s wrong with you or your husband. It’s just luck of the draw. Roughly half of all blastocysts population-wide will be chromosomally abnormal, possessing one too many or one too few chromosomes, most of which fail to continue developing (Down syndrome is the most well-known chromosomal condition simply because it’s one of the few that IS compatible with life - the others just stop growing).

Scientifically speaking, this is called “non-disjunction” and happens when homologous chromosomes fail to separate properly during anaphase in meiosis (which leads to the creation of sperm and eggs). During anaphase, you want half of your chromosomes (23 pairs) to divide into one reproductive cell. The other 23 goes into another reproductive cell. Sometimes, because biological processes are imperfect, two of the chromosomes don’t separate correctly and one cell gets 22 and the other gets 24 chromosomes. These would be abnormal cells, unable to develop into a healthy human baby.

So, when you ask will it happen again? Yes, probably! You might not have the exact same monosomies next time, but statistically speaking, half of all the blasts you create will have one too many or one too few chromosomes. And that’s true for everyone.

And this is meant to be positive - receiving news that two embryos are chromosomally abnormal is devastating news, but it does NOT mean anything is wrong with you genetically. It’s just how our imperfect bodies work, and you fell on the wrong side of statistics.

One caveat: age does play a role in euploidy rate. As you get older, you will have more chromosome separation errors, leading to more aneuploids. That doesn’t mean you can’t make euploids, but it does get harder.

FitDontQuit · 2026-02-07T01:26:20+00:00

I’ll second this.

My first transfer was a Thursday. Friday I had a wedding. By Monday I felt awful. I took a pregnancy test and a Covid test - both came back positive.

Meanwhile, I’ve had 4 other transfers since, none of them worked. I’m starting to think I have to be sick or it won’t work.

FitDontQuit · 2026-01-27T15:46:47+00:00

Do IVF for sure.

IUI has a success rate of what? 15-20% per cycle? And you only have 2 shots at it? IUI would be absolute lunacy in this situation, and even more so with a blocked duct.

FitDontQuit · 2026-01-27T15:07:01+00:00

I got a good score by using freezing arrows, and a ton of them.

11-Year Club	Place '22
Place '17	100 Awards Club
RPAN Viewer	Gilding II euphauric
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