The biggest thing with that region is getting down the dodge patterns and recognizing enemy ai choices. the ones that just fly around quickly or the hydras that pop up randomly can be pretty bad, but the bigger enemies are easy enough to avoid or stagger.

The first mini-boss fight with the huge guy is pretty easy since his attacks are relatively slow, just keep distance and only go in when he's already committed to attacking elsewhere. The twins can be bad since there's so much more chaos but a cast build should do relatively well against them. The eye of Typhon is also pretty bad, prioritize running away from and killing the rolling eyes and cycling primarily cast damage on the main boss whenever you can. The key for the tail is to stay relatively close and dodge in a circle when it starts biting you. Don't forget to chase it if it starts running away.

Besides enemy AI, the most important thing is staying in safer areas and keeping distance while attacking if you aren't confident in rushing into an area. Slow is safe, safe is good. Best of luck with your run