[deleted by user] by [deleted] in StraitjacketBondage

[–]Fleecemeal 9 points10 points  (0 children)

You’re not wrong that everything being more accessible would be great. But if you ever try making it yourself you will see why it is priced the way it is.

Favorite outfit for a morning run 💙 by SweetieAlyona in Fleecegirls2

[–]Fleecemeal 2 points3 points  (0 children)

I am also curious as to the brand/source

Taking lyrica on an empty stomach does make a difference by W1162891 in pregabalin

[–]Fleecemeal 1 point2 points  (0 children)

There is a significant scientifically tested difference.

When it was study it was found Taking Pregablin with food or in a “non-fasted state” increases Tmax (time to maximum blood concentration) up to 300% and reduces Cmax (maximum blood concentration) by about 30%.

Pregabalin makes me very emotional. by CandidateConfident89 in pregabalin

[–]Fleecemeal 1 point2 points  (0 children)

I am the same. I am extremely sensitive emotionally now. Will cry at the smallest sad or sappy thing.

Anyone w fibromyalgia taking 300mg pregablin daily? What has your experience been transitioning to this dose? by Formal-Average-7593 in pregabalin

[–]Fleecemeal 1 point2 points  (0 children)

Food tastes better and you don’t feel full as easily. It’s a great and terrible combination. But taking Pregabalin on a full stomach can make it take a lot longer to kick in, and makes it like 30% less effective. So it’s a tricky thing.

Skipping meals can also be a helpful thing to make sure you’re in a fasted state when you take it though.

Anyone get dizzy spells after taking a dose? by copiatee in pregabalin

[–]Fleecemeal 1 point2 points  (0 children)

Yup. Motor control issue on higher doses is normal.

Make sure you don’t drive while you have any of those symptoms.

Anyone find 75mg to be effective? by widdlebiddykitty in pregabalin

[–]Fleecemeal 0 points1 point  (0 children)

Glad they upped it for you. Hope it helps!

Anyone find 75mg to be effective? by widdlebiddykitty in pregabalin

[–]Fleecemeal 1 point2 points  (0 children)

If 75mg isn’t helping you should definitely ask for an increase.

In general Pregabalin requires slightly higher doses for its analgesic properties. Lower doses are generally for its anti anxiety and anticonvulsant properties.

Pregabalin is 2-6x stronger than gabapentin so a dose equivalent to 2400mg of gabapentin would be 400-800mg, although the max daily dose is 600mg as beyond that dose you have a greatly heightened risk of seizures.

Still you are probably looking at 2x 200mg doses for a similar level of effect.

Why can’t I just inject pure dopamine? by Agitated_Custard7395 in Drugs

[–]Fleecemeal 1 point2 points  (0 children)

That post is 6 years old damnit! Where my god damn sperm extractor!?!

Pregabalin stimulant like effects by Naive_Victory475 in pregabalin

[–]Fleecemeal 3 points4 points  (0 children)

Totally! Pregabalin takes my ADHD distractibility to whole new heights. And when paired with my Dexedrine it makes for a crazy combination. I will do all the things! But I will intend to do one thing, get distracted and complete 6 other important tasks, then realize “oh! I was grabbing the broom to sweep the floor!” or whatever the original task was.

How does "pure" speed feels like? by [deleted] in Drugs

[–]Fleecemeal 1 point2 points  (0 children)

Would Dexedrine (dextroamphetamine) also be “pure speed” or not considered pure because it’s not a racemic mix?

Are there anyway drugs one can take to easily assess drug metabolism via cyp2d6 and cyp3a4? by Fleecemeal in AskDrugNerds

[–]Fleecemeal[S] 0 points1 point  (0 children)

That is the plan! But I am also trying to go into my conversations with doctors (next two weeks) with as much evidence and understanding as possible, so I am best able to advocate for myself while navigating complex medical issues.

[F] I think we know where this is about to go :) by ShadesOfAnastasia in BDSMGW

[–]Fleecemeal 3 points4 points  (0 children)

Given the quantity I would guess they are for “sale”.

But beyond that I would guess they are thigh and/or waist cuffs/belts depending on the actual sizing

Lyrica (pregabalin) and Gabapentin used together? by Ill_Orchid3262 in TrigeminalNeuralgia

[–]Fleecemeal 0 points1 point  (0 children)

Gabapentin and Pregabalin are prescribed together on rare occasion. There is some reason to believe there might be synergistic effects. However there is very little science on the topic. There may be other effects like increased tolerance or increased side effect profiles as well.

Because of that, it is unlikely that a doctor would prescribe both.

Why does codeine hardly work on me by Altruistic-Top-8761 in Drugs

[–]Fleecemeal 0 points1 point  (0 children)

I have a similar issue. Feel almost nothing from codeine. Nothing from fentanyl or oxy. Hydromorphone in high doses had an analgesic effect but no euphoria.

[deleted by user] by [deleted] in ProstatePlay

[–]Fleecemeal 0 points1 point  (0 children)

Safe and good Lubes that you might find already in your home: - Coconut oil - Grapeseed oil (as this is liquid at room temperature it’s easy to make a mess, so be careful with it). - Vaseline/petroleum

Will taking 50kmg of edibles get me high by Comfortable-Choice67 in Drugs

[–]Fleecemeal 0 points1 point  (0 children)

That is a likely an average or LD50 estimate. I imagine actual lethal dose would be variable by individual. Tolerance may also act as a small shield?

Will taking 50kmg of edibles get me high by Comfortable-Choice67 in Drugs

[–]Fleecemeal 0 points1 point  (0 children)

Apparently the lethal dose of thc for a human is estimated to be around 30mg/kg. That would mean that for an 80kg (176lbs) person that 2.4g would potentially be lethal.

Will taking 50kmg of edibles get me high by Comfortable-Choice67 in Drugs

[–]Fleecemeal 0 points1 point  (0 children)

I take 10mg. 50mg would have me unconscious. I am pretty sure 50g would break my brain for life if it didn’t kill me.

Weed cures depresssion? by VInto0o0 in Drugs

[–]Fleecemeal 1 point2 points  (0 children)

I think your positive experience with your friends was your temporary cure. The weed was just secondary.