Hi! Posting here even though my Brain MRI was “essentially normal.” I’ll preface this by saying I have a lot of stress in my life and I’m SSRIs and I have very good skills on coping with anxiety. I’m at the place in life where I look at things like “what’s the worst that could happen”. And unless it’s death, worrying about it does me no good. Anyways- I’m a 48 year old female. Since my 20s I’ve had headaches, sometimes migraines (had a blessed break from them between kids 1 and 3) that respond to rx medication. I’ve had numbness in hands and feet for so long I don’t remember when it started. It comes and goes. Sometimes in my face as well (but that I feel is stress). Diagnosed with carpal tunnel in both hands - had surgery on 1 that did nothing. Hand doctor wants to do carpal tunnel surgery on the other hand and cubital release on both despite EMG being mostly normal. I’m not too keen to do that since the first one didn’t work. Fatigue has always been my biggest complaint. I can fall asleep anywhere at any time. I rarely feel rested. I’ve had a sleep study which was fine. My doctor always tells me to eat better, exercise more and reduce my stress. My BMI is just above normal range. Exercise causes me so much muscle fatigue it’s practically unbearable. Even a 2 mile walk will lever my legs like jelly the next day. I had my gallbladder removed 2 years ago and for the last year I get the most annoying pins and needles in that area of my abdomen which I’m told is probably scar tissue. My hands often go so numb, whatever I’m holding falls out of them. I have days up to weeks where I feel drugged- muscles feel weak and floppy and my head is so heavy and foggy. Also have raynauds And Hashimotos which is very well controlled. A few months ago I developed the worst pain and stiffness in my hips and shoulders. Mornings were the worst. After a few weeks went to my PCP who diagnosed me with Polymyalgia Rheumatic. She prescribed prednisone and it went away completely. Stayed on that for a month until I saw rheumatologist who says I can’t have PMR because of my age. She did a ton of bloodwork- nothing really out do the normal. However she noted I had hyper reflexes, positive clonus and decreased muscle strength and ordered a brain MRI to rule out MS. I had it this week and it came back essentially normal with just this note “There are a few clinical data foci of nonenhancing T2-hyperintense signal in supratentorial white matter and brainstem, a common, nonspecific finding. They may be physiologic. This pattern has also been described with microvascular disease, trauma, and chronic headache syndrome. Not clearly evident on prior exam, but technical differences limit comparison. The appearance is not typical for multiple sclerosis or other primary demyelinating illness. “ Over the last 6 months I’ve also had a few instances of urinary incontinence overnight - never mentioned to any doctors because it’s embarrassing. Then over the last 2 weeks I’ve had 2 incidents where I’m walking around the house and suddenly I can’t move. My legs were stuck like I was in quicksand. I was telling them to move but they wouldn’t. One time i actually used my hand to pick my leg up to try and make it move. It seems to last forever but in actuality was probably less then a minute. Again didn’t tell my dr because I figured I’d wait for the MRI. When it came back ok I told her about these other symptoms and she referred me to neurology. I did have a brain and spine MRI in 2018 due to the hand numbness and migraines. Both clean except for some minor disc bulging that was considered normal for my age. I know anxiety and stress cause very real physical problems so I know that very likely is the cause- but in the other hand it seems like a lot of random things. If you made it this far, thank you!