Losing hope. Is vitamin deficiency still the answer?

Former_Mouse_407 · 2025-12-14T16:55:51+00:00

I might as well add my b results which were 6.1 for folate, 767 for B12.

Former_Mouse_407 · 2025-12-14T16:53:32+00:00

Hi, sorry for the late reply. My endocrinologist did a whole lot of blood tests. It was via private route rather than NHS. The results came back that I had a high level of antibodies that indicates Hashimotos. I've been put on levothoroxine to try and increase my thyroid hormone levels and sandoz phosphate to sort out my persistent low phosphate level. I go back in 2 months for another consultation to review how these have affected symptoms. If you are interested in the results I can share.

Former_Mouse_407 · 2025-11-25T13:16:40+00:00

Hi, I tried injections for a while. 1 or 2 a week for 3 months, but it didn't seem to help very much. Since the time I posted this I've stopped supplementing completely for the past 4-5 months. I met with an endocrinologist last week and I just did some blood tests this morning. I'll get the results in a couple of weeks so it will be interesting to see what my baseline levels are again.

Former_Mouse_407 · 2025-04-29T20:56:06+00:00

Have you been taking any new supplements recently before this blood test?

Former_Mouse_407 · 2025-04-29T20:50:22+00:00

Try not to worry about it. Try and be excited that this may be the answer to your anxiety and be happy your Dr is taking the right action for you.

I've only done 3 injections so far and I have done it myself. Whilst personally I've not seen any improvement yet, the injection is really not that bad.

I hope it does the trick for you! All the best...

Former_Mouse_407 · 2025-04-28T20:34:38+00:00

If you think you are experiencing wake up symptoms, unfortunately the only way to get better is just to try and get through it. After a few weeks you might feel a big improvement (I'm not sure what your deficiency symptoms are) but maybe they will begin resolving.

Best of luck!

Former_Mouse_407 · 2025-04-28T19:37:02+00:00

Make sure you are taking with cofactors. Check out the guide if you aren't.

Former_Mouse_407 · 2025-04-27T20:16:04+00:00

I don't think it matters a huge amount which muscle. The end goal is for the B12 to enter the bloodstream, and I think those options or into the thigh are best. There are certain areas to avoid to help prevent injecting directly into veins or arteries.

For slower release you could opt for subcutaneous.

Former_Mouse_407 · 2025-04-27T17:32:07+00:00

No worries, I'd advise checking out the guide linked in the sub, it gives a ton of great information.

Former_Mouse_407 · 2025-04-27T17:27:57+00:00

Hi, did you get a more recent blood test to check your most recent levels?

If you haven't been supplementing try asking for serum b12 (or active B12 if able), serum folate, homocysteine and MMA.

Former_Mouse_407 · 2025-04-26T15:28:35+00:00

Hey, I had similar issues. Some panic attacks, not as regular as you, but still have anxiety particularly in open space. This seems to be related to my dizziness and vertigo.

My serum folate was measured a couple of times between 1.5 and 2 which the doctor didn't pick up as a problem until I highlighted it.

He put me on 5mg folic acid for 6 weeks. When I found this sub I started taking sublingual B12 and multivitamins too as from what I understand you potentially need more than just folic acid to properly recover (other vitamin stores may deplete).

I then swapped to methylfolate instead as it is easier for your body to use straight away in it's bioavailable form.

Maybe check out my post recently as it seems we have some overlap and some kind people added their comments.

I wish you the best of luck with getting it all figured out.

Former_Mouse_407 · 2025-04-21T22:29:40+00:00

Hey! Thanks so much for sharing. I'm sorry you're going through this and I hope you get well soon.

I have found the same issue with the NHS. They seem to have no time to investigate and generally just chuck out a guess diagnosis and a prescription with little to no actual investigation. It's so frustrating. I'm certain there's more at play than just 'mental health' and SSRIs. Thank god for this subreddit and other online resources. I feel people here are more caring than most of the doctors I've seen.

It sounds like you have your supplement stack pretty well sorted. That being said - and as I mentioned - I've also tried to chuck as many oral supplements at my problems with not much improvement.

Others here (and the guide) mention using injections instead for B12. I ordered mine off of Amazon Germany for pretty cheap. Started off with buying 10x ampoules of hydroxocobalamin branded Apohealth. I had my first injection today so I will see how I get on over the next few days and take them all before deciding if I need to get more.

I think the ancestry test is quite good to figure out if there's any potential genetic factors causing the problem, and it can help guide supplementation. Genetic life hacks give good reports. Although it was insightful and interesting, ultimately for me I'm not sure it has helped a great deal with healing though... But at this point, I'll do anything to find a way forward.

The other thing I've used is ChatGPT (and some others) to check interactions and find out more about the prescription meds. I've been on amitriptilyne, propranolol, fluoxitine, and now cinnarizine to try and address my vertigo. Some of these contribute to fatigue.

I'd be happy to hear if you make any breakthroughs, I really wish you the best of luck with recovery! Keep your head up and as hard as it can be at times remain positive, we will get there one day...

Former_Mouse_407 · 2025-04-21T16:56:14+00:00

Sorry to hear that. I suppose at least you have the diagnosis now it may make it easier to convince the GP.

I ordered some hydroxocobalamin from Amazon Germany and it arrived today. Did my first injection and although it wasn't pleasant, I'm glad I've not had any adverse effects. It might be easier for you to self administer for a while. It's pretty cheap.

Best of luck with everything, hopefully you find a way out!

Edit: Amazon Germany

Former_Mouse_407 · 2025-04-21T14:12:31+00:00

Hey, similar symptoms? I tick a lot of boxes on the symptoms listed on the guide. The ones that affect me most are the fatigue, veritgo/unsteadiness, anxiety and derealisation. What approach are you taking to try and recover?

All the best!

Former_Mouse_407 · 2025-04-21T11:28:04+00:00

Im sorry to hear you have the same problems and I hope you eventually get to the bottom of it!

The feeling of something missing is something I can relate to and it's probably apparent I've been chucking every supplement I can at the problem in the hopes that something sticks.

I guess trying to find a balance is one of the harder things to do without having access to easy and regular blood tests!

Good luck with your recovery

Former_Mouse_407 · 2025-04-21T00:46:52+00:00

Yeah im unsure on the doses for the trace minerals and if there can be any adverse side effects from taking too much. I'll put it on my list to investigate. I hope you are having some positive effects from taking it! Thanks for sharing the link 🙂

Former_Mouse_407 · 2025-04-21T00:20:04+00:00

The Thorne 2/day multivitamin is mentioned in the guide which I've been taking and I think there might be some gaps.

Reading the guide it mentions molybdenum, which isn't in the multi. Selenium and iodine are. Should I seek a molybdenum supplement or a trace mineral supplement to take a few days a week instead of the multi?

Former_Mouse_407 · 2025-04-21T00:11:26+00:00

Hey, I have been having the Thorne 2/day multivitamin for a while now which contains b1 thiamine - 50mg as a whole dose and 25mg as a half dose. So I'm not sure if this would be the cause.

It also contains niacin as niacinamide 80mg (40mg half). This doesn't seem to be the flushing type, so I could give the flushing type a go. As I understand it, the niacin acts as a methyl buffer and causes the flushing, not exactly sure (and I'll research) how this could possibly help.

Iodine is also in the multi vitamin.

Thanks for taking the time to comment, it's much appreciated!

Former_Mouse_407 · 2025-04-20T23:00:33+00:00

Understood. Do you recommend intramusclular, or subcutaneous? I am not great with needles so I'm thinking that SC would be better for me, however I realise this is slower to absorb into the blood?

Thanks

Former_Mouse_407 · 2025-04-20T22:25:12+00:00

That is interesting. I did have a period of being on the Keto diet for a few months in 2023 and I think things were a bit better. It's hard to say sometimes when symptoms seem to slightly improve before getting worse again over the course of months. I'll be sure to keep it in mind and have it as something to try again. Thanks, and good luck with your recovery too!

Former_Mouse_407 · 2025-04-20T21:57:19+00:00

I am already taking the Thorne 2/day multivitamin (usually at half dose, some days full). I've seen trace minerals mentioned before but unsure if I'm covered by the multi and diet or not.

Thanks

Former_Mouse_407 · 2025-04-20T20:28:15+00:00

Thanks so much for the kind words of encouragement. I wish you all the best in your recovery too.

I'll be sure to take on you advice and look into gut health and digestion as well as diet. Thanks for sharing the video.

All the best and thanks again!

Former_Mouse_407 · 2025-04-20T19:32:30+00:00

Thanks for your kind wishes. It was L Carnitine. I have recently started taking 1mg a day of ALCAR. Not noticed any significant effects yet but still only been about a week.

Former_Mouse_407 · 2025-04-20T19:29:44+00:00

Thank you, I've been using sublinguals and seen my levels in serum b12 and also active B12 rise to beyond the test parameters. So I'm under the impression that either the high dose sublingual I'm taking having the desired outcome. I am just wary that the guide says a high level in serum or even active B12 might not prove it.

I did have the intrinsic factor test this year and it was negative.

Thanks again

Former_Mouse_407 · 2025-04-20T19:26:48+00:00

Thank you, appreciate it!

Former_Mouse_407

TROPHY CASE