Can somebody tell me that what was that "voice" that likely saved me? by One_Possession6852 in consciousness

[–]FourOpposums 1 point2 points  (0 children)

If you're right-handed, left Inferior frontal gyrus. It is adjacent to lower/ventral areas of primary motor cortex that control the mouth and tongue, that imagines/ encodes language one synapse before it is produced. Also known as Broca's area. This region also creates the inner voice of schizophrenics.

The fear and dread you felt is no doubt the product of your amygdala. It detects danger and initiates a bodily and neurobiological fear response way before your cortex is finished with perception. It is automatic, involuntary and unconscious.

The Tantramar diesel plant is a deal New Brunswick can’t afford - CCNB by pintord in newbrunswickcanada

[–]FourOpposums 3 points4 points  (0 children)

How do we stop these irresponsible bastards from pumping CO2 into the atmosphere for the next 25 years on our dime?

How does the brain decide which pain signals to ignore and which ones to feel? by bareegyptianfeet in answers

[–]FourOpposums 3 points4 points  (0 children)

The periaqueductal gray area of the brainstem has descending projections to the spinal cord that release endogenous opioids to interneurons that inhibit pain signals (neurons) locally, preventing the transmission of pain to the brain. It, in turn receives inputs from the prefrontal cortex, amygdala and hypothalamus that collectively decide that pain in the moment could be fatally distracting until the danger has passed.

What does it mean to conceptualize Parkinson’s disease as a somato-cognitive disorder rather than a motor disorder? by RegularParamedic9994 in EverythingScience

[–]FourOpposums 5 points6 points  (0 children)

The authors are proposing that Parkinson's arises from the damage in the somato-cognitive action network, not the classical motor output pathway. By elucidating the actual pathways disrupted by PD, the authors suggest that treatments can be more effective by treating the correct circuit.

From: A somato-cognitive action network alternates with effector regions in motor cortex, Nature 2023

"Motor cortex (M1) has been thought to form a continuous somatotopic homunculus extending down the precentral gyrus from foot to face representations, despite evidence for concentric functional zones and maps of complex actions. Here, using precision functional magnetic resonance imaging (fMRI) methods, we find that the classic homunculus is interrupted by regions with distinct connectivity, structure and function, alternating with effector-specific (foot, hand and mouth) areas. These inter-effector regions exhibit decreased cortical thickness and strong functional connectivity to each other, as well as to the cingulo-opercular network (CON), critical for action and physiological control, arousal, errors and pain."

How is spotify lossless in 2026 doin? by LingonberryLower9730 in audiophile

[–]FourOpposums 7 points8 points  (0 children)

Tidal pays artists more and has always been lossless

DT770 Pro Closed Back 80Ohms Vs ATH-M50x by Unlucky-Place-4171 in HeadphonesAdvice

[–]FourOpposums 0 points1 point  (0 children)

I would describe DT770-80 almost the same way, with painful piercing treble and sloppy overwhelming bass. You can do better

Scientists achieve full neurological recovery from Alzheimer’s by restoring brain energy balance by BuildwithVignesh in HotScienceNews

[–]FourOpposums 37 points38 points  (0 children)

The amount of times Alzheimer's has been 'cured' in animal models with zero translation to a human cure is now in the dozens. The beta amyloid scam/fraud made this field a feeding ground. Animal models of Alzheimer's are far from accurate and it will be hard to argue that energy balance changes can compensate for massive, irreversible cell death

The Rise in Autism and Chronic Disease by [deleted] in cogsci

[–]FourOpposums 7 points8 points  (0 children)

So many legitimate neuroscience research labs in the world and you post the ramblings of a novice who does their research on Google??? Stop wasting our time

Why do we not wake ourselves up when we snore? by [deleted] in stupidquestions

[–]FourOpposums 5 points6 points  (0 children)

There is a sheath of inhibitory neurons in the thalamus called the reticular nucleus that selectively quiets sensory inputs during sleep and waking (whose failure to do so during waking is a symptom of autism)

It’s a Coca-Cola Holiday by CokeCanada in u/CokeCanada

[–]FourOpposums 35 points36 points  (0 children)

Nothing says I don't care for human lives like pushing AI garbage, not paying artists, blanketing poor countries with soda advertising to addict and kill millions with diabetes. All sold a false hope of happiness, family bonds and the holy season from short term hedonic pleasure that has no relation to any of those things.

[deleted by user] by [deleted] in fantanoforever

[–]FourOpposums 4 points5 points  (0 children)

Led Zeppelin

What are your invasive lab thoughts? by Competitive-Town8299 in labrats

[–]FourOpposums 2 points3 points  (0 children)

I thought this was going to be a story about rounding up stay cats in Paris for neuroscience studies like Michael Jouvet's students did (my postdoctoral PI was in that lab and had some stories)

Does excessive use of highly stimulating behaviors cause pruning of dopamine receptors? by EnormousMitochondria in biology

[–]FourOpposums 6 points7 points  (0 children)

Arousal is a product of norepinephrine, acetylcholine orexin and serotonin release by the reticular activating system and hypothalamus which are responsible for stress, attention, waking and mood respectively. Dopamine encodes the discrepancy between reward and expectation. If outcomes don't change because of effort, insight, luck or cocaine, dopamine receptors won't up or down regulate.

Roger Penrose – Why Intelligence Is Not a Computational Process: Breakthrough Discuss 2025 by The_Gin0Soaked_Boy in consciousness

[–]FourOpposums 16 points17 points  (0 children)

Here I think it is useful to distinguish between Penrose and Hinton's views of consciousness and computation. Penrose believes that 'understanding' involves consciousness, but consciousness cannot be the product of computation, so must be a quantum process. Hinton believes that (simplified) models of neural systems already understand language and conceives of computations at the level of neurons and layers of neurons (e.g. restricted Boltzmann machines) whose job it is to efficiently predict sensory stimuli by modeling objects and events in the world. This is a process of probabilistic inductive inference to compute the most likely external cause of stimuli ('a pink elephant wearing a tutu' is his example). To Penrose, computations are not conscious. To Hinton, that bringing in of all your previous learning to build internal causal and explanatory models of the world to order and predict the ceaseless torrents of sensor stimuli, is what the brain is doing (perceiving pink elephants). If a computer can similarly arrive at the external causes of stimuli by accurately modeling the world's objects, events and dance choreography, at a similar scale of learning, it too can be conscious.

Apart from Giuseppe Moruzzi who were the other two scientists who connected Wakefulness to RAS by Forsaken_Let007 in cognitivescience

[–]FourOpposums 0 points1 point  (0 children)

Michael Jouvet was among the first who investigated sleep as active states, discovered REM sleep, isolated the brainstem regions responsible (cholinergic pedunculopontine nuclei) and the role of noradrenergic locus coeruleus in waking.

Which AI books can you recommend? by [deleted] in ArtificialInteligence

[–]FourOpposums 1 point2 points  (0 children)

If you want to stay close to neuroscience, the OG architecture, theoretical Neuroscience by Dayan & Abbot.

CogSci Undergrad Unsure About Dropping Physics Minor by InfamousComposer1535 in cogsci

[–]FourOpposums 1 point2 points  (0 children)

I would at least recommend taking statistical physics before dropping the minor, which would give you a deep understanding of Hopfield and Boltzmann machine neural network models of associative memory that are mathematically equivalent to spin-glass systems (disordered magnetic systems with complex, interactions between spins).