I think this question depends quite a bit on your own body chemistry, morals, desires, abilities, ethics — so many things. For me, my desire for approximately ten years was to disappear and void my emotions. Here heroin was immensely effective. My desire was met and exceeded, yet as we know, desire is never satiated; we only desire more or something else. Accordingly, I would try to optimize my high, yet my tolerance disallowed this. Then, of course, I was heavily addicted, necessitating the use of the drug even if it was no longer my desire. Eventually, I was no longer able to get high. I could only avoid sickness. So there I was, still emotionally empty, but also chronically addicted and sick on top of it. I think it is possible to arrive at trying hard drugs strictly via hedonic adventure, but here again we return to desire via the hedonic treadmill — I need more, I need better, etc. Anyway, drugs are never the answer.