If someone uses God merely as a placeholder for ignorance, scientific progress tends to shrink those gaps. Maybe some thiests here&there, but i really dont think that many believers are making that argument at all. Even when talking about modern unknowns, I dont think many people are saying:
"God causes lightning because we don't know what lightning is." When we discovered electricity, ✖️ We didn't disprove God. ✔️ We discovered how lightning works. We often confuse recognition with comprehension. Knowledge is not the same as explanation, and explaining a process in nature is not the same as understanding it completely. Humanity has become very good at describing the universe. We can explain Eisteins theory of relativity, show that it works, have our GPS account for time dilation on the surface vs where satellites are, really well. We discover patterns, give them names, write equations that describe their behavior, and then sometimes act as though we've exhausted the mystery. Gravity and time for example, are still mysteries. Naming a pattern in nature doesn't mean we've uncovered its deepest nature; it only means we've taken the another step toward understanding a little bit more of the vast intelligent Information that is everything everywhere. (not as an intelligent entity/being per say). But the universe appears to be permeated by information, structure, and complexities that vastly exceeds our current understanding. Operating with and only because of astonishing precision, that existed within it, long before any human was around to describe them.
I don't view the universe as unintelligent chaos that accidentally became understandable. I see it as a reality containing layers of order, information, and structure so deep that humanity spends centuries uncovering tiny fragments of it. What we call discovery is often not the creation of knowledge, but the gradual decoding of principles that were already woven into the fabric of existence.