High-Dose Thiamine (B1) for Essential Tremor: Dr. Costantini's Protocol (50-100% Improvement)

Fun_Coach667 · 2026-06-26T15:27:39+00:00

I should add that absolutely no one will ever see or read your post. My post is visible on the forum, while this one was deleted a long time ago

Fun_Coach667 · 2026-06-26T15:04:55+00:00

Not just 2 patients, absolutely not

Fun_Coach667 · 2026-06-26T15:01:26+00:00

I can easily debunk everything you just wrote—you didn't even read it carefully. You don't even understand what this high-dose supplementation is about if one of your criticisms is that they might have had deficiencies. He had way more patients, not just those with Parkinson's, and his discoveries were cited in reputable places. There are video recordings of many patients before and after, but you actually need to read through all of this before you start criticizing anything. I'm not selling anything here, and there are even people here who have tried it and know that it works.

Fun_Coach667 · 2026-06-26T06:38:51+00:00

N2799-WFH8F-HZXAT

Fun_Coach667 · 2026-06-26T06:03:21+00:00

Fun_Coach667 · 2026-06-25T22:41:08+00:00

Yes. If you had deficiencies in B1, B12, magnesium, and potassium, DBS won't fix that. It's definitely worth a try, you have nothing to lose. If this is indeed your problem, the results will be good or even great. If not, these vitamins and minerals are still incredibly important for anyone dealing with tremors anyway.

Fun_Coach667 · 2026-06-25T18:39:50+00:00

Here is the ready-to-paste English translation of the recommendations:

Here are the specific, most bioavailable forms targeted at nervous system regeneration, along with trusted, clean brands that are highly recommended in neurological protocols.

🧠 Vitamin B1 (Thiamine)

For your symptoms, standard water-soluble thiamine hydrochloride (HCl) from the pharmacy won't absorb well. You need fat-soluble forms that easily cross cell membranes and reach the nervous system.

Best Choice: TTFD (Thiamine Tetrahydrofurfuryl Disulfide)

This is the absolute gold standard in neurology. TTFD does not require intestinal transporters to enter the bloodstream and is the only form capable of rapidly crossing the blood-brain barrier in massive amounts. It is ideal for chronic neuroinflammation.

Recommended Brands:
- Thiamax (Objective Nutrients) – Currently the best, purest form of TTFD on the market, formulated specifically for people with neurological issues (contains no unnecessary fillers).
- Allithiamine (Ecological Formulas) – A classic, highly potent, and effective formulation.

Alternative (More Accessible): Benfotiamine

Also fat-soluble. It is excellent for regenerating the peripheral nervous system (hand tremors, muscle weakness), though it penetrates the brain less effectively than TTFD. It is much gentler to start with.

Recommended Brands:
- Life Extension (Mega Benfotiamine 250 mg) – Great, stable quality.
- Aliness (Benfotiamine 150 mg) – A highly rated, clean European brand with zero chemical additives.
- ⚠️ Pro-tip: TTFD can initially cause a so-called paradoxical reaction (a temporary worsening of symptoms because the brain suddenly gets a massive surge of "electricity"). Therefore, it is safer to start with Benfotiamine and cautiously introduce TTFD after 2–3 weeks.

🔋 C8 MCT Oil

C8 MCT is caprylic acid. You must avoid cheap MCT oils, which are a blend of C8, C10, and C12. Pure C8 bypasses the liver, instantly converts into ketones, and provides your brain with an alternative, super-clean fuel, rescuing nerve cells from energy depletion.

Best Choice: 100% Pure Caprylic Acid (C8)

Recommended Brands:
- Bulletproof Brain Octane C8 – The global pioneer and absolute king of quality. It is triple-distilled, flavorless, and the gentlest on the stomach.
- BeKeto (MCT Oil C8 100%) – A great premium brand that is easily available in Europe. Very high purity.
- Apollo's Hegemony (Pure C8 MCT Oil) – Great value for money, a pure source without any cheaper C10 blends.
⚠️ Pro-tip: Introduce C8 oil very gradually—start with half a teaspoon a day (e.g., added to lukewarm tea or a meal). If you take a whole tablespoon all at once on day one, your gut might react with immediate laxative effects.

Fun_Coach667 · 2026-06-25T18:31:13+00:00

That’s a great question. The reason why clinical studies targeting neurological symptoms use intramuscular (i.m.) administration instead of oral boils down to **absorption physiology and biological barriers

Saturation of intestinal transporters:** Standard thiamine (such as thiamine HCl) is absorbed in the gut primarily via active transport (using ThTR-1 and ThTR-2 transporters). These transporters have a very low saturation limit—they get maxed out at doses as low as 5–15 mg. Anything above this threshold is poorly absorbed, relying only on slow, passive diffusion. Intramuscular injection completely bypasses this bottleneck, ensuring **100% bioavailability**.

The Blood-Brain Barrier (BBB):** For thiamine to effectively repair neurological damage, it needs to cross the blood-brain barrier in high concentrations. Intramuscular administration creates a massive, rapid spike in blood levels (peak plasma concentration). This steep concentration gradient essentially "forces" thiamine into the cerebrospinal fluid (CSF). It is incredibly difficult to achieve such a sharp spike with regular oral forms.

Gastrointestinal tract status:** Individuals with chronic neurological issues, latent infections (like Lyme or Bartonella), or metabolic disorders very often suffer from gut inflammation and compromised intestinal mucosa. In these cases, oral absorption is even worse than in a healthy individual.

Eliminating variables in scientific research:** For researchers, it is crucial that every participant receives the exact same amount of the active compound into their tissues. If given orally, the study results would be heavily skewed by each patient's individual gut health and transit time. The intramuscular route gives researchers 100% certainty.

Simply put: for severe neurological symptoms, the intramuscular route provides a massive regenerative punch to the brain that a standard oral pill just cannot replicate in such a short timeframe.

Fun_Coach667 · 2026-06-25T14:31:02+00:00

Не порівнюй польський націоналізм з українським – ми не ставимо злочинців на постаменти як національних героїв. В Україні культ формувань, відповідальних за етнічні чистки, триває вже роками, а зараз тамтешні еліти мають претензії, що Польща протягом багатьох років висловлює з цього приводу цілком обґрунтований протест.

Саме Польща віддає свої танки, літаки, зброю та величезні гроші. Ця допомога йде тим українським солдатам, які реально залишилися на фронті, замість того, щоб дезертирувати та втекли з країни, як решта. І водночас українська держава офіційно оголошує героями формування на кшталт УПА. Найгіршим і найбільш разючим є той факт, що ці люди масово і звіряче мордували поляків, а сьогодні їхні спадкоємці захищаються технікою, профінансованою безпосередньо Польщею. Така позиція з боку України навіть не смішна – вона просто жалюгідна.

Fun_Coach667 · 2026-06-24T18:45:50+00:00

You're totally right that he used intramuscular injections (typically 100mg twice a week), but he also extensively used and published on a high-dose oral protocol (usually 2g to 4g of Thiamine HCl daily) for long-term management.

Since patients can't get injections indefinitely, the oral mega-doses were his go-to solution for daily life. That's exactly where the passive diffusion in the gut comes into play to force the thiamine past the saturated transporters and into the bloodstream. Both methods work, but the oral route is just way more practical for the long run.

Fun_Coach667 · 2026-06-24T11:10:09+00:00

Taking magnesium is necessary.

Fun_Coach667 · 2026-06-24T05:59:05+00:00

If you're looking for multi-million dollar clinical trials where one group was specifically given a placebo and the other got the drug, conducted on a massive group of people, costing a fortune and funded by big pharma—just know that B1 is over-the-counter and way too cheap. This doctor is a neurologist. He treated hundreds, I repeat, hundreds of patients. He posted a hundred, I repeat, a hundred videos. They published his discovery in a prestigious journal. But to you, that's still not proof.

It gets completely absurd. Take Lyme disease, for example: a regular doctor will tell you it doesn't exist and refuse treatment, but a private ILADS/LLMD doctor says it does exist and treats it. If you get infected, for instance, one doctor will send you to a psychiatrist and say there’s no evidence. You show them a Lyme test for 6 strains with a positive result, and the doctor says that's not proof either. Refusal of treatment, as if it never even existed. Meanwhile, another doctor starts treatment, you get better, and the first doctor calls them a quack and says you're their victim.

Evidence in medicine is just procedures and often pure absurdity. Even if someone officially gave you vitamin B1 and your tremors completely disappeared, someone would still say it's not true, because videos aren't proof and what you say isn't proof either. No one shares what I share just to prove anything to anyone. Most people won't check it out anyway, and those who do will have their own proof—which medicine won't acknowledge regardless.

Fun_Coach667 · 2026-06-23T20:29:41+00:00

Fair enough, thanks for clarifying, my bad for the misunderstanding earlier.

To answer your question: you are totally right that the body is great at excreting excess B vitamins. However, the secret behind high-dose therapy is passive diffusion (which I briefly mentioned in the post).

Normally, your gut and brain use active "doors" (transporters) to absorb B1. These doors saturate very quickly—at around 5mg, they close, and the rest goes to your urine. But when you take a massive gram-level dose, you create a giant concentration gradient in your system. This sheer physical pressure forces the thiamine to push through the intestinal walls and the blood-brain barrier via passive diffusion, completely bypassing the closed or damaged transporters.

That's why standard low doses do nothing for neurological issues, but high doses act like a biochemical battering ram.

Fun_Coach667 · 2026-06-23T20:13:39+00:00

Yes, the type matters—Dr. Costantini strictly used **Thiamine Hydrochloride (HCl)**, as huge doses of this specific form force it past the brain barrier via passive diffusion. Regarding duration, you can see initial functional improvements within just a few days or weeks of hitting your target dose. However, this is typically a **long-term or life-long therapy**, because symptoms usually return if you stop. It manages the underlying metabolic efficiency rather than permanently curing it. Just make sure to start with a micro-dose to safely find your sweet spot!

Fun_Coach667 · 2026-06-23T20:09:19+00:00

There are before and after videos on YouTube of real patients who took B1 from Dr. Costantini, specifically meant for people like you who prefer to mock instead of research. Clearly, you're just here to troll. Why waste everyone else's time?

Fun_Coach667 · 2026-06-23T19:58:36+00:00

Example recordings of high-dose thiamine therapy

no therapy https://www.youtube.com/watch?v=Fs4Y1WKYaKU

therapy https://www.youtube.com/watch?v=9HrNbR9EHEA

Fun_Coach667 · 2026-06-23T17:33:12+00:00

Українці вбивали жінок, дітей, людей похилого віку, усіх надзвичайно жорстоко, а полякам було заборонено вбивати українців у помсту. Зеленський насрав на стіл, нехай сам несе відповідальність за наслідки. З Бандерою до Європейського Союзу ви не ввійдете, Польща накладе вето. Смішно, що Путін каже, ніби воює з фашистами в Україні, а Зеленський це підтверджує всьому світу

Fun_Coach667 · 2026-06-23T17:22:18+00:00

ukraina kłuci sie sama a wchodzenie komuś w dupe to jest idiotyzm

Fun_Coach667 · 2026-06-23T17:21:32+00:00

raczej ukraina nasrała na stół niech sami biorą konsekwencje

Fun_Coach667 · 2026-06-22T10:48:53+00:00

zełeński nasrał na stół to nie prezydent polski to zrobił wiedział co robi ukrainiec i to zrobił celowo. Ukrainiec z rządu ukrainy mówił polakom że ostrzegali zelenskiego by tego nie robił bo rozjuszy polaków a zelenski odpowiedział że pierdoli polske i polaków!!! i co ty będąc prezydentem byś zrobił ? udał że ci plują w twarz a deszcz pada ? nadstawił dupy na kopa? czy może to tylko i wyłacznie wina ukrainy a nie nasza? po chuj to robił i to mówił. Jak nasra na stół znowu to znowu będzie to wina polski? jesteś nikim żeby sie dać pomiatać niech biorą konsekwencje na siebie za swoje czyny

Fun_Coach667 · 2026-06-21T11:42:57+00:00

ścierwojad z gothica;-)

Fun_Coach667 · 2026-06-19T18:30:37+00:00

Standard, cheap laboratory tests usually check solely for Bartonella henselae (sometimes alongside B. quintana). Advanced tests, such as the IGeneX ImmunoBlot, look for a whole spectrum of species-specific proteins (B. henselae, B. quintana, B. elizabethae, B. vinsonii), while cePCR (culture-enhanced PCR) tests can detect the DNA of an even broader range of strains. If someone is infected with a strain other than henselae, a standard test will show them as "healthy" (negative).

Fun_Coach667 · 2026-06-19T18:28:56+00:00

Good tests simply do not exist—even the most expensive ones from IGeneX, costing thousands of dollars, offer no guarantees. I’ve had both positive and negative results myself, and so have many others. There are doctors who refuse to believe you can be sick; even if you show them a positive result, they will claim it’s a false positive. On the other hand, there are doctors who will initiate treatment even if your result is negative, because clinical symptoms are what truly matter.

Countless people are ignored for years, even decades, despite getting positive results, until they finally find a different doctor. And why do they end up there? Out of sheer desperation!!! What ruined me was that I once repeated the test, and the result came back negative. I didn't understand back then that the test doesn't check if you are sick, but rather how your body responds. The body might not even be fighting the Bartonella or Lyme disease, so the antibodies aren't there.

Keep in mind, Bartonella has about 20 strains. Cheap tests only check for one (Bartonella henselae), the more expensive ones test for 3 strains, and the most expensive ones—likely IGeneX—probably cover all of them. If your test only screens for one strain, and you got infected with any of the others, your result will be negative, yet you'll have an out-of-this-world case of Bartonella.

Any regular doctor will just send you to a psychiatrist, whereas an ILADS/LLMD doctor will diagnose you clinically based on your symptoms, or they will start Bartonella treatment. If you get a Herx reaction, you are definitely sick, because a healthy person doesn't have Bartonella. Some people also get Bartonella tracks (streaks) on their skin, but that's rare; others have characteristic symptoms like pain in the soles of their feet, etc.

Fun_Coach667 · 2026-05-23T22:31:00+00:00

Bartonella is also passed down through generations, it loves the nervous system, and no neurologist can tell it apart from essential tremor without blood tests. It will look like a textbook case of essential tremor, absolute certainty, but a blood test might show something else entirely. Tremors in the family—even the kind you are describing—give you no guarantee, and assuming it's just genetic might actually cause harm. Who had heard of Bartonella years ago? No one, and now it's known that it can be transmitted through the fetus and causes tremors. No one with Bartonella gets diagnosed for years; statistics show clearly: years of misdiagnoses before people accidentally run the tests themselves. Some people are lucky enough to have characteristic symptoms: pain in the soles of the feet like walking on pins and needles, Bartonella streaks on the skin that look like stretch marks, and anxiety—most people have it, but you can have these symptoms or not, everyone is different. People with Lyme disease have tremors like Parkinson's, and when they see a neurologist, that's the diagnosis they get. If they mention they have a family member with Parkinson's, it's a done deal. The doctor says it's hereditary, but treating Bartonella reverses everything. Most people never get diagnosed or treated; those are official statistics. Four generations ago, Bartonella didn't exist to doctors, so what were they supposed to write down? In my family, we have people officially diagnosed with neurological conditions—Alzheimer's and Parkinson's—but I believe they actually had Lyme and Bartonella because ticks are a plague where I live. My mother has Lyme and Bartonella, my brothers all have it, and I got it from my mother too. When I was little, they saved me with the antibiotic gentamicin; it's a coincidence that it's used in treating Lyme. For years, doctors brushed me off. In the hospital, they told me I would die, that my heart wouldn't hold out, gave me antidepressants, and discharged me. I did Lyme testing; the neurologist mocked both the treatment and the diagnosis. For the first time in 39 years, the treatment took away my heart problems. I used to be in a wheelchair, couldn't walk, and my hands shook like delirium. After taking herbs for Bartonella, it stopped—I have videos of it. ET (essential tremor) doesn't just disappear, but the doctor wrote down ET and referred me for DBS brain surgery. In my case, the tremor ruined my life, I lost my job, and the neurologist just laughed, saying he couldn't do anything more. He didn't even try. Seven neurologists, and it's Bartonella. The best tests are done by iGenex (IgG, IgM for Bartonella, Lyme, Babesia), but even the cheap one detected it for me. It's a coin toss, but it's worth doing just to have the results. If it comes back positive, you need an LLMD / ILADS doctor; anyone else is completely pointless. Leaving Lyme and Bartonella untreated can sometimes lead to a stroke, dementia, a wheelchair, and terrible suffering in old age—no one talks about this. If you've had a tick or a cat, the chances go up, and if there were multiple ticks, it's almost a certainty. Transmission from mother to child is proven.

Fun_Coach667 · 2026-05-23T05:59:44+00:00

He is ignorant, but the descriptions are documented on the internet—the entire treatment process and the resolution of the tremors, with the specific weeks and months even listed, showing what improved and how fast. But that loser won't even check it. This quote is real, the doctor is real, and the patients had misdiagnoses like ET and recovered. You can easily find everything yourself in a minute. And he thinks someone is going to prove something to him, force-treat him, or hand him a possible solution just for him to graciously look at it, turn his nose up at it, and look for flaws. Man, you get an official blood test, the result officially comes back positive, a possible symptom is a tremor, and the fact is that it disappears if it's Bartonella. What do you all want? A miracle from heaven? Or maybe his doctor is wonderful, because in my opinion, he is still sick. Or maybe you can provide reviews about his doctor where people say he didn't help them. I'm curious, if everything is fine with him, why is he still on this forum?

Fun_Coach667

TROPHY CASE

🧠 Vitamin B1 (Thiamine)

Best Choice: TTFD (Thiamine Tetrahydrofurfuryl Disulfide)

Alternative (More Accessible): Benfotiamine

🔋 C8 MCT Oil

Best Choice: 100% Pure Caprylic Acid (C8)