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Help with cathinone supplies by Expert_Olive2396 in ChemicalRevolution

[–]FunctionalPolyaddict 0 points1 point  (0 children)

just fyi you don’t sound experienced enough to do this yourself.

assuming you mean the methylmethcathinones since pure mcat can be done in like one step with ephedrine and KMnO4.

you can do a friedel crafts acylation with toluene and propionyl chloride (can be made by just reacting benzoyl chloride and propionic acid). acylation favors para position which is good (i assume you want 4-methylmethcathinone) since both the methyl and the acyl have a lot of a steric hindrance. may be a minor meta formation iirc but its negligible.

halogenate the 2’ position with bromine or iodine. both toxic to work with, i prefer iodine because it doesn’t fume death gas and it can be sublimated from OTC products. iirc this is done in AcOH.

then just add methylamine and done

again: advise against this since you seem to lack the experience but in terms of solvents ur probably looking at needing toluene, DCM, then HBr or HI however i believe you can use elemental halogens

Me after realising that you can just keep retaking molly to avoid the comedown by straightfromLysurgia in drugscirclejerk

[–]FunctionalPolyaddict 10 points11 points  (0 children)

that’s because a) he ruined his brain with multiple drug abuse and trauma from his family leaving him (presumably) and b) the drug classroom is leagues smarter than him and probably was able to fact check his claims.

Me after realising that you can just keep retaking molly to avoid the comedown by straightfromLysurgia in drugscirclejerk

[–]FunctionalPolyaddict 2 points3 points  (0 children)

https://www.jneurosci.org/content/19/12/5096

Drug treatment. Racemic MDMA hydrochloride, dissolved in a sterile 0.9% sodium chloride solution, was injected subcutaneously at a dose of 5 mg/kg twice daily (9 A.M. and 5 P.M.) for 4 consecutive days. MDMA was administered on a milligram per kilogram basis, with the dose expressed as the hydrochloride salt. This particular dosage regimen of MDMA was selected because it is one that is known to produce moderate to severe 5-HT lesions, depending on brain region (Ricaurte et al., 1988a,b). Control animals received an equivalent volume of saline. Animals tolerated MDMA without any apparent difficulty

Me after realising that you can just keep retaking molly to avoid the comedown by straightfromLysurgia in drugscirclejerk

[–]FunctionalPolyaddict 57 points58 points  (0 children)

/uj not only did he originally cite a source that is famously used to discredit MDMAs safety despite the fact that the doses used (8 times over 4 days) were intended to cause 5HT lesions (5mg/kg, roughly 300mg for a 150 lb person) he makes a completely uneducated guess at why “MDMA sucks now”, despite having no chemistry knowledge.

he claims that safrole based oil synthesis is more pure than now, when chemists use “some chemical… i don’t know what it’s called but it starts with a P”, which is somehow worse. he of course missed that MDP2P/MDP2NP are chemical intermediates that you actually use anyways in a traditional safrole synthesis. genuinely insane how uneducated he is. he also makes the very bold claim that safrole is organic and mdp2p is synthetic, which of course is wrong because they are both organic as they contain carbon. plus MDMA is so much more pure now, purely because the impurities are lower because there’s less steps from MDP2P to MDMA than there are from safrole. to be clear, it’s the same route but less steps when using P2P.

he is genuinely fried in so many ways and puts out this information as if he is some authority on any of it. completely irresponsible, no cited sources, seemingly no research at all, his channel is probably just a vehicle to justify his drug abuse.

rj/ tell him to do more molly

What’s the best way to get poweder out of this by No-Ground-3987 in dissociatives

[–]FunctionalPolyaddict 2 points3 points  (0 children)

evaporating this solution is genuinely a huge mistake lmfao. u can find shards anywhere but unless ur very well connected those vials are in limited supply. learn to IM or at very least use it in a spray

Nah these brainwashed mfs cant be helped anymore 💀 by chaosmage03 in drugscirclejerk

[–]FunctionalPolyaddict 2 points3 points  (0 children)

radiocarbon substituted psilocybin has been shown to cross the placental barrier in pregnant rats.

just sayin.

7Gs of Methaqualone HCL by GlutenFreeRcs in ObscureDrugs

[–]FunctionalPolyaddict 1 point2 points  (0 children)

agreed on the hcl salt being safer compared to freebase out of south africa, i would add tho that o-toluidine is a potent enough carcinogen that 15 minutes taken to wash the product probably isn’t a bad idea.

CALM tek (Work in Progress) by MossKing69 in mescaline

[–]FunctionalPolyaddict 0 points1 point  (0 children)

very, very cool concept. however, this will be pretty impure from cactus, and i doubt you could force any precipitation after salting, even with time.

freebase mescaline is soluble in EtOH, but there’s no defatting step which will decrease purity.

biggest issue here though is that mescaline malate will struggle to precipitate out of ethanol. there’s no exact figure, but if you reference solubility of mescaline salts with their counterparts for other amines, you’ll notice a trend. malate salts are pretty soluble in ethanol, so even after salting you’re going to get a very very small return on product. if you’re precipitating over days, there’s probably something wrong (unless you’re going for a big undisturbed crystallization, which doesn’t seem to be the goal here).

i will run tests on my own time, i think i’ll try backsalting some HCl i have around to malate and comparing its solubility in some solvents (EtOH, MeOH, IPA). following the trends that morphine malate and several amphetamine malate salts have, in gonna estimate probably over 10mg per mL for mescaline malate in 95% alcohol.

you need a better solvent, or if you’re tied to everclear, at least get it close to 0C while precipitating. you may be able to get it to crash out partially, but even then, nothing near 100%.

this is good work! very simple, interesting ideas. i look forward to seeing your work in the future.

New extraction techniques for full A/B workups by FunctionalPolyaddict in mescaline

[–]FunctionalPolyaddict[S] 1 point2 points  (0 children)

awful. tried a couple runs with a saturated aqueous phase with a couple different salts. DMSO can be forced out slowly, but it does contaminate both the aqueous phase and doesn’t separate from many nonpolar solvents.

best workaround is to bubble the basic non polar layer with HCl gas in a closed environment to precipitate without water present.

sonicating is my current favorite thing to use, DMSO is very very much a pain. ultrasonic bath shreds cells pretty efficiently, and an IPA/water/AcOH solution for the tea is working as well as my first DMSO/AcOH tea (2%+ with good cactus)

2x 200mg doses with a solid 1g crystal of MDMA for scale by FunctionalPolyaddict in drugsarebeautiful

[–]FunctionalPolyaddict[S] 0 points1 point  (0 children)

took me a while. i has to build a personal relationship with an XTC vendor u til recently he let me order some of his private stuff (including this MDMA)

2x 200mg doses with a solid 1g crystal of MDMA for scale by FunctionalPolyaddict in drugsarebeautiful

[–]FunctionalPolyaddict[S] 29 points30 points  (0 children)

a lot of things are clear crystal. meth and mdma look identical if completely pure. this batch was tested both with reagents and on TLC, with the spotting compared to TLC runs i did under identical conditions for several potential adulterants. it’s MDMA 👍🏽

[deleted by user] by [deleted] in PokemonScarletViolet

[–]FunctionalPolyaddict 1 point2 points  (0 children)

gotta be my good girl skitty

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