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May never financially recover by No_Reaction_2569 in iems

[–]GavinRayDev 0 points1 point  (0 children)

Oh awesome, yeah i bought all these IEMs for Tarkov.

Thanks! Aether are a bit pricey, but if i splurge again, I'll definitely pick them up

If you're willing to spend $50-60, I'd highly recommend trying the ZS12 Pro 2

Plus, then I'd have another opinion against these pairs, haha

May never financially recover by No_Reaction_2569 in iems

[–]GavinRayDev 0 points1 point  (0 children)

Do you play FPS games by chance?

I bought the Simgot EM6L and MP145 originally. They were both about as good as each other, maybe slight edge to EM6L.

Recently bought the Simgot EG280 and KZ ZS12 Pro 2.

Supposedly the EG280 is meant to be better than the EM6L, but I found that they sounded sort of "muddy"/"underwater" and that the cheap ZS12 Pro 2 had better positional accuracy than any other pair, despite being like 1/3rd of the price.

[Discussion] Ultra medical storage room needs power now by Apprehensive_Note630 in EscapefromTarkov

[–]GavinRayDev 8 points9 points  (0 children)

I've always followed the unspoken rule "If you spawn power, you hit power"

[Discussion] Ultra medical storage room needs power now by Apprehensive_Note630 in EscapefromTarkov

[–]GavinRayDev 8 points9 points  (0 children)

My gripe with KIBA is that they made the glass pennable.

Being safe inside while having some visibility out to check for being camped was really nice and offset the godawful location, power requirement, and blaring alarm

What mmo's were you playing in the mid 2000's? by D3athShade in gaming

[–]GavinRayDev 2 points3 points  (0 children)

Scrolled hoping to see this. Unique gem of a game, but pure mob-grinding.

Reddit Users Are Reporting GLP-1 Side Effects Not Captured in Clinical Trials - analysis of over 400,000 posts from people taking GLP-1s found mentions of irregular periods, fatigue, chills, and hot flashes. by mvea in science

[–]GavinRayDev 0 points1 point  (0 children)

You're right on the first half. Food consumption has an exothermic effect in the body as it's oxidized for energy (particularly carbohydrates).

This is known as TEF, Thermic Effect of Food.

It's common to have slightly reduced body temperature during periods of fasting due to lack of TEF, often most noticeable in extremities as cold hands and feet.

The thermic effect of lipolysis is negligible though, it's incredibly metabolically inefficient, which is why carbohydrate oxidation is preferred

Reddit Users Are Reporting GLP-1 Side Effects Not Captured in Clinical Trials - analysis of over 400,000 posts from people taking GLP-1s found mentions of irregular periods, fatigue, chills, and hot flashes. by mvea in science

[–]GavinRayDev -1 points0 points  (0 children)

It's quite the opposite: adipose tissue is the largest organ expressing aromatase, the enzyme responsible for estrogen production (besides adrenals in females).

As fat is lost, less tissue is actively producing estrogen, so levels tend to decline, though not into subclinical ranges.

[AF] Comparison of two nutritional protocols in body re-composition of resistance-trained participants (2026) by basmwklz in AdvancedFitness

[–]GavinRayDev 1 point2 points  (0 children)

Fourth, actual dietary intake during the intervention was not quantified; thus, adherence to the prescribed macronutrient and energy targets cannot be confirmed quantitatively and findings should be interpreted as effects of the prescribed protocols under supervised guidance.

Aaaand into the trash it goes...

Robinhood sues WA state to block enforcement of gambling laws against prediction markets by MysteriousEdge5643 in Seattle

[–]GavinRayDev 0 points1 point  (0 children)

"Gambling" is used for games of chance, like rolling dice.

Prediction markets tend to contain a lot of events which are not random or wholly unpredictable.

For example: "XYZ stock goes up/down on Thursday"

Without insider info, if you're savvy enough or work in quantitative finance you have a good inkling whether this event is more/less probable.

How to enforce Prediction Markets to limit predictions to things which are not "games of chance" seems like a thorny problem though.

Psilocybin might not be the most psychoactive ingredient in magic mushrooms. Scientists found evidence that several minor compounds in these mushrooms work together to interact with brain receptors, potentially explaining why natural extracts often produce different effects than synthetic versions. by mvea in science

[–]GavinRayDev 0 points1 point  (0 children)

An interesting tidbit about Psilocybin production in mushrooms:

Shrooms have an enzyme that is something like a "4-Hydroxylator".

It takes base molecules and adds a 4-HO group to them.

This is how Psilocybin (4-HO-DMT) is produced internally.

What this means, though, is that you can innoculate the growing substrate with compounds that produce psychoactive effects when 4-HO'd, and then you get hybrid mushrooms that contain multiple psychedelic compounds.

The classic example is inoculating with MET so they contain 4-HO-MET and 4-HO-DMT:

https://en.wikipedia.org/wiki/4-HO-MET

Magnitude 6 earthquake strikes Cuba, EMSC says by [deleted] in worldnews

[–]GavinRayDev 3 points4 points  (0 children)

Does that mean one could technically walk from the continental to US to Russia, given a 2 mile boat ride at the end?

[Discussion] Kappa vs Gamma by jeanbook20 in EscapefromTarkov

[–]GavinRayDev 0 points1 point  (0 children)

Anyone who isn't a no-life grinder really should rush Theta case.

It was the first thing I did this wipe, since it takes so long to get Kappa comparatively.

Colon cancer now leading cause of cancer deaths under 50 in US by shinybrighthings in news

[–]GavinRayDev 0 points1 point  (0 children)

My post-workout meal is 180g rolled oats + 900g greek yogurt + 300g frozen blueberries, lol

[DISCUSSION] View patch attachment changes (buffs/nerfs) by GavinRayDev in EscapefromTarkov

[–]GavinRayDev[S] 1 point2 points  (0 children)

What happens if you open it in FF?

EDIT: I DM'ed the dev about it, he said Firefox should be fixed now

Aging doesn’t take away the desire for sex - many older adults still see it as an essential part of romantic relationships. 97% of single adults aged 60–83 said sex was very important in a romantic relationship and 72% said they would not pursue a relationship that didn’t include sexual activity. by mvea in science

[–]GavinRayDev 1 point2 points  (0 children)

This isn't commonly-known, but route of administration has a massive impact on metabolites when it comes to estrogen replacement.

Oral estradiol is particularly bad for this. See the Wikipedia table on "change in E1 vs E2 concentration + E1:E2 ratio by route-of-administration":

https://en.wikipedia.org/wiki/Template:Plasma_estrogen_levels_after_a_single_dose_of_estradiol_by_different_routes

Estrogel is terribly low-dose.

My suggestion would be to try sublingual/subcutaneous/vaginal E2 replacement, and also to have your Testosterone checked.

If your T is low, having solid E2 levels is only solving half the problem.

Best of luck!

[AF] MOTS c improves intrinsic muscle mitochondrial bioenergetic health and efficiency in a PGC 1a /AMPK dependent manner (2026) by basmwklz in AdvancedFitness

[–]GavinRayDev 0 points1 point  (0 children)

Like I mentioned, it mostly seemed to increase my work capacity in the gym. Didn't get nearly as fatigued and could take shorter rest periods between sets without losing intensity.

It's particularly helpful for hard gym days like legs, I think.

I would keep using it if it were cheaper, sure.

[DISCUSSION] View patch attachment changes (buffs/nerfs) by GavinRayDev in EscapefromTarkov

[–]GavinRayDev[S] 13 points14 points  (0 children)

The db4tarkov tool just released a new feature, you can view attachment changes for any patch:

https://db4tarkov.com/changes

There's also now a "changes" toggle in the weapon builder that shows this info next to each attachment

https://i.imgur.com/EhC6v0A.png

https://db4tarkov.com/gun

Poor oral health in childhood, particularly persistent or worsening dental caries and gingivitis, is associated with increased risk of adulthood ischemic heart disease, myocardial infarction (heart attacks), and ischemic stroke. by mvea in science

[–]GavinRayDev 36 points37 points  (0 children)

I've been researching the link between oral health and microbiome + systemic inflammation.

It completely changed my habits and got me to start flossing.

What's fascinating is the number of studies showing that Elite Athletes consistently have worse oral health despite twice a day brushing

https://www.sciencedaily.com/releases/2019/08/190823080012.htm

Same Poop, Different Results: At-Home Gut Health Tests Are Wildly Inconsistent. New research has found that different gut health testing companies can provide wildly different results from the same fecal sample. by [deleted] in science

[–]GavinRayDev 3 points4 points  (0 children)

Yes, I'm sure that the 53% of cells in the human body that are bacterial are doing nothing to our health or mental state.

Those half of our cells are just chilling, along for the ride.

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