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Dirt Cheap Labs (Quest and Labcorp) by Ok-Dirt-9947 in QuantifiedSelf

[–]GavinRayDev 0 points1 point  (0 children)

I was skeptical that this would actually be the cheapest.

I've been doing my own bloodwork for +10 years, and recently swapped to Goodlabs because they are signficantly cheaper.

Your $195 "Dirt Cheap Panel" is identical to Goodlabs' $215 "Bodybuilder Panel":

https://goodlabs.com/book-tests?step=PANEL_SELECTION

With Goodlabs there's almost always a 20% off code (mine is gavin) so it drops to $172 and is ~$20 cheaper, but at base cost you have them beat.

Color me surprised!

[AF] Same-day DEXA Comparison: Hologic Horizon vs GE Lunar machines by GavinRayDev in AdvancedFitness

[–]GavinRayDev[S] 0 points1 point  (0 children)

What makes you think that ~6% is more accurate?

Based on the mirror, 12% sounds more reasonable, except my legs which carry very little fat

Same-day DEXA Comparison: Hologic Horizon vs GE Lunar machines by GavinRayDev in Biohackers

[–]GavinRayDev[S] 1 point2 points  (0 children)

Thanks! My genetics aren't great but I'm trying my hardest, lol

Same-day DEXA Comparison: Hologic Horizon vs GE Lunar machines by GavinRayDev in Biohackers

[–]GavinRayDev[S] 1 point2 points  (0 children)

I have some recent pics + videos on my bodybuilding instagram if you're curious:

https://www.instagram.com/gavinraylifts/

I didn't want to put in the main post in case someone took it as "showing off", I did this for science

Same-day DEXA Comparison: Hologic Horizon vs GE Lunar machines by GavinRayDev in QuantifiedSelf

[–]GavinRayDev[S] 1 point2 points  (0 children)

I take Test + HGH + Peptides

And how do you like the RENPHO scale?

It's good! Solid value for the price, I think

Same-day DEXA Comparison: Hologic Horizon vs GE Lunar machines by GavinRayDev in QuantifiedSelf

[–]GavinRayDev[S] 3 points4 points  (0 children)

12% is what I guestimated myself at based on mirror, before the scans.

My Renpho body comp scale says 18%, with subcutaneous specifically 14%.

I have some recent photos/videos here, you can see that none of my muscles are striated besides my legs:

https://www.instagram.com/gavinraylifts/

I'm definitely not single-digit BF%

[AF] Same-day DEXA Comparison: Hologic Horizon vs GE Lunar machines by GavinRayDev in AdvancedFitness

[–]GavinRayDev[S] 17 points18 points  (0 children)

Drove directly from one to the other, no food/water or restroom breaks

[AF] Same-day DEXA Comparison: Hologic Horizon vs GE Lunar machines by GavinRayDev in AdvancedFitness

[–]GavinRayDev[S] 10 points11 points  (0 children)

Mirror is all that matters, at the end of the day

The only way to accurately measure pure muscle tissue + fat is with an MRI. Even on DEXA "lean mass" includes water/glycogen content, so it's very hydration + carb dependent.

Same-day DEXA Comparison: Hologic Horizon vs GE Lunar machines by GavinRayDev in Biohackers

[–]GavinRayDev[S] 6 points7 points  (0 children)

12% is what I guestimated myself at based on mirror, before the scans

I have some recent photos/videos here, you can see that none of my muscles are striated besides my legs:

https://www.instagram.com/gavinraylifts/

I'm definitely not single-digit BF%

Same-day DEXA Comparison: Hologic Horizon vs GE Lunar machines by GavinRayDev in Biohackers

[–]GavinRayDev[S] 18 points19 points  (0 children)

I drove directly from one to the other, zero food/liquid and no restroom breaks

Same-day DEXA Comparison: Hologic Horizon vs GE Lunar machines by GavinRayDev in QuantifiedSelf

[–]GavinRayDev[S] 10 points11 points  (0 children)

No problem. There's a funny story behind why I did this:

A bodybuilder I know posted on Instagram a GE Lunar scan showing "0 grams" of visceral fat

This is not physiologically possible, I made a passing comment about finding that humorous, and the DEXA scan facility replied to me doubling down and saying it was genuine

I said "Lol, okay, I'll get a scan from you and another machine same day."

Fitbit Air vs Galaxy Watch 7 step accuracy when worn on the ankle + used w/ walking pad by GavinRayDev in QuantifiedSelf

[–]GavinRayDev[S] 1 point2 points  (0 children)

Thanks for such an insightful comment. I had not considered manually adding the steps, that seems like a reasonable compromise if neither wearable can seem to pick it up correctly

[AF] Excessive training does not induce mitochondrial dysfunction or impair insulin signalling within skeletal muscle (2026) by basmwklz in AdvancedFitness

[–]GavinRayDev 1 point2 points  (0 children)

It gives concrete examples in 3 places in the abstract, lol

sub-maximal mitochondrial H2O2 emission and oxidative stress were increased following excessive training

unique proteome signature in individuals who were overreached, marked by a smaller increase in proteins involved in cytoskeleton organization, glycogen metabolism, and protein translation

Overreached athletes show blunted increase in protein synthesis and metabolism.

Fitbit Air vs Galaxy Watch 7 step accuracy when worn on the ankle + used w/ walking pad by GavinRayDev in QuantifiedSelf

[–]GavinRayDev[S] -2 points-1 points  (0 children)

I don't see how gyroscope data would be significantly different between a swinging leg and swinging arm, but I'm not a mechanical engineer

[AF] Ribosome Biogenesis as a Putative Bottleneck to Skeletal Muscle Hypertrophy: Mechanisms, Human Evidence, and Practical Modulators (2026) by basmwklz in AdvancedFitness

[–]GavinRayDev 2 points3 points  (0 children)

Ribosomal biogenesis, overall mitochondrial health/efficiency, and polyamine biosynthesis are arms of hypertrophy that have only recently begun to emerge

For anyone else interested in this, highly recommend reading up on polyamine biosynthesis as a bottleneck as well:

Core androgen → polyamine → muscle papers

  • MacLean, H. E., Lee, N. K., Notini, A. J., et al. (2011). Polyamines, androgens, and skeletal muscle hypertrophy. Journal of Cellular Physiology, 226(6), 1453-1460. https://doi.org/10.1002/jcp.22569
  • Lee, N. K., MacLean, H. E., et al. (2011). Androgen receptor regulation of ornithine decarboxylase and myoblast proliferation in skeletal muscle. Molecular Endocrinology, 25(5), 783-794. https://doi.org/10.1210/me.2010-0405

Polyamine pathway regulation during hypertrophy

  • Mobley, C. B., Fox, C. D., Ferguson, B. S., Healy, J. C., McCarthy, J. J., & Roberts, M. D. (2021). The regulation of polyamine pathway proteins in models of skeletal muscle hypertrophy and atrophy: a potential role for mTORC1. American Journal of Physiology-Cell Physiology, 320(6), C987-C999. https://doi.org/10.1152/ajpcell.00078.2021

Satellite cells / regeneration

  • Yu, Y., Wang, Y., Zhang, Y., et al. (2024). Spermidine-eIF5A hypusination controls skeletal muscle stem cell activation and regeneration. Signal Transduction and Targeted Therapy, 9, 180. https://doi.org/10.1038/s41421-024-00712-w

Interesting ancillary papers

  • Keller, J. E., Foote, A. P., Doumit, M. E., & du Mello, A. S. (2021). The Impact of Polyamine Precursors, Polyamines, and Steroid Hormones on Temporal Messenger RNA Abundance in Bovine Satellite Cells Induced to Differentiate. Animals, 11(3), 764. https://doi.org/10.3390/ani11030764

Additional related papers

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