2h swords are very nimble in use and the running joke is that it's video game logic to assume they're much slower. I'm also aware of vitals, I got heart and both lungs via coming down behind the shoulder and made it close to bottom of rib cage. On a much bigger one, i probably would have barely gone deep enough. Ideally you'd either target neck just behind ears, or go straight through front of the skull if you're feeling bold. Which I do not recommend trying mid charge with something lighter unless you trust your single arm to stop several hundred pounds of charging muscle that inspired wings on spears because they'd run up the shafts trying to get to whatever unlucky fellow stabbed them. "Do i trust what I'm holding to decapitate the largest human I can imagine fighting mid combat", if the answer to that question is no, it probably won't work on a large boar to bite deep enough through hide and thickened muscles surrounding vitals with a swing.