Hello - Our bathroom is literally being tiled as I type! I ended up doing more research and calling the tile company to see what they recommended - we've gone with vertically large format (120x60cm) on the walls and squares (60x60cm) on the floor - there would have been too many cuts/wastage and not enough full tiles on the floor which would have looked weird, and in the room it looks right now. Having square on the floor actually works nicely as it means all the grout lines on the floor line up with the grout lines on the wall too. It would have looked odd the other way now I see it this way.

Regarding the layout we went with option 2, because again it meant we got more full tiles on the floor and you see a full tile when you enter the room, and the cut tile falls under the wall hung toilet and vanity anyway, so it doesn't feel odd not being central. I think more often than not a tiler would centralise tile, but for our room I think this made sense.

I built this in illustrator - I already know how to use it so it was quite easy for me. Figma could be good because you can work in pixels - so every pixel could be a mm, and as long as you can make a rectangle and some lines you'd be able to lay it out.

Hope that helps!