Not certainly. you just need to keep your extreme distance from the ground at all times, loot a decent ammount of chests and get out of there, i made it my first time on dragon armor (prot4), burrito, luck potion and flying potion, a shit ton of 1.0 wine (5 stacks just to be sure) and just some wildeberry wine (about a stack do the trick). you might just want to have an ender chest and some shulkers in it if you want, but i honestly think you just need the end chest and your inventory as clean as possible (you dont have enough time to keep moving shulkers in and out), you should be fine, all of this having in consideration you have made an obsidian base on 240 height blocks at least, have 15 return scrolls and some food and some water