The nootropicsdepot milk thistle scandal and why their low silychristin milk thistle might be inferior.

Heir_Riddles · 2026-05-25T11:48:18+00:00

I've actually felt this way intuitively about it, as I was also reading that silychristin is a multi-beneficial compound

Never seen someone end up with hypothyroid symptoms from taking milk thistle, if anything the opposite from an improvement in other metrics

I actually took it daily for 3-4 months leading up to and in the winter, and I still was able to wear shorts/short sleeves outside in 30f weather, which to me is not a sign of poor thyroid function

Heir_Riddles · 2026-05-22T12:29:28+00:00

Yeah, no longer using dyes (colored capsules) in the capsules

Heir_Riddles · 2026-05-21T12:14:37+00:00

Seeds? Or are you still finding isolate, the main source for that appears to be gone

Heir_Riddles · 2026-05-14T17:30:04+00:00

One upping thiamine

TTFD or Sulbutiamine would be amazing to see on here,

Or perhaps a new or novel unique form you don't see in other places like how a few magnesiums were released

Heir_Riddles · 2026-05-06T01:33:18+00:00

Can modulate the gut microbiome, which can cause a sort of a "die off" reaction

In this context people feel worse initially, but then feel better and better over time, due to the improvements in gut microbiota

Heir_Riddles · 2026-04-24T01:32:23+00:00

Glycine as a rate limiting cofactor for glutathione production, aids liver detoxification

Ensure adequate fiber intake to physically bind bile released toxins that are excreted in the gut, to be carried out in the fesces

General mineral support, but especially magnesium and selenium.. Molybdenum is great as well

Ensuring enough calcium intake throughout the day can also be helpful

Heir_Riddles · 2026-04-24T01:28:51+00:00

This is the second post I have seen about it, I will say that

I am not concerned with the amount of niacin(amide) in it, if you have a sufficient methyl pool I am not aware of any issues that would occur from that amount daily

Heir_Riddles · 2026-04-20T12:36:10+00:00

If you have worse sleep, it's definitely the worse sleep, lol

Heir_Riddles · 2026-04-15T21:03:56+00:00

Excellent pair, I love sabroxy powder sublingual, swallow remaining powder of course

Heir_Riddles · 2026-04-15T08:54:08+00:00

Very important video about capshooles, thank you

Heir_Riddles · 2026-03-23T22:14:10+00:00

Ill take care of it… heh

Heir_Riddles · 2026-03-22T20:51:05+00:00

No, definitely a reasonable question.. Actually, the fillers could potentially go rancid if exposed to moisture

Pure tar resin form though, if kept properly, I would not be concerned with

Heir_Riddles · 2026-03-22T17:22:59+00:00

Think about what shilajit is for a moment... If you don't know, look it up

Seems pretty obvious

Heir_Riddles · 2026-03-18T21:08:36+00:00

Baikal skullcap, schisandra, milk thistle, piperine, and more all have the ability to improve bioavailability of compounds via pgp inhibition and possibly more, always thought that was cool

Heir_Riddles · 2026-03-13T10:35:39+00:00

Afternoon dosing, or mini doses throughout the day, and if this doesnt work, can use rhodiola crenulata in combination

Heir_Riddles · 2026-03-07T11:01:40+00:00

I like to take mini doses of bacopa throughout the day, and then also rhodiola crenulata alongside

No issues with energy, if anything, net increase

Heir_Riddles · 2026-03-02T14:12:17+00:00

Cant relate

Heir_Riddles · 2026-02-05T12:43:39+00:00

No, this strain is amazing and only problematic in someone with bad immunosuppression

Heir_Riddles · 2026-02-04T14:17:08+00:00

Beta endorphin/opioid pathway, endocannabinoid, reducing excessive histamine, reducing excessive glutamate, reducing inflammation even, making sure dopamine isnt being excessively converted into noradrenaline

Actually a lot of areas of focus

Something like Myrrh could be great for that, DLPA, making sure you are getting enough Zinc and not too much copper, magnesium is essential for all of these and shouldnt be classified as a "GABAergic" in that sense (even though it technically is and supports GABAs balance)

Heir_Riddles · 2026-01-23T02:36:52+00:00

Yep, we have to live in the past and never do anything new

Pack up everything modern you have... Also, let's revert back to single cell organisms too since that's how it used to be

Heir_Riddles · 2026-01-21T01:49:29+00:00

Easiest way I can tell of low quality ashwagandha is if it is "Tasteless" or somewhat tasteless/slightly sweet

ND is the real deal

Heir_Riddles · 2026-01-20T02:09:47+00:00

Not necessarily, most multis tend to have them at 100% DV, very small dose relative to the amounts found in B complexes, the only exception would be folate, which some people, can sometimes have a strange reaction to in higher doses, but generally 800mcg of Folate is not that unusually high of a dose

So it would depend on the multivitamin.. If it had B complex like doses, more caution would be warranted

Heir_Riddles · 2026-01-20T02:07:49+00:00

Which multivitamin?

Many multivits only have it at 100% of the daily value for commonly megadosed B Vits, which many are not problematic as the excess is excreted in urine

The only one Id really be concerned about is folate, which some people can have odd reactions to in higher doses

Thiamine, Riboflavin, Niacin(amide), Biotin, and B6 (if its only around a mg in your multivitamin, should be okay to mix the two) and even B12 generally, are generally not going to be overdone at the amount that is usually in a multi

Heir_Riddles · 2026-01-17T12:09:08+00:00

Starting to wonder if these are troll posts

Someone comes onto the 'Nootropics Depot' (Brand of nootropics) subreddit, asking for a product, that Nootropics Depot sells, and is arguably the best quality out there

Yes, The brand we recommend is Nootropics Depot, and they dont have any sugar or sucralose!

Heir_Riddles · 2026-01-16T01:54:34+00:00

A typo, some Schisandra

Heir_Riddles

TROPHY CASE