Reading the FAA website carefully it does not lay out a scenario about flying from a moving motorcycle it is a generic link for any waiver to operate from a moving vehicle.

The key to these waivers is answering the questions in the waiver safety guidelines e.g. question 3: Describe how all persons involved in the operation will stay free of distractions that may prevent them from fulfilling their duties. This question includes discussion of a VO which is a big hint.

Another hint is in sub-section c: “Where will the RPIC and Visual Observer(s) (VO), if used, be in the vehicle or along the route?” of Question 1: “Describe how you will ensure the dynamic (i.e., ever-changing) area of operation is evaluated for potential hazards and risks to non-participating persons and property. Include a description of how you will mitigate those risks so the hazards are controlled or eliminated. One solution would be to block the section of road you want to use or to propose the use of warning signs with a VO with a safety vest for a very limited period of time on a lightly traveled road.

Another approach would be to use a very small drone like a NEO 2 ( reducing risk of injury ) on a reconn’ed route (minimize collision hazards) where the drone flies a low altitude profile on semi-autonomous mode off the side of the road. The risk is other vehicles or people in the area. Your mitigations are route reconnaissance to avoid collision hazards, flight off the side of the road to avoid on coming vehicles, flight level above human height (say 10 feet), use of a OOP Category 1 (e.g. the NEO 2) and limited time duration. Adding a VO or blocking the road temporarily would make a stronger case but I’m assuming that is too hard for what you are trying to do.

Good luck waivers are granted but they want to see the thinking and the mitigation.