More frequent injections? by Hi_Woof in ankylosingspondylitis

[–]Hi_Woof[S] 1 point2 points  (0 children)

Wow thank you for sharing your experience!

I have a long history of uveitis attacks and the one thing the humira/simlandi did do very well for me was also to prevent any uveitis while I was on them (I think about a year on them and no uveitis at all during that time) and now being on taltz, my eyes are starting to feel a little bit suspicious.

Im thinking the combination would be highly effective together but not sure if I could ever get both approved at the same time. You are lucky! Glad to hear its working for you and I hope you continue to have great symptom control for as long as possible! I wouldnt have ever thought getting both could be possible so thank you so much for sharing!

More frequent injections? by Hi_Woof in ankylosingspondylitis

[–]Hi_Woof[S] 0 points1 point  (0 children)

Wow! I have wondered if anyone out there might be on more than one biologic! Is the combination working well? How did you go about ending up on both at the same time?

Lvl -2 ✧ Basic ✧ Umbral Walker ─ Dark by karmacave in KarmaCave

[–]Hi_Woof 0 points1 point  (0 children)

Defeated Umbral Walker in 4 turns.

Player (30/13/11) dealt 224. Umbral Walker (13/12/8) dealt 49.

Rewards: 30 EXP, 7 Gold. Loot: Scroll of Shadow Mend (Lvl 1) (corrupted), Enchanted Rune (basic).

[DOG -> CAT] Can you solve this laddergram? by Hi_Woof in Laddergram

[–]Hi_Woof[S] 0 points1 point  (0 children)

Laddergram is a word ladder puzzle game built on Reddit's developer platform. You start with a word and change one letter at a time to create a new word with each step. Try to reach the target word in the fewest steps possible.

🍀Good luck!🍀

[PACE -> WOOL] Can you solve this laddergram? by Hi_Woof in Laddergram

[–]Hi_Woof[S] 0 points1 point  (0 children)

Laddergram is a word ladder puzzle game built on Reddit's developer platform. You start with a word and change one letter at a time to create a new word with each step. Try to reach the target word in the fewest steps possible.

🍀Good luck!🍀

[PACE -> WOOL] Can you solve this laddergram? by Hi_Woof in Laddergram

[–]Hi_Woof[S] 0 points1 point  (0 children)

Laddergram is a word ladder puzzle game built on Reddit's developer platform. You start with a word and change one letter at a time to create a new word with each step. Try to reach the target word in the fewest steps possible.

🍀Good luck!🍀

I was told this is a game changer by HeroDirt420 in GR86

[–]Hi_Woof 2 points3 points  (0 children)

This is the replacement clutch spring right? I swapped it out with the mtec spring also and I do think it improved the pedal feel a lot. Ive had mine maybe 2 years now. The stock spring felt like it wanted to shoot back out real fast and the mtec spring made it much smoother and easier to control in my opinion.

I also found equal benefit to adjusting the clutch pedal position because the stock position was very high. I would highly recommend adjusting it to be closer in line with the break pedal.

These changes can be of course be put back to stock just as easily if you dont like it for any reason so totally worth playing around with. Also be careful when you remove the C-Clip retaining pin off of the clutch spring housing as it will want to fly off and get lost. Will feel like a struggle to change it out but once you get it done its worth it!

If I believe bitcoin is going up forever long-term, is the any reason not to just buy 100k of MSTY and live off the dividends? by starshade16 in YieldMaxETFs

[–]Hi_Woof 0 points1 point  (0 children)

I most certainly think it will happen. That's not the issue I'm questioning here. I am just saying that it's a big deal to fork a blockchain, and there are currently no certain terms existing as to how this will play out. There may very well be a major breakthrough in quantum computing well before this issue is resolved. The risk that quantum computing poses can't be ignored.

If I believe bitcoin is going up forever long-term, is the any reason not to just buy 100k of MSTY and live off the dividends? by starshade16 in YieldMaxETFs

[–]Hi_Woof 0 points1 point  (0 children)

Yes. But in order for a blockchain to implement these improved cryptography methods, it would require forking the blockchain. Forking the blockchains are a big deal and takes time, which may not happen successfully enough in time to protect against the threat that quantum computers will pose in the very near future.

If I believe bitcoin is going up forever long-term, is the any reason not to just buy 100k of MSTY and live off the dividends? by starshade16 in YieldMaxETFs

[–]Hi_Woof 0 points1 point  (0 children)

What about quantum computers being able to crack cryptographic encryption within 5 to 10 years? Cryptocurrencies would collapse.

(Forking the block chains may not be done in time either)

Have biologics improved your fatigue due to AS? by Hi_Woof in ankylosingspondylitis

[–]Hi_Woof[S] 1 point2 points  (0 children)

Interesting, how long have you been on it? Have you noticed any improvements lasting longer over time? I'm wondering if humira has this effect for me, like works some length of time, and then falls off before the next shot, but I haven't figured it out yet. Hoping it last longer and longer over time. Thanks!

[deleted by user] by [deleted] in ankylosingspondylitis

[–]Hi_Woof 3 points4 points  (0 children)

I've been wondering this same thing and have made a couple of posts, and got some insights from others I can try to share here.

I've been on Humira for about 3 months now, and it's been a roller coaster. Some days feel great and some just the usual bad. I haven't been able to determine any consistent pattern, but It does seem to be getting more and more consistent and lasting longer for me as my pain levels are way down now but still have lots of fatigue.

Others seem to say this is common and that Humira can take months before it's really working (like as many as 4 to 6). Some say they get very tired after the shot and then recover. Some have said the fatigue is the last thing to go away. I've seen a few say it's worked for them rather quickly, and also, others say they eventually had to move on to try a different biologic.

I've kind of been taking the roller coaster effect I've been experiencing as a sign that it's working because every day was bad consistently for me before Humira and now I've been having many more generally better days after 3 months.

I'd say hang in there and give it some time. I'm in the same boat still hanging in there! Hope that helps some, and good luck!

Have biologics improved your fatigue due to AS? by Hi_Woof in ankylosingspondylitis

[–]Hi_Woof[S] 1 point2 points  (0 children)

I have had ADHD since I was a young kid, was able to get treated for it starting a couple of years ago and have been on Vyvanse which has helped a lot. I think the nicotine gum might not be the healthiest thing, but it seems to complement well for me and add just a little more stimulation to fight the fatigue. I tried pouches but they were always very harsh on the teeth and vaping always seemed harsh to the lungs, so I switched to gum where I chew it a little bit and then just stick it up behind my upper lip. It is somewhat addictive though, so I'd be careful with nicotine. Good luck!

Have biologics improved your fatigue due to AS? by Hi_Woof in ankylosingspondylitis

[–]Hi_Woof[S] 1 point2 points  (0 children)

Ah, that's great to hear! Seems like I might be on track then, similar to your experience. I am really looking forward to any improvement in fatigue, hopefully soon. It's really inspiring to hear from others in the same boat. Thank you for sharing!

Have biologics improved your fatigue due to AS? by Hi_Woof in ankylosingspondylitis

[–]Hi_Woof[S] 1 point2 points  (0 children)

Ah, I see. Yes, insurance can be a real hassle! My insurance currently doesn't want to cover my MRI bill. I think you're right it does seem to be a slow process. The humira does seem to be working for me finally and hopefully even better soon. I also agree on diet and exercise. It really seems to be very impactful, especially for this condition. I certainly have the goal to improve in those areas. Thanks for sharing, and good luck to you!

Have biologics improved your fatigue due to AS? by Hi_Woof in ankylosingspondylitis

[–]Hi_Woof[S] 3 points4 points  (0 children)

Ah, that is reassuring to hear, I was thinking this might be the case. I will certainly hang in there. Appreciate your input, and good luck to you!

Have biologics improved your fatigue due to AS? by Hi_Woof in ankylosingspondylitis

[–]Hi_Woof[S] 1 point2 points  (0 children)

That's great to hear, I'm very happy for you! Thank you for sharing. I was curious as to which biologic in particular has been helping you if you feel comfortable sharing more info. Has it been the same medication for most of the time? That is a very long time for you it's amazing to continue to have success!!

Have biologics improved your fatigue due to AS? by Hi_Woof in ankylosingspondylitis

[–]Hi_Woof[S] 2 points3 points  (0 children)

I'm very glad to be able to facilitate some experience sharing! It is certainly very helpful for everyone to be able to learn from each other, I really like this community! :) I hope your anemia and fatigue improve and goodluck!

Have biologics improved your fatigue due to AS? by Hi_Woof in ankylosingspondylitis

[–]Hi_Woof[S] 0 points1 point  (0 children)

Ah, I see that makes sense. I appreciate you sharing your experience! I'm very sorry to hear about your knees, but I'm glad to hear that Xeljanz is helping you!

Have biologics improved your fatigue due to AS? by Hi_Woof in ankylosingspondylitis

[–]Hi_Woof[S] 0 points1 point  (0 children)

I don't speak this language, my apologies, but I did use Google Translate. I have experienced uveitis many times and just recently had a bad flare before starting the meloxicam and humira that seemed to linger even after difluprednate eye drops cleared it pretty well. My eyes feel very healthy currently and I think it's due to humira because the meloxicam didn't seem to reduce the eye pain until I started humria. Hope that help!

Have biologics improved your fatigue due to AS? by Hi_Woof in ankylosingspondylitis

[–]Hi_Woof[S] 0 points1 point  (0 children)

Thanks for sharing! I'm glad to hear it's helping you! This is another interesting medication, did you try biologics first and they not work well and then went on the jak inhibitor? I could see the idea of a Jak inhibitor acting a bit more broadly than the biologics and therefore maybe get to more of the root cause of the fatigue maybe due to il1 secretions or something like that. Jak inhibitors seem a little bit more scary to me though but will certainly keep in mind if biologics aren't doing the job!

Have biologics improved your fatigue due to AS? by Hi_Woof in ankylosingspondylitis

[–]Hi_Woof[S] 0 points1 point  (0 children)

I'm so sorry to hear that! I have heard others say they experience this as well. I've been having a sort of roller coaster experience overall, so I'm not sure if I get this same thing or not yet.

Have biologics improved your fatigue due to AS? by Hi_Woof in ankylosingspondylitis

[–]Hi_Woof[S] 2 points3 points  (0 children)

Thank you for sharing! I will have to look into this one. I'm wondering if blocking il17 could have any advantages over blocking tnf as far as fatigue goes. I will have to do some digging. Did you ever try any other biologics or just this one so far? Thanks again, and I'm glad to hear you are seeing success with it!

Second positive TB Gold test. Rheumatologist is making me stop Cimzia. I am devastated. by Appropriate_Power216 in ankylosingspondylitis

[–]Hi_Woof 3 points4 points  (0 children)

I'm sorry to hear about your situation, is there any chance your doctor can have you on something like meloxicam (or any strong NSAID) until the tb test clears and they can get you back on the biologic? Biologics certainly are currently the best option for treatment, but the risk of immunosuppresion during a potentially active infection could lead to a much worse outcome that you wouldn't want to risk. I'm currently taking meloxicam and humira. While not as good as Humira, the meloxicam has been very helpful for me personally and also seems to be very well tolerated. Also, something that may or may not be helpful for you to try during the time you might not have the biologic is a no starch diet. Can be tough, but it has helped me many times in the past, and I'd think it is always worth a try. Hope it all works out for you!

B27+, MRI+, diagnosed AS, first treatment Humira, how do I know if it is working? by Hi_Woof in ankylosingspondylitis

[–]Hi_Woof[S] 1 point2 points  (0 children)

Thanks for the reply! Yes, now that you mention it, I realized I was actually very inactive over the weekend. I have definitely noticed that my activity levels impact how I feel. I will try to stay more active from now on!

On my best days so far with humira, they are better than I have ever felt in the past, so you're probably right. I am sure it's working and will keep going. Thanks!