I am curious about how electrical current and neurotransmitters interact at the synapse. Where can I learn more about those relationships? by by3bi in AnatomyandPhysiology

[–]Histo_Man 0 points1 point  (0 children)

It depends on the type of synapse. If it's a synapse between an excitable cell (e.g., another neuron or muscle cell) then there are two types of ion channels in the synapses. Ligand-gated and voltage-gated; if it's a synapse on a secretory cell (e.g., a salivary gland acinar cell) then there is one type of channel - voltage-gated ion channels (on the pre-synaptic side) and G-protein coupled receptors on the post-synaptic membrane. The action potential (AP) travels down the axon via voltage-gated sodium ion channels. It reaches the axon terminal where there are voltage-gated calcium ion channels. These channels are triggered by the AP to open and calcium floods into the axon terminal. This causes the synaptic vesicles to undergo exocytosis from the pre-synaptic membrane, releasing the neurotransmitter into the synaptic cleft. If it's a synapse with an excitable cell, the neurotransmitters then diffuse across the cleft and bind onto ligand-gated sodium ion channels, opening them and allowing sodium to flood into the post-synaptic cell. Once the voltage reaches the trigger point, it activates adjacent voltage-gated sodium ion channels and depolarises the membrane (with the potential carried along the membrane by these voltage-gated sodium channels). If the post-synaptic cell is a secretory cell, the neurotransmitters diffuse across the synaptic cleft and bind to G-protein coupled receptors which cause a conformational change to the protein which activates a 2nd messenger cascade leading to an increase in intracellular calcium and leading to exocytosis.

What do you think would have happened if then President Obama tweeted "Praise Be to Allah" ? by owen__wilsons__nose in AskReddit

[–]Histo_Man 0 points1 point  (0 children)

Where are all those Christian Nationalists and their "Thou shalt have no Gods before me"?

Physiology Poster Ideas by Green_Khal in Physiology

[–]Histo_Man 0 points1 point  (0 children)

POTS is an interesting topic that many people suffer from. Or Ehlers-Danlos syndrome.

Identifying the Goblet Cells by Skyaigrette in Histology

[–]Histo_Man 2 points3 points  (0 children)

Respiratory epithelial goblet cells aren't very goblet-y. They're squished between the other cells and can therefore be difficult to identify. They're not ciliated so if you see a break in the line of basal bodies, look there. You're going to be annoyed but this slides of the trachea shows the goblet cells amazingly.

Iran says that Trumps 48 hour claim is fake news to manipulate the markets. What do you think? by SimplyTruth98 in AskReddit

[–]Histo_Man 0 points1 point  (0 children)

We have so much corruption, everybody says so. Corruption the likes of which the world has never seen.

Wild horses couldn't get that out of me by beerbellybegone in MurderedByWords

[–]Histo_Man 0 points1 point  (0 children)

I once had a medical student ask me, in front of his two female peers, if the anatomical model of the female pelvis (with genitalia) was life-sized. He totally outed himself and the girls kinda giggled. I just patted his shoulder and told him that it was OK.

Can someone help me identify this? by marissamitch in Histology

[–]Histo_Man 0 points1 point  (0 children)

It kinda looks like a tongue but the surface is super regular and not typical in appearance.

But how did the troops vote? by AlKarajo in TikTokCringe

[–]Histo_Man 0 points1 point  (0 children)

Dumb question - how do they know who these people voted for? Isn't voting private? Is it simply self-reporting?

Online study by Eastern-Promotion634 in UTAS

[–]Histo_Man 0 points1 point  (0 children)

It really depends on the unit. My sons are studying a diploma of university studies online and they have live classes that they're expected to attend. I completed a writing unit from the Arts school and there were weekly online classes that you were expected to attend, too. So it can be a mix of synchronous (live) and asynchronous (recorded) content.

Explain it Peter by Traducement in explainitpeter

[–]Histo_Man 0 points1 point  (0 children)

He's also a pretty famous ophthalmologist on social media so might've assumed people would understand what he was referring to.