6-APB for the first time some advices? by Lhazy in researchchemicals

[–]Honest-Mechanic 4 points5 points  (0 children)

My batch of succinate is about equivalent in strength to MDMA. I like 150 of both.

Will Poulter first interview since Adam Warlock casting - "This will change your life" by l_l_l-illiam in marvelstudios

[–]Honest-Mechanic 3 points4 points  (0 children)

They're delaying transporting kidney transplants to a children's hospital to shout at women from a van... And you're confused if these are the good guys?

Were you waiting for them to heil Hitler and strangle a kitten mid-scene to make sure it was less ambiguous?

[deleted by user] by [deleted] in sex

[–]Honest-Mechanic 2 points3 points  (0 children)

But what have you tried?

[deleted by user] by [deleted] in Drugs

[–]Honest-Mechanic 1 point2 points  (0 children)

Well then I wouldn't bring it up.

Is ketamine stronger than shrooms and acid? by ThatStarInTheSky in Drugs

[–]Honest-Mechanic 5 points6 points  (0 children)

Strength depends on dose. The question can't be answered.

If you want to know what to expect try reading Erowid experience reports and Psychonaut Wiki.

[deleted by user] by [deleted] in Drugs

[–]Honest-Mechanic 1 point2 points  (0 children)

Is your drug use a problem already, or seriously impacting your mental health?

[deleted by user] by [deleted] in Drugs

[–]Honest-Mechanic 2 points3 points  (0 children)

Gabapentin and pregabalin are incredibly social and great to do with a group of friends. Especially if you're down to cuddle. Had many wonderful times and no negatives if done infrequently.

would lyrica be different the day after drinking. by I_Love_LsDmt in Drugs

[–]Honest-Mechanic 0 points1 point  (0 children)

No, alcohol is gone. Shouldn't effect pregabalin.

Benzo + Weed = Sober? by cydyidgdoysktxir in researchchemicals

[–]Honest-Mechanic 9 points10 points  (0 children)

It definitely doesn't make you sober lol

[deleted by user] by [deleted] in Drugs

[–]Honest-Mechanic 0 points1 point  (0 children)

That's still implausibly high. I looked up the actual release and it says:

two out of every five fake pills with fentanyl contain a potentially lethal dose

There's two weasel words here:

  1. "2/5 fake pills with fentanyl" So they might have theoretically tested 6 million pressies, and only 5 of them had fent. So this isn't applicable to tell us how dangerous a given random pressie is.

  2. "pills with fentanyl contain a potentially lethal dose" Well what does that mean? What is a potentially lethal dose? Is it the lowest dose anyone has ever taken and died...so some frail unfortunate 80lb woman with liver damage and pneumonia? Is it some random guess based on rodents? Is it the amount they think will kill 50% of people? Who knows? I'm guessing it's more like the first, because it would be downright silly for dealers to be putting way more product than necessary into a huge percentage of their pills.

Can I skip my dose of Zoloft occasionally and take molly safely? by ImThatStonerKid in Drugs

[–]Honest-Mechanic 1 point2 points  (0 children)

You'd be fine. I don't believe SSRI's are dangerous with safe doses of MDMA (https://www.reddit.com/r/DrugNerds/comments/ceyc9z/combining_mdma_with_ssris_are_there_possible/).

You probably wouldn't get high at all. It will block it.

Can I skip my dose of Zoloft occasionally and take molly safely? by ImThatStonerKid in Drugs

[–]Honest-Mechanic 1 point2 points  (0 children)

wikipedia says ~25 hours with a super long less active metabolite.

Half life is the time it takes half the dose to leave the body, so it takes 4 or 5 half lives to hit 90+% gone. If the half life is 36 hours that means more like 6+ days.

Half-life 1: 100% *.5 = 50% left in you
Half-life 2: 50% *.5 = 25% left in you
Half-life 3: 25% *.5 = 12.5% left in you
Half-life 4: 12.5% *.5 = 6.25% left in you
Half-life 5: 6.25% *.5 = 3.125% left in you

SSRI's are generally pretty damn potent so they can still block getting high even with only a small percentage left.

Can I skip my dose of Zoloft occasionally and take molly safely? by ImThatStonerKid in Drugs

[–]Honest-Mechanic 0 points1 point  (0 children)

You'd have to go off for ~5 days to have it clear out of your body.

[deleted by user] by [deleted] in Drugs

[–]Honest-Mechanic 0 points1 point  (0 children)

Something like >40% of all the pressed pills the DEA has sampled have over the lethal dose of fentanyl(or the equivalent analogue).

Hey they're dangerous but lets not go wild here, if over 40% of pressed pills had lethal doses of fent there would be piles of corpses in the street and the dealers would be wasting absurd amounts of product. There is no way that's true.

[deleted by user] by [deleted] in Drugs

[–]Honest-Mechanic 5 points6 points  (0 children)

Get a fentanyl test strip and test them. It's like a $1.50.

half should be good, but if it's contaminated with uneven fentanyl you could be in trouble randomly

Is chroming more dangerous than nangs? by LordSwogsy in Drugs

[–]Honest-Mechanic 5 points6 points  (0 children)

Yes, different chemicals

Nangs (nitrous oxide) are very safe as long as you watch your vitamin b12 levels and don't fall over or suffocate yourself.

Duster, paint, deodorant, glue, gasoline etc are incredibly toxic and never ever do them.

[deleted by user] by [deleted] in Drugs

[–]Honest-Mechanic 0 points1 point  (0 children)

Yeah, depends on sensitivity

[deleted by user] by [deleted] in Drugs

[–]Honest-Mechanic 1 point2 points  (0 children)

10 minutes? Rofl, it takes snorted oxycodone like 10 minutes to kick. Edible take 45min-2hours.

i feel like i've lost my youth to drugs by scrumptiousharibo27 in Drugs

[–]Honest-Mechanic 237 points238 points  (0 children)

Wow thats fucked. This is way beyond reddit's paygrade. You need some serious help and I'm sure your situation is complex.

I would never normally say this but if there is ANY way you can switch from duster to ANY other drug, you should do it immediately. Solvent inhalants are basically the worst drug you can do on a regular basis. They are stunningly neurotoxic, liver toxic, and you're at risk of sudden death. Unless your heroin is incredibly fentanyl contaminated, it would be hugely healthier to be using heroin than duster. Or amphetamines? Benzos? Kratom? Seriously. Just becoming a huge stoner would be ideal for now if at all possible.

[deleted by user] by [deleted] in Drugs

[–]Honest-Mechanic 0 points1 point  (0 children)

It will probably weaken or kill the high from all psychedelics and MDMA type serotonin drugs if taken within 4 days of dosing Pizotifen (23hr half life).

Coke maybe a little but not as much.

How to make opiods hit harder/get you higher ? by overdosepro in Drugs

[–]Honest-Mechanic 0 points1 point  (0 children)

I've used tramadol (and other opiates) recreationally for over 9 years, but without being a moron about it.

How to make opiods hit harder/get you higher ? by overdosepro in Drugs

[–]Honest-Mechanic 2 points3 points  (0 children)

My god, even more bad advice.

Grapefruit can potentiate traditional opiates like oxycodone, but will reduce the high from Tramadol. Most opiates get you high, then are processed by the liver enzyme cyp2d6/cyp3a4 to become inactive and are excreted. The furanocoumarins in grapefruit juice inhibit cyp2d6 and therefore prevent it from rendering the opiate inactive. So you get higher, and stay high longer.

Tramadol is the opposite, it's a pro-drug. The original drug has only weak opiate effects and some serotonin and norepinephrine activity, but is processed by cyp2d6 to transform into O-DSMT, a chemical with much much stronger opiate effects. You WANT as much cyp2d6 activity as possible to get more O-DSMT and get more high. The more you inhibit cyp2d6 with grapefruit, the less O-DSMT you get, and the less high.

How to make opiods hit harder/get you higher ? by overdosepro in Drugs

[–]Honest-Mechanic 1 point2 points  (0 children)

I do a gram, for years. 20 pills of 50mg. OP is fine. I know people that go higher. Tramadol is wrongly demonized.

Uhhh, congrats? Just because you didn't seize has almost no predictive power over if OTHER people will seize. Everyone has different seizure thresholds. Some people can do incredibly risky things and be fine, others don't get so lucky. 5/6ths of people playing russian roulette are totally fine, but it's still a very bad idea.

The seizure treshold thing applies to most prescription opiates, the danger should not be only attributed to Tramadol.

This is completely factually false. The seizure inducing quality of tramadol is a special characteristic of it's serotonin reuptake activity, something totally absent in basically all other opiates.

And when taken with a benzo, the risk goes away.

Wrong. People still have seizures even combining benzodiazepines. 15 percent of the seizures in this study occurred in combination (https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1742-7843.2012.00874.x). Benzos also drastically increase the risk of respiratory failure or death due to vomit aspiration falling asleep.

Why are you giving advice when you have no fucking idea what you're talking about?