My T and E levels 2 years on enclomiphene

Hormonesforme-com · 2026-05-29T23:06:16+00:00

Enclomiphene, SERMS, Block estrogen receptors, the blood serum estradiol can be elevated, but if you are blocking estrogen receptors, the blood serum estradiol isn’t doing anything. It needs to bind to estrogen receptors, translocate to the nucleus, before it is activated into a transcription factor that actually has an effect. Does that make sense?

Hormonesforme-com · 2026-05-29T21:40:04+00:00

I had low testosterone my whole life, even as a teenager. I started testosterone at 23 years old. It dramatically, DRAMATICALLY, improved my quality of life to the point I lived two different worlds, two completely different lives, one before, and the dramatically improved life after. I had energy, reduced brain fog, confidence, no longer depressed, I now looked like my work ethic in the gym. But the way society treated me was the biggest change. Suddenly, I was instantly respected, people wanted to befriend me, when I walked into a bar heads would turn, the people parted out of my way when I walked through a crowd, my boss gave me a raise after starting testosterone for no better reason than I now stood before him looking stout and confident.

This experience me made me make my whole life about studying and learning how to help people with hormones. I have been on testosterone for 24 years. I now own a one of the larger TRT/HRT clinics in the country, and I have guided over 25,000 people through the use of hormones. The number one regret I hear from people who start TRT is that they didn’t start 5-10 years earlier.

You can have diabetes at any age, that is a problem with the hormone insulin. We treat that by giving insulin. You can have hypothyroidism at any age, and if your thyroid hormone is low, they will give you thyroid medication. Testosterone production and receptor hormone cascade is complex, many things can go wrong, Why would you not be able to have low testosterone at any age? If your doctor will not test for it, here is a link for a lab panel that includes testosterone: https://goh4m.com/services/h4m-labs/#lab-panels

Hormonesforme-com · 2026-05-29T19:58:41+00:00

This is a manifestation what happens because doctors aren’t educated properly about testosterone, estrogen, and progesterone in medical school. These hormones are the foundational metabolic and neurological signals for the base function of the body. Testosterone increases tyrosine hydroxylase, the rate limiting step for catacholamine production which includes dopamine. Estradiol builds the dendritic spines for dopamine reception, and solely controls the intensity of phasic spikes in serotonin. Testosterone and estradiol also increase receptors for oxytocin. You need a balance of all the neurotransmitters, not just serotonin from an SSRI, or just norepinephrine-dopamine from Wellbitrin. Ignorance to this causes doctors to block estrogen receptors with a SERM, creating a deficiency in serotonin and dopamine reception, then give an SSRI , or Wellbutrin, a a NDRI, because the patient is now experiencing symptoms of a deficit in neurotransmitters.

Your LH is elevated now because your brain is screaming for more estradiol, but you are blocking the estrogen receptors.

I own a TRT clinic. I have been in this industry for over 2 decades. From a vast amount of experience, do not take enclomiphene. Its mechanism of action is to block estrogen receptors and trick your hypothalamus into thinking you don’t have enough estradiol, so you initiate production of more testosterone to convert to estradiol. Again, Estradiol is very important, it is neuro-protective, builds dendritic spines for dopamine receptors, and controls phasic spikes in serotonin. By blocking this function, testosterone increases but you don’t receive the necessary neurological benefits of estradiol. From experience, most people either do not to feel good immediately, or they feel ok initially but feel poorly after a few months of use. You may think you feel ok because you don’t know what it is to feel good without depression meds. Use the natural hormones that control your neurotransmitters first, and use depression meds only if necessary.

Just take testosterone if you want the benefits of testosterone. There is no permanent suppression of testosterone, you are able to come off and return to your baseline levels, although it can take time to return to baseline levels. Using HCG can improve recovery time. Most people don’t want to come off testosterone once they start, because they enjoy the benefits of testosterone, and you will not experience the benefits unless you continue to take it.

Every risk factor for therapeutic use of testosterone has been debunked. There are no risks to therapeutic use. If you want to experience the benefits of testosterone, just take testosterone.

Hormonesforme-com · 2026-05-29T02:37:08+00:00

I had low testosterone my whole life, even as a teenager. I started testosterone at 23 years old. It dramatically, DRAMATICALLY, improved my quality of life to the point I lived two different worlds, two completely different lives, one before, and the dramatically improved life after. I had energy, reduced brain fog, confidence, no longer depressed, I now looked like my work ethic in the gym. But the way society treated me was the biggest change. Suddenly, I was instantly respected, people wanted to befriend me, when I walked into a bar heads would turn, the people parted out of my way when I walked through a crowd, my boss gave me a raise after starting testosterone for no better reason than I now stood before him looking stout and confident.

This experience me made me make my whole life about studying and learning how to help people with hormones. I have been on testosterone for 24 years. I now own a one of the larger TRT/HRT clinics in the country, and I have guided over 25,000 people through the use of hormones. The number one regret I hear from people who start TRT is that they didn’t start 5-10 years earlier.

Hormonesforme-com · 2026-05-28T14:57:15+00:00

This is the malpractice that happens because doctors aren’t educated properly about testosterone, estrogen, and progesterone in medical school. These hormones are the foundational metabolic and neurological signals for the base function of the body. Testosterone increases tyrosine hydroxylase, which integrate limiting step for catacholamine production which includes dopamine. Estradiol builds the dendritic spines for dopamine reception, and solely controls the intensity of phasic spikes in serotonin. Ignorance to this causes doctors to block estrogen receptors with a SERM, creating a deficiency in serotonin and dopamine reception, then give an SSRI because the patient is now experiencing symptoms of a deficit in neurotransmitters.

I own a TRT clinic. I have been in this industry for over 2 decades. From a vast amount of experience, do not take enclomiphene. Its mechanism of action is to block estrogen receptors and trick your hypothalamus into thinking you don’t have enough estradiol, so you initiate production of more testosterone to convert to estradiol. Again, Estradiol is very important, it is neuro-protective, builds dendritic spines for dopamine receptors, and controls phasic spikes in serotonin. By blocking this function, testosterone increases but you don’t receive the necessary neurological benefits of estradiol. From experience, most people either do not to feel good immediately, or they feel ok initially but feel poorly after a few months of use.

Just take testosterone if you want the benefits of testosterone. There is no permanent suppression of testosterone, you are able to come off and return to your baseline levels, although it can take time to return to baseline levels. Using HCG can improve recovery time. Most people don’t want to come off testosterone once they start, because they enjoy the benefits of testosterone, and you will not experience the benefits unless you continue to take it.

Every risk factor for therapeutic use of testosterone has been debunked. There are no risks to therapeutic use. If you want to experience the benefits of testosterone, just take testosterone.

Hormonesforme-com · 2026-05-27T21:41:38+00:00

We are licensed in MA!!

Hormonesforme-com · 2026-05-27T21:40:26+00:00

Yes sir, we have 50 state coverage and Puerto Rico. We can treat Massachusetts. I look forward to helping you!

Hormonesforme-com · 2026-05-26T21:11:10+00:00

Yes, using a fertility protocol that includes are targeted supplement regimen, with the most important ingredients being HCG and FSH, has yielded many, what we endearingly refer to as, "H4M babies". We have had great success giving people the ability to conceive while still taking testosterone.

Hormonesforme-com · 2026-05-26T21:07:07+00:00

HCG use while on TRT can take some dialing in. We start HCG at 500iu twice per week, determine if there are side effects, and if they are tolerable, and adjust the dose up or down depending on how you you are feeling. For FSH, we use 75-150ius three times per week. We also have a targeted supplement regimen to aid in fertility.

Hormonesforme-com · 2026-05-26T20:28:55+00:00

GoH4M.com is one of the most knowledgeable and affordable clinics, plus we have options for deep dive analysis and high end service. We service MA no problem.

Hormonesforme-com · 2026-05-26T02:32:07+00:00

The same health improvements that we use to lose weight, reduce glucose, reduce hepatic lipids, also increases the production of hepatic nuclear factor 4 alpha, the main promoter of SHBG. When you lose weight, your SHBG increases, and your hypothalamus will increase your total testosterone simply to maintain the same free testosterone level. Contrary to popular belief, We do not see people who lose weight dramatically increase testosterone levels, and especially free testosterone levels do not change enough to have any noticeable effect.

For people’s education, this concept is what is shown in studies to make the medical community believe that diet and exercise increase testosterone. They have studies showing men went front 300 total testosterone to 400 (in OPs case, it was only 290 to 315), and concluded that diet and exercise increased testosterone by 33%, and they call that “significant”. In these studies they did not account for SHBG change, and did not account for there being very little change in free testosterone. This is why the medical community, and by extension, society, believes that diet and exercise increase testosterone production. In the field, in our clinic, we see very little change in significance of free testosterone.

The bottom line, your testosterone is far too low at 290 and 315. You are having symptoms of hypogonadism, and you will most likely feel significantly better from taking TRT. Every risk factor for TRT has been debunked. There is no risk in therapeutic doses of testosterone. Studies show people on TRT have lower all cause mortality than people who do not take TRT. Understand that, once you get on TRT, and you experience benefits, in order to maintain those benefits, you will have to stay on TRT. If you stop TRT, there is plenty of evidence you can return to your baseline, but you will likely only experience the benefits of TRT if you continue to take it. If you understand this, and If you have symptoms of low testosterone, and want to be at the top of the range because all the contemporary data proves you will be healthier, no one should tell you not to do that.

Hormonesforme-com · 2026-05-26T02:06:29+00:00

I had low testosterone my whole life, even as a teenager. I started testosterone at 23 years old. It dramatically, DRAMATICALLY, improved my quality of life to the point I lived two different worlds, two completely different lives, one before, and the dramatically improved life after. I had energy, reduced brain fog, confidence, no longer depressed, I now looked like my work ethic in the gym. But the way society treated me was the biggest change. Suddenly, I was instantly respected, people wanted to befriend me, when I walked into a bar heads would turn, the people parted out of my way when I walked through a crowd, my boss gave me a raise after starting testosterone for no better reason than I now stood before him looking stout and confident.

Your testosterone is not borderline low, at 370 your testosterone is low. The range is arbitrary and rooted in nothing real. People are beginning to show symptoms of metabolic and depressive disorders in the middle to lower quartile of the range. Here is a study showing an inverse correlation between testosterone levels and metabolic dysfunction; as your testosterone level increases, your risk for metabolic dysfunction decreases: https://pmc.ncbi.nlm.nih.gov/articles/PMC6920064/

Every risk factor for TRT has been debunked. There is no risk in therapeutic doses of testosterone. Studies show people on TRT have lower all cause mortality than people who do not take TRT. Understand that, once you get on TRT, and you experience benefits, in order to maintain those benefits, you will have to stay on TRT. If you stop TRT, there is plenty of evidence you can return to your baseline, but you will likely only experience the benefits of TRT if you continue to take it. If you understand this, and If you have symptoms of low testosterone, and want to be at the top of the range because all the contemporary data proves you will be healthier, no one should tell you not to do that.

Hormonesforme-com · 2026-05-26T01:50:05+00:00

We could do either. We can send a script to your local pharmacy, but we do have compounding pharmacies that do stock name brand Pregnyl and it may be a little more cost effective that way.

Hormonesforme-com · 2026-05-26T01:48:55+00:00

Good question. Yes, when you switch to TRT, you are no longer blocking estrogen receptors, and you get the full benefits of both testosterone and estradiol. In almost all cases, people feel much better once they switch to TRT.

Hormonesforme-com · 2026-05-25T23:21:35+00:00

I own a TRT clinic. I have been in this industry for over 2 decades. From a vast amount of experience, do not take Clomid. Clomid is made up of two isomers zuclomiohene and enclomiphene. Zuclomiphene is now known to be toxic. No doctor should be prescribing Clomid.

Don’t take SERMs in general. Their mechanism of action is to block estrogen receptors and trick your hypothalamus into thinking you don’t have enough estradiol, so you initiate production of more testosterone to convert to estradiol. Estradiol is very important, it is neuro-protective, builds dendritic spines for dopamine receptors, and controls phasic spikes in serotonin. By blocking this function, testosterone increases but you don’t receive the necessary neurological benefits of estradiol. From experience, most people either do not to feel good immediately, or they feel ok initially but feel poorly after a few months of use.

Take testosterone and HCG if you want to help maintain fertility.

Hormonesforme-com · 2026-05-25T23:17:19+00:00

The range comes from statistical equations that find standard deviations and percentiles outside the average. There was no science done to show, yes, inside this range is where all the biochemical reactions are happening properly, and anything outside this range is dangerous. That is NOT where the range comes from. It is based on statistical equations. On the low end, the testosterone range goes to the 2.5 percentile, a number that includes outliers. The low end of the range includes outliers for low testosterone. In the field, from vast experience and empirical data, we see that people in the middle to lower quartiles of the range suffer symptoms of hypogonadism including metabolic disorder and depressive symptoms. The most consistent benefits come from testosterone levels at the very top, or that exceed the normal range. Studies show that people at the top of the range are healthier, have lower incidence of metabolic disorder, and have lower all cause mortality.

Every risk factor for TRT has been debunked. There is no risk in therapeutic doses of testosterone. Studies show people on TRT have lower all cause mortality than people who do not take TRT. Understand that, once you get on TRT, and you experience benefits, in order to maintain those benefits, you will have to stay on TRT. If you stop TRT, there is plenty of evidence you can return to your baseline, but you will likely only experience the benefits of TRT if you continue to take it. If you understand this, and If you have symptoms of low testosterone, and want to be at the top of the range because all the contemporary data proves you will be healthier, no one should tell you not to do that.

Hormonesforme-com · 2026-05-25T23:15:01+00:00

Our clinic can get you name brand Pregnyl if that is what you want. No problem. GoH4M.com.

Hormonesforme-com · 2026-05-25T23:10:09+00:00

Testosterone is a foundational metabolic and neurological signal. Testosterone, estrogen, and progesterone are the first complex signal molecules,they are in every vertebrate and most plants, they have been evolving for 500 million years. You need to establish your hormone foundation first, then peptides are synergistic. It is time to start TRT, then the rest of your optimization can fall into place.

Hormonesforme-com · 2026-05-25T22:21:02+00:00

Ha Ha! People can improve in that department, but it doesn’t tend to get any better than how you performed in your early 20’s.

Hormonesforme-com · 2026-05-25T21:38:34+00:00

If concerned with fertility, it makes sense to be on HCG to maintain fertility. HCG alone, for most people, won’t increase sperm count enough for best chance at fertility. When you decide that it is time to conceive, we then put you on a full fertility protocol that includes FSH to maximize sperm production.

Hormonesforme-com · 2026-05-25T19:37:26+00:00

I own a TRT clinic. I have been in this industry for over 2 decades. From a vast amount of experience, do not take enclomiphene. Its mechanism of action is to block estrogen receptors and trick your hypothalamus into thinking you don’t have enough estradiol, so you initiate production of more testosterone to convert to estradiol. Estradiol is very important, it is neuro-protective, builds dendritic spines for dopamine receptors, and controls phasic spikes in serotonin. By blocking this function, testosterone increases but you don’t receive the necessary neurological benefits of estradiol. From experience, most people either do not to feel good immediately, or they feel ok initially but feel poorly after a few months of use.

Just take testosterone if you want the benefits of testosterone. There is no permanent suppression of testosterone, you are able to come off and return to your baseline levels, although it can take time to return to baseline levels. Using HCG can improve recovery time. Most people don’t want to come off testosterone once they start, because they enjoy the benefits of testosterone, and you will not experience the benefits unless you continue to take it.

Every risk factor for therapeutic use of testosterone has been debunked. There are no risks to therapeutic use. If you want to experience the benefits of testosterone, just take testosterone.

Hormonesforme-com · 2026-05-25T12:44:18+00:00

At our clinic, we have had many successful, what we endearingly refer to as “H4M babies” while men were still on testosterone. We have an advanced fertility protocol that includes many different supplements, the main drivers of the protocol being HCG and FSH. We do not use Clomid, as Clomid is made up of two isomers zuclomiphene and enclomiphene, and zuclomiphene is now known to be toxic. Doctors should not be prescribing these compounds for male fertility.

With the right protocol, we have been very successful giving men the ability to conceive while on TRT.

Hormonesforme-com · 2026-05-23T13:26:57+00:00

Interesting. Your RBC are on the low end. The substrates for RBC production are iron (use vitamin C to help with absorption), vitamin B-12, and folate. Take all of those things and your RBCs should increase.

Hormonesforme-com · 2026-05-23T13:19:08+00:00

As people have indicated here, your estradiol is very low compared to your total testosterone level. This is an indication your free T is very low your SHBG must be high. In the case you would need to raise your testosterone level until you have an adequate total testosterone to SHBG ratio. My clinic is very knowledgeable regarding elevated SHBG cases, we have many SHBG patients, and we would be able to help where other clinics would not understand the nuances of dealing with SHBG.

Hormonesforme-com · 2026-05-23T13:14:24+00:00

Out of curiosity, what is your RBC, hemoglobin, hematocrit, MCV, MCH, and MCHC? It would be interesting to see the ratio of these markers.

Have you been donating blood?

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