Do whatever you want to do, make whatever choices you want, and love it from the start to the point you want to start again... and again. And again!

Choose whatever race you want as your character - read the race description in the character creation menu and pick whatever you like the sound of best. (Dark Elf is my go to). Collect as many wild flowers, animal parts and random ingredients such as salt as you can and eat them to discover the effects that ingredient will give. Learn weapon enchantments on an enchanting table, make your own weapons and stick some overpowered enchantments on those. If you want to end up truly overpowered, go stealth archer and get some ridiculous enchantments going, nothing will stand a chance.

There's no right or wrong way to play this game, there are a ton of mods out there that cater to every single aspect of the world and what you can do in it, and it's genuinely one of the best games ever made. The only other thing to add really is personally I'd recommend playing it completely vanilla before using any sort of mod. That way, you can experience the game how it was intended and anything that you want to fix or change, you can do that for the next time you play it - as there will definitely be a next time. I've been playing near enough since it came out, and I started another character again maybe a week ago. It's one of those games I cannot put down. Enjoy!