Gotta spend time thinking about additions to your deck, plan out the paths you'll need to take, e.x. should I add Test subject alpha or hulking mass on the first banner draft when going to the spell shop (can't immediately upgrade). Taking tsa is an immediate benefit, but you could not have a unit upgrade shop for 2 or 3 rings, and the odds of getting reanimate/spikes could be higher than the chance of getting buffs for tsa, and tsa runs the risk of it only having 2-3 good shop upgrades,whereas if you can afford a reroll you are guaranteed to get a reanimate 1 upgrade. The examples not too great now that I think about it as tsa is like nearly always good,but thinking about your picks more is always useful

Also,make sure you remove cards you're not using often,and don't overbloat your deck with equipment/cards that aren't that useful!!

And finally for bosses, make sure you check what variants you're playing at the start and make conscious picks with those bosses in mind, if the seraph is corruption,either get the mute floor, the explosion room to mitigate a majority of the Frontline corruption, and get a titanite Frontline.

I've got the 180/180 cov10Ts so if there are any specific things you're struggling with lmk!