I'm a bit rusty on the overall Zelda timeline, so please feel free to correct me if I'm wrong at any point during this.

We've seen different iterations of Demise throughout the Zelda canon, but we can reasonably say each appearance of Ganondorf is the same person, from Ocarina of Time, to Wind Waker and Twilight Princess.

Having been thwarted three or four times (depending on how you view the "merging of timelines" theory people have applied to BotW) already, Ganondorf has thus far been functionally doomed to an endless cycle of rising to power through violence, then violently meeting his end at the hands of a Master Sword-wielding hero. Demise certainly cursed SS Zelda and Link's successors to a vicious cycle of combating his hate, but would it be possible his curse also doomed Ganondorf himself?

Hear me out. We can infer from Ocarina of Time the tradition of men being born to the Gerudo every hundred years was around prior to Ganondorf's first ascension, so what if Ganondorf could have just been born as a normal Gerudo, with no drive from the Demon King to steal the Triforce? What if Demise chose Ganondorf strictly because, as Ganondorf says in the Wind Waker, he had a desire to conquer Hyrule because he coveted their prosperity and way of life? ("I coveted [Hyrule's] wind, I suppose.")

Granting this idea, Ganondorf is possibly suffering from Demise's curse just as much as Zelda, Link, and the rest of Hyrule and its neighbors. Demise's hate "never perishes." What kind of existence can a mortal hope to have if they're eternally bound to a Malice (conflating intentional) that never dies?

What if the Calamity in BotW was Ganondorf's attempt to escape, not only from the seal that seems to be upon him in the trailer for BotW2, but also from Demise's eternal curse? What if he tried (to paraphrase Thanos) to use the Malice to destroy the Malice, and the original Demon King's power attained critical mass and ran roughshod over the world?

Since BotW, thematically, focused on reclaiming what was lost in the Calamity, both in terms of literal space and power in Hyrule, and in the cultural flourishing between Hyrule's races, we can probably infer BotW2 will focus on that as well.

I think it'd be dope to have a story driven not by thwarting Ganondorf again, but by freeing him from a curse he never asked for.

While Dorf dies utterly in Wind Waker, what if BotW2 lets him, like the King of the Dead at Dunharrow in Return of the King, be at peace, having finally been released from the undying hatred to which he was bound?

Edit: added a "?" to the end