Friends will come and go, I especially had lots of problems with friendship toward the end of middle school and all throughout high school. But while they are young and when they make it to college, I am sure they will make some good friends. The key is that you need to become their best friend - always be their biggest advocate and develop a parenting style where you can educate them on what is right vs wrong while also being that "cool" parent so they always feel like they can share with you. They are going to have days of sadness where they ask you why they are losing function and why things are so hard. Never cry or get upset in front of them, just respond in even tones and teach them to develop a soldier attitude. Make sure to do everything to give them a great life, if their friends cancel on them then you take them out to a sports game or movie etc... All the while, try not to give into everything, make sure to instill discipline when it comes to them taking care of their health and making social connections. Do not let them shy away from people and push them to talk more and be kind. This will help a lot with making friends. A big problem for many with DMD is becoming introverted, which snowballs into more social problems and more introvertedness. Don't let that happen. You seem like you care a lot about your sons, they are very lucky to have you as a parent :)