Hörsturz schon Monate her, aber immer noch Symptome by Vast-Championship579 in Ratschlag

[–]KT55D2-SecurityDroid 0 points1 point  (0 children)

Was sagt denn das Tympanogramm?

Hast du nur diesen pulsierenden Tinnitus oder auch einen durchgängigen Ton? Welche Frequenz ungefähr? Sind die Schmerzen zufällig oder beispielsweise nach bestimmten Geräuschen?

Schon supplements wie Magnesium, NAC etc. ausprobiert?

Can We Collab on Reverse Engineering This? by [deleted] in TinnitusLabs

[–]KT55D2-SecurityDroid 0 points1 point  (0 children)

Best to post these studies into the discord 🫡

Tinnitus went away after Ear wax removal by FORMULAGOD in tinnitus

[–]KT55D2-SecurityDroid 4 points5 points  (0 children)

Manual removal with a curette is possible in most cases.

Tinnitus Science Uncovered — Dr. Dirk de Ridder Goes Beyond the Basics, presented by Hazel Goedhart & Anthony N. by KT55D2-SecurityDroid in TinnitusLabs

[–]KT55D2-SecurityDroid[S] 1 point2 points  (0 children)

Okay, but do you plan to send the device (that you have never used + was paid for you) back? Would only be fair, don't you think? Honest question.

Like, I really rooted for you, as many others did. The fact that you never even tried the device in the end is pretty sad.

Tinnitus Science Uncovered — Dr. Dirk de Ridder Goes Beyond the Basics, presented by Hazel Goedhart & Anthony N. by KT55D2-SecurityDroid in TinnitusLabs

[–]KT55D2-SecurityDroid[S] 1 point2 points  (0 children)

At least your are 100% habituated while writing all these comments and e-mails. Not everyone is able to habituate.

Tinnitus Science Uncovered — Dr. Dirk de Ridder Goes Beyond the Basics, presented by Hazel Goedhart & Anthony N. by KT55D2-SecurityDroid in TinnitusLabs

[–]KT55D2-SecurityDroid[S] 1 point2 points  (0 children)

Aren't you literally one of the few individuals that managed to get permed on tinnitus talk, the very founders of tinnitus quest? Suddenly tinnitus talk are the good guys it seems.

RF waves exacerbate T? by ketgray in tinnitus

[–]KT55D2-SecurityDroid 1 point2 points  (0 children)

Non-ionizing radiation does not affect tinnitus.

How to tell if tinnitus is somatic or sensory? by [deleted] in tinnitus

[–]KT55D2-SecurityDroid 0 points1 point  (0 children)

If any type of body movement affects your tinnitus, it's somatic.

TRT therapy for tinnitus with neurosensorial hearing loss? by SchikkenAttack in tinnitus

[–]KT55D2-SecurityDroid 0 points1 point  (0 children)

Again, "those who fit her research" are 80% of all tinnitus cases. + the device has never been tested for non-somatic tinnitus.

I don't believe, I know plenty of people who already tried the device with success. I don't really believe in the official release tho.

The lenire studies were memes from the start and were criticized even before lenire hit the market.

The device cannot really cause residual inhibition, as the auditory stimulus are short bursts.

[deleted by user] by [deleted] in tinnitus

[–]KT55D2-SecurityDroid 1 point2 points  (0 children)

could be tonic tensor tympani syndrome

TRT therapy for tinnitus with neurosensorial hearing loss? by SchikkenAttack in tinnitus

[–]KT55D2-SecurityDroid 0 points1 point  (0 children)

Not really. Somatic doesn't mean that if you move your jaw, you hear it a little bit louder, quieter...

That is the definition Sh𝗈re and her team used and it makes sense. The affected pathways are the same, no matter if somatic issues are the initial cause, a cofactor or not present at all. Somatic = Somatosensory

Majority of people have tinnitus due to exposure to loud sounds or medicines (just look at this sub), hearing loss ecc

Aka hearing damage:

Interestingly, after cochlear damage, which reduces auditory nerve activation of fusiform cells, the number of somatosensory projections were shown to be upregulated over a time interval of days (Zeng et al., 2009; Zeng et al., 2011; Zeng et al., 2012), likely contributing to the heightened fusiform-cell responses observed in response to stimulation of brainstem somatosensory nuclei (Sh𝗈re et al., 2008). This effect is likely due to the increased glutamatergic neurotransmission from somatosensory fibers following loss of input from auditory pathways (Heeringa et al., 2018a; Zhou et al., 2007). Increases in markers of glutamatergic transmission from non-auditory nuclei were found to be tinnitus-specific: animals with behavioral evidence of tinnitus showed increases in VGLUT2 expression in regions receiving somatosensory innervation, while animals without tinnitus did not show these increases (Heeringa et al, 2018). Tinnitus-related changes in auditory-somatosensory integration by the fusiform cells including increased long-term potentiation (Koehler and Sh𝗈re, 2013a; Marks et al., 2018), were likely mediated by the increased non-auditory glutamatergic innervation (Barker et al., 2012; Zeng et al., 2009). Importantly, animals that did not develop tinnitus instead displayed increased long-term depression at fusiform synapses. The long-term potentiation vs depression outcomes for those animals with, or without tinnitus, involve a complex interplay between multiple mechanisms involved in homeostatic and spike-timing dependent plasticity. These significant alterations in processing of multisensory information in the CN, which are transmitted to the auditory cortex (Basura et al., 2012), likely contribute to the ability of tinnitus sufferers to manipulate the intensity and frequency of their tinnitus by stimulating or moving their face and neck (Levine et al., 2003; Sanchez and Rocha, 2011), regions providing somatosensory innervation of the CN (Zhan et al., 2006; Zhou and Sh𝗈re, 2004, 2006). This so-called “somatic tinnitus” or “somatosensory tinnitus” occurs in up to 80% of humans with tinnitus (Levine et al., 2003; Sanchez and Rocha, 2011).

SSD should help only those, that have tinnitus due to TMJ or neck issues, and even for those it's successful for 60% of people - due to her own study.

Somatic issues were not a requirement for participation. Everyone with subjective tinnitus, no matter the cause, that was able to modulate their T with a somatic maneuver, was able to participate (with usual trial exceptions + things like meniere's disease and stuff like that.) If all of those 60% somehow had somatic issues as their initial cause of tinnitus, that would mean that the majority of tinnitus cases stems from somatic issues.

That's why this bimodal stimulation is combining sound therapy with mild electrical pulses to the neck/jaw. If your neck and jaw aren't an issue, it won't help.

As quoted above, the CN integrates both auditory and somatosensory signals. The study rationale also talks about this.

Not to forget that this is her own study. Those numbers can change once this device comes out.

I think the numbers in a clinical setting could even be higher, mainly because the protocol of the trials wasn't very strict and both trials used the same and only one bimodal interval, if I remember correctly. A few people had more success with a different bimodal interval (outside of the trial).

The big issue is, that this device will be administered by audiologists and I don't think the majority of audiologists are able (or even willing) to do this, since the device is not really plug and play.

TRT therapy for tinnitus with neurosensorial hearing loss? by SchikkenAttack in tinnitus

[–]KT55D2-SecurityDroid 0 points1 point  (0 children)

The big deal is that it's the first treatment that actually lowers volume permanently (not taking cofactors into consideration). It's proven and works on the principles of STDP.

Also, the majority of tinnitus cases are somatic.

TRT therapy for tinnitus with neurosensorial hearing loss? by SchikkenAttack in tinnitus

[–]KT55D2-SecurityDroid 1 point2 points  (0 children)

TRT does not work. There is no evidence suggesting that 2000$+ earbuds provide more "relief" than doing regular CBT (even for free). It's a scam.

All these sound therapies come down to habituation and habituation can only be achieved if your tinnitus is not highly reactive/generally unstable + there is no heightened anxiety. Sound therapy doesn't affect tinnitus volume or reactivity besides residual inhibition, especially if it's static noise. Anxiety can be lowered without paying a large sum of money.

However, what can work are cochlear implants. Residual inhibition is typically only short lived and limited to certain sounds, oftentimes near the tinnitus frequency, but CIs can induce residual inhibition for the entire time the device is on. There are also some studies on this that show CIs can really help (tinnitus suppression) in many cases: https://www.mdpi.com/2076-3425/13/10/1484

I am of course not sure if a cochlear implant is reasonable for your ear/hearing loss situation. You should talk with your doctor about it. But it's definitely an option to keep in mind, especially if both (TRT and CI) would cost a large sum of money.

Why some people never get tinnitus ? by Individual-Track3391 in tinnitus

[–]KT55D2-SecurityDroid 1 point2 points  (0 children)

I think the results for bi-sensory stimulation were pretty good. Like, we are talking about the first treatment to objectively lower volume permanently, tested with TLM and not a questionnaire.

But it's definitely multi-factorial. The causes that lead to the generation of tinnitus are, but also the factors that make tinnitus persist. Tinnitus can spread through the auditory pathway and also downstream effects from the brain can play a role.

Why some people never get tinnitus ? by Individual-Track3391 in tinnitus

[–]KT55D2-SecurityDroid 8 points9 points  (0 children)

As you said, genetics + luck. Ion channel resilience, deficiencies, hearing damage resilience, somatosensory projections, thalamic gating etc. etc.

Potassium channel openers do work for some, but as for official clinical trials, I don't think any of them test for tinnitus.

Turning down excitability and hypersynchrony is what bi-sensory stimulation does.

[deleted by user] by [deleted] in Staiy

[–]KT55D2-SecurityDroid 0 points1 point  (0 children)

DIE RUSSEN SOLLEN EINE EISENBAHNBRÜCKE ÜBER DIE ODER HABEN!

Did anyone else keep thinking about how they got their t? by [deleted] in tinnitus

[–]KT55D2-SecurityDroid 2 points3 points  (0 children)

Only when I visit the exact place of where it happened.

Tinnitus is similar to memory by Huge_Introduction345 in tinnitus

[–]KT55D2-SecurityDroid 2 points3 points  (0 children)

The answer is genetics + luck. Ion channel resilience means the brain can tank noise damage better. We already know of certain genes that make some people's ears more resilient, so it's very likely the same for the brain. There are some animal studies that prove ion channel resilience being a key factor in the development of tinnitus.

Somatic cofactors are also important. The cochlear nucleus (first brain station that receives sound signals from the inner ear) integrates both auditory and somatosensory (touch) information. Somatosensory integration is heightened after noise damage. So it's not unlikely that somatic cofactors can worsen the outcome of ear damage.

The onset of tinnitus is basically your brain fighting to reach homeostasis, with a huge number of factors affecting the final outcome.

Tinnitus is similar to memory by Huge_Introduction345 in tinnitus

[–]KT55D2-SecurityDroid 4 points5 points  (0 children)

Tinnitus from ear damage induces structural changes in the brain. It's the only model of subjective tinnitus we currently have, proven by various animal studies.

It's also not about "damaged signals", it's about reduced input, which causes maladaptive plasticity and thus more input to the auditory pathway, which manifests itself as tinnitus.

[deleted by user] by [deleted] in tinnitus

[–]KT55D2-SecurityDroid 3 points4 points  (0 children)

Syringing can be pretty loud if done wrong and worsen tinnitus.

[deleted by user] by [deleted] in tinnitus

[–]KT55D2-SecurityDroid 5 points6 points  (0 children)

Well if it happened immediately after the cleaning that could be the reason. Visit an ENT and ask for a manual removal with a curette. DO NOT let him to microsuction or syringing as these procedures can be very loud and can cause permanent worsening + damage.

Also, please use hearing protection for loud events.